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http://hdl.handle.net/10261/117852
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Arenal, Raúl | - |
dc.contributor.author | Matteis, Laura de | - |
dc.contributor.author | Custardoy, Laura | - |
dc.contributor.author | Mayoral, Álvaro | - |
dc.contributor.author | Tence, Marcel | - |
dc.contributor.author | Grazú, Valeria | - |
dc.contributor.author | Fuente, Jesús M. de la | - |
dc.contributor.author | Marquina, Clara | - |
dc.contributor.author | Ibarra, M. Ricardo | - |
dc.date.accessioned | 2015-07-13T07:48:12Z | - |
dc.date.available | 2015-07-13T07:48:12Z | - |
dc.date.issued | 2013 | - |
dc.identifier | doi: 10.1021/nn306028t | - |
dc.identifier | issn: 1936-0851 | - |
dc.identifier | e-issn: 1936-086X | - |
dc.identifier.citation | ACS Nano 7(5): 4006-4013 (2013) | - |
dc.identifier.uri | http://hdl.handle.net/10261/117852 | - |
dc.description.abstract | Spatially resolved electron energy loss spectroscopy (SR-EELS) using scanning transmission electron microscope (STEM) allows the identification and determination of the spatial distribution of the components/elements of immuno-functionalized core-shell superparamagnetic magnetite nanoparticles. Here, we report that SR-EELS measurements allow the direct identification and study of the biological moieties (protein G and anti-HRP antibody) in complex bionanocarriers of relevance for biomedical applications. Our findings show that the biomacromolecules are located on specific areas on the nanoparticles' surface. In addition, efficiency of this functionalization was evaluated by means of biochemical techniques. © 2013 American Chemical Society. | - |
dc.description.sponsorship | J.M.F. thanks the NANOPUZZLE project (ERC-Starting Grant) for financial support. All the authors thank the Fondo Social Europeo for funding. | - |
dc.publisher | American Chemical Society | - |
dc.relation | info:eu-repo/grantAgreement/EC/FP7/239931 | - |
dc.rights | closedAccess | - |
dc.title | Spatially-resolved EELS analysis of antibody distribution on biofunctionalized magnetic nanoparticles | - |
dc.type | artículo | - |
dc.identifier.doi | 10.1021/nn306028t | - |
dc.date.updated | 2015-07-13T07:48:13Z | - |
dc.description.version | Peer Reviewed | - |
dc.language.rfc3066 | eng | - |
dc.contributor.funder | European Commission | - |
dc.contributor.funder | European Research Council | - |
dc.relation.csic | Sí | - |
dc.identifier.funder | http://dx.doi.org/10.13039/501100000780 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100000781 | es_ES |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | No Fulltext | - |
item.cerifentitytype | Publications | - |
item.openairetype | artículo | - |
item.grantfulltext | none | - |
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accesoRestringido.pdf | 15,38 kB | Adobe PDF | Visualizar/Abrir |
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