Fatty acid, phospholipids and health: targeted lipidomic assays in animals, cells and humans

Abstract

Lipids functions in biological systems are defined as structural and energy supply. However recent investigations have stated their involvement in cell signalling, development of certain diseases as well as their treatment. A lipidome comprise a highly diverse array of molecular species what collectively rise to many tens of thousand compounds. AIM: Description of sample preparation and analytical methods used in the lipidomic analysis of plasma, erythrocytes, tissues (brain, liver, adipose tissue…) from human and animals as well as foodstuffs in investigations currently in progress in our laboratory.