Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/114025
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Catalytic enantioselective aza-Henry reactions |
Autor: | Marqués-López, Eugenia CSIC ORCID; Merino, Pedro CSIC ORCID ; Tejero, Tomás CSIC ORCID; Herrera, Raquel P. CSIC ORCID | Palabras clave: | Nucleophilic addition Enantioselectivity Aza-Henry reactions Nitro-Mannich reactions Asymmetric catalysis |
Fecha de publicación: | 2009 | Editor: | Wiley-VCH | Citación: | European Journal of Organic Chemistry 15: 2401-2420 (2009) | Resumen: | Asymmetric aza-Henry reactions provide excellent routes for the synthesis of optically active organic compounds bearing two vicinal different nitrogenated functionalities that can be further transformed into a variety of interesting compounds such as 1, 2-diamines or a-amino acids. The catalytic asymmetric version of the reaction (also called the nitro-Mannich reaction) provides highly efficient access to enantiomerically pure compounds. Both metal-based and organic catalysts can be used to promote these reactions in a enantioselective way; in particular, a great variety of different organocatalysts- including thioureas, N-oxides, quaternary ammonium salts and chiral Brensted acids - have demonstrated their efficiency, as has recently been reported by several research groups. In addition, considerable effort is being made in controlling the syn/anti diastereoselectivities of these reactions when substituted nitroalkanes are used as substrates. In this microreview recent advances, including scope and limitations, are discussed and applications of different catalytic systems for catalytic asymmetric aza-Henry reactions are presented. © Wiley-VCH Verlag GmbH & Co. KGaA. | URI: | http://hdl.handle.net/10261/114025 | DOI: | 10.1002/ejoc.200801097 | Identificadores: | doi: 10.1002/ejoc.200801097 issn: 1434-193X e-issn: 1099-0690 |
Aparece en las colecciones: | (ICMA) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
accesoRestringido.pdf | 15,38 kB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
SCOPUSTM
Citations
197
checked on 20-abr-2024
WEB OF SCIENCETM
Citations
181
checked on 27-feb-2024
Page view(s)
321
checked on 23-abr-2024
Download(s)
105
checked on 23-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.