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Title

Organocatalysis in enantioselective α-functionalization of 2-cyanoacetates

AuthorsDíaz de Villegas, María D. ; Gálvez, José A. ; Badorrey, Ramón ; López-Ram-de-Víu, Pilar
KeywordsCyano esters
Enantioselectivity
Organic catalysis
Synthetic methods
Cyanides
Issue Date2014
PublisherWiley-VCH
CitationAdvanced Synthesis and Catalysis 356(16): 3261-3288 (2014)
AbstractRecent progress in asymmetric organocatalysis has led to the development of several asymmetric transformations that employ various substrates. Among these, cyanoacetates have emerged as excellent nucleophiles in conjugate addition, alkylation, Mannich and a-heterofunctionalization reactions. In this review we discuss the enantioselective functionalization of 2-cyanoacetates through organocatalytic reactions.
URIhttp://hdl.handle.net/10261/111668
DOI10.1002/adsc.201400404
Identifiersdoi: 10.1002/adsc.201400404
issn: 1615-4150
e-issn: 1615-4169
Appears in Collections:(ISQCH) Artículos
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