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The bio-oscillator: A circuit for cell-culture assays

AuthorsHuertas, Gloria ; Maldonado, Andrés ; Yúfera, A. ; Rueda, Adoración ; Huertas-Díaz, J. L.
Issue Date2015
PublisherInstitute of Electrical and Electronics Engineers
CitationIEEE Transactions on Circuits and Systems - II - Express Briefs, 62(2): 164-168 (2015)
AbstractA system for cell-culture real-time monitoring using an oscillation-based approach is proposed. The system transforms a cell culture under test into a suitable “biological” oscillator, without needing complex circuitry for excitation and measurement. The obtained oscillation parameters are directly related to biological test, owed to an empirically extracted cell–electrode electrical model. A discrete prototype is proposed and experimental results with living cell culture are presented, achieving the expected performances.
Publisher version (URL)http://dx.doi.org/10.1109/TCSII.2014.2386233
Appears in Collections:(IMSE-CNM) Artículos
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