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Título: | Hepatic marker enzymes, biochemical parameters and pathological effects in lambs experimentally infected with Dicrocoelium dendriticum (Digenea) |
Autor: | Manga-González, M. Yolanda CSIC ; Ferreras, Mª del Carmen CSIC ORCID ; Campo, Raquel; González Lanza, Camino CSIC ORCID ; Pérez Pérez, Valentín CSIC ORCID ; García Marín, Juan Francisco CSIC | Palabras clave: | León Province Mast-cells NW Spain Sheep Liver Dicroceliosis Histopathology Fascioliasis Elimination Prevalence |
Fecha de publicación: | 2004 | Editor: | Springer Nature | Citación: | Parasitology Research 93(5): 344-355 (2004) | Resumen: | Hepatic enzymes and biochemical parameter values were analysed in the sera of 32 lambs: 12 infected with 1,000 Dicrocoelium dendriticum metacercariae, 12 with 3,000 and eight controls. Blood samples were collected at intervals of 30 days from day 0 post-infection (p.i.). Half the lambs in each group were slaughtered on days 60 and 180 p.i, respectively. A histopathological and ultrastructural study was carried out on the liver, gall bladder and hepatic lymph nodes of all animals. A minute increase was detected in the bilirubin (7%) and albumin (3%) values in the infected lambs (with 30–2,063 worms) in comparison with those of the controls. The hepatic enzyme values did increase, above all aspartate aminotransferase (19%) and alanine aminotransferase (22%), mainly in the lambs tested with 3,000 metacercariae (38% and 48%, respectively). The increase was significant 60 days p.i. The severity of the lesions was closely associated with the parasite burden. | Descripción: | 12 pages, 5 figures.-- PMID: 15197580 [PubMed].-- Available online 10 Jun 2004. | Versión del editor: | http://dx.doi.org/10.1007/s00436-004-1128-2 | URI: | http://hdl.handle.net/10261/10480 | DOI: | 10.1007/s00436-004-1128-2 | ISSN: | 0932-0113 |
Aparece en las colecciones: | (IGM) Artículos |
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