Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/100000
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Combining chip-ESI with APLI (cESILI) as a multimode source for analysis of complex mixtures with ultrahigh-resolution mass spectrometry |
Autor: | Schmitt-Kopplin, Philippe; Englmann, Matthias; Rosselló-Mora, Ramón CSIC ORCID; Schiewek, Ralf; Brockmann, Klaus Josef; Benter, Thorsten; Schmitz, Oliver Johannes | Palabras clave: | Oil Mass spectrometry FT-ICR MS ESILI APLI |
Fecha de publicación: | 2008 | Editor: | Springer Nature | Citación: | Analytical and Bioanalytical Chemistry 391(8): 2803-2809 (2008) | Resumen: | Recently we have established atmospheric-pressure laser ionisation (APLI) as a method for coupling time-of-flight mass spectrometric detectors (TOF MS) with chromatographic systems (HPLC and GC) to allow two-photon ionisation of non-polar aromatic compounds. Here we demonstrate that APLI can be combined with chip-electrospray ionisation (cESI) coupled to Fourier-transform-ion cyclotron resonance mass spectrometry (FT-ICR MS) for ultrahigh-resolution analysis of complex samples. With the laser turned off, the analytes are ionised only by ESI, whereas when the laser is switched on non-polar aromatic substances also are ionised. In combination with the extremely high mass resolution of an FT-ICR MS, simultaneous qualitative analysis of polar and non-polar analytes is possible in both positive and negative modes, as is exemplified with a crude oil sample. Nevertheless, ion suppression was observed (up to ca. 70% for D 10-pyrene) and thus sample preparation with chromatographic or electrophoretic pre-separation is necessary for quantitative analysis of targets. In addition, for the first time, the dopant-assisted APLI method in combination with cESI (DA-cESILI) was used for determination of 1-nitrocoronene. © 2008 Springer-Verlag. | Versión del editor: | http://dx.doi.org/10.1007/s00216-008-2211-9 | URI: | http://hdl.handle.net/10261/100000 | DOI: | 10.1007/s00216-008-2211-9 | Identificadores: | doi: 10.1007/s00216-008-2211-9 issn: 1618-2642 |
Aparece en las colecciones: | (IMEDEA) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
accesoRestringido.pdf | 15,38 kB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
SCOPUSTM
Citations
42
checked on 13-abr-2024
WEB OF SCIENCETM
Citations
40
checked on 25-feb-2024
Page view(s)
534
checked on 19-abr-2024
Download(s)
118
checked on 19-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.