2024-03-28T12:45:59Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/1223312020-01-15T08:32:40Zcom_10261_66com_10261_3col_10261_319
Cell adhesion on ti surface with controlled roughness
Burgos-Asperilla, Laura
García-Alonso, M. C.
Escudero Rincón, María Lorenza
Alonso, C.
Comunidad de Madrid
Ministerio de Ciencia e Innovación (España)
Ministerio de Educación y Ciencia (España)
© 2015 CSIC. In this report, the in situ interaction between Saos-2 osteoblast cells and a smooth Ti surface was examined over time. The adhesion kinetics and mechanisms of cellular proliferation were monitored by quartz crystal microbalance (QCM) and electrochemical impedance spectroscopy (EIS). The rate of Saos-2 attachment on Ti surfaces, obtained from the measurements performed with the QCM, is a first-order reaction, with k=2.103 min1. The impedance measurements indicate that in the absence of cells, the Ti resistance diminishes over time (7 days), due to the presence of amino acids and proteins from the culture medium that have been a dsorbed, while in the presence of osteoblasts, this decrease is much greater because of the compounds generated by the cells that accelerate the dissolution of Ti.
2015
2015-09-18T12:42:28Z
artículo
Revista de Metalurgia 51(2): e044 (2015)
http://hdl.handle.net/10261/122331
10.3989/revmetalm.044
http://dx.doi.org/10.13039/501100004837
http://dx.doi.org/10.13039/100012818
eng
Publisher's version
http://dx.doi.org/10.3989/revmetalm.044
Sí
S2009/PPQ-1642/AVANSENS
openAccess
Consejo Superior de Investigaciones Científicas (España)