2024-03-29T04:43:41Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/673432017-06-02T10:53:42Zcom_10261_54com_10261_1col_10261_307
C-PON immunoreactive neurons in the neostriatum of the hedgehog (Erinaceus europaeus): A correlated light- and electron-microscopic study
Villalba, Rosa M.
Martínez-Murillo, Ricardo
Polak, J. M.
Rodrigo García, José
The present study provides light- and electron-microscopic immunocytochemical data on the presence of neurons that are immunoreactive to the C-terminal flanking peptide of neuropeptide Y, C-PON, in the neostriatum of the hedgehog (Erinaceus europaeus). Positive neurons have mostly fusiform or round perikarya from which two to four poorly branched processes arise. Immunostained fibers and puncta are also evenly distributed throughout the neostriatum. Ultrastructurally, each neuron exhibits a deeply invaginated nucleus surrounded by abundant cytoplasm with a well-developed rough endoplasmic reticulum and Golgi apparatus. Positive neurons receive symmetric and asymmetric synapses from unlabeled terminals. The results of this study can be correlated with previous findings, as the C-PON-positive neurons of the hedgehog resemble medium-sized neostriatal neurons that are known to be local circuit neurons exhibiting C-PON in the rat. Thus, a high degree of C-PON neuronal system phylogenetic conservation and function can be postulated for the neostriatum of mammals.
Peer Reviewed
2013-02-26T08:50:06Z
2013-02-26T08:50:06Z
1994
2013-02-26T08:50:06Z
artículo
http://purl.org/coar/resource_type/c_6501
doi: 10.1007/s004410050145
issn: 0302-766X
Cell and Tissue Research 277: 177-181 (1994)
http://hdl.handle.net/10261/67343
10.1007/s004410050145
en
none
Springer