2024-03-28T21:38:14Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/727442020-11-18T14:45:41Zcom_10261_86com_10261_1col_10261_339
De la Rosa, Enrique J.
Pablo, Flora de
2000
Trends in Neurosciences 23(10):454-458(2000)
0166-2236
http://hdl.handle.net/10261/72744
10.1016/S0166-2236(00)01628-3
1878-108X
The important effect of cell death on projecting neurons during development is well established. However, this mainstream research might have diverted recognition of the cell death that occurs at earlier stages of neural development, affecting proliferating neural precursor cells and young neuroblasts. In this article, we briefly present observations supporting the occurrence of programmed cell death during early neural development in a regulated fashion that to some extent parallels the death of projecting neurons lacking neurotrophic support. These findings raise new questions, in particular the magnitude and the role of this early neural cell death. Copyright (C) 2000 Elsevier Science Ltd.
eng
closedAccess
Cell death in early neural development: Beyond the neurotrophic theory
artÃculo