2024-03-29T04:35:37Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/250412015-11-05T13:48:00Zcom_10261_22com_10261_1col_10261_275
Rodrigues, Tiago B.
Fonseca, Carla P.
Castro, M. Margarida C. A.
Cerdán, Sebastián
Geraldes, Carlos F. G. C.
2010-06-07T09:33:32Z
2010-06-07T09:33:32Z
2009-12
Quarterly journal of nuclear medicine and molecular imaging 53(6): 631-645 (2009)
1824-4785
http://hdl.handle.net/10261/25041
http://dx.doi.org/10.13039/501100001871
http://dx.doi.org/10.13039/501100000780
http://dx.doi.org/10.13039/501100003381
http://dx.doi.org/10.13039/100012818
An overview of 13C nuclear magnetic resonance (NMR) spectroscopy methods and their applications in the study of the metabolism of brain cells in vitro and in the in vivo brain is presented as well as their implications for modern molecular imaging techniques. Various topics will be discussed, such as general properties of the 13C NMR spectrum, 13C NMR spectroscopy acquisition protocols, determination of fractional 13C enrichment, 13C(2H) NMR methodologies, and the use of 13C hyperpolarized substrates for NMR spectroscopy and imaging. Some illustrative applications are described, both in vitro and in vivo.
eng
openAccess
Magnetic resonance spectroscopy
Brain
Cells brain
Metabolism
13C NMR tracers in neurochemistry: implications for molecular imaging
artículo