2024-03-28T18:40:31Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/1690262021-12-28T16:00:34Zcom_10261_90com_10261_4col_10261_343
DIGITAL.CSIC
author
Pérez, Pablo
author
Huertas, Gloria
author
Olmo, Alberto
author
Maldonado, Andrés
author
Serrano, Juan A.
author
Martín, María E.
author
Daza, Paula
author
Yúfera, A.
funder
Ministerio de Economía y Competitividad (España)
funder
European Commission
funder
Universidad de Sevilla
2018-08-22T08:33:22Z
2018-08-22T08:33:22Z
2018-08-03
Sensors 18(8): 2550 (2018)
1424-8220
http://hdl.handle.net/10261/169026
10.3390/s18082550
http://dx.doi.org/10.13039/100009042http://dx.doi.org/10.13039/501100000780http://dx.doi.org/10.13039/501100003329
30081533
A smart sensor system for cell culture real-time supervision is proposed, allowing for a significant reduction in human effort applied to this type of assay. The approach converts the cell culture under test into a suitable “biological” oscillator. The system enables the remote acquisition and management of the “biological” oscillation signals through a secure web interface. The indirectly observed biological properties are cell growth and cell number, which are straightforwardly related to the measured bio-oscillation signal parameters, i.e., frequency and amplitude. The sensor extracts the information without complex circuitry for acquisition and measurement, taking advantage of the microcontroller features. A discrete prototype for sensing and remote monitoring is presented along with the experimental results obtained from the performed measurements, achieving the expected performance and outcomes.
openAccess
Smart sensing
Bioimpedance
Cell culture
OBT
Real-time monitoring
Remote Cell Growth Sensing Using Self-Sustained Bio-Oscillations
artículo
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URL
https://digital.csic.es/bitstream/10261/169026/1/sensors-18-02550.pdf
File
MD5
cc767e3f371b6aee7147074409328ce6
3781328
application/pdf
sensors-18-02550.pdf