2024-03-28T11:11:45Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/2118102020-12-11T08:53:30Zcom_10261_48com_10261_5col_10261_301
00925njm 22002777a 4500
dc
González, Antonio G.
author
Brouard, Ignacio
author
León, Francisco
author
Padrón, Juan I.
author
Bermejo, Jaime
author
2001-04-30
The acetyl group was chemoselectively cleaved in the presence of p-toluenesulfonic acid (p-TsOH) in CH2Cl2/MeOH without affecting the benzoyl (benzoate and p-bromobenzoate) groups and no transesterification product was observed. The treatment of protected carbohydrates with p-TsOH·H2O at room temperature usually required a longer reaction time than at 40°C. Other types of sulfonic acid such as 10-camphorsulfonic (CSA) led to similar results.
Tetrahedron Letters 42(18): 3187-3188 (2001)
http://hdl.handle.net/10261/211810
10.1016/S0040-4039(01)00406-3
http://dx.doi.org/10.13039/501100000780
Hemoselective deacetylation
Benzoyl
p-bromobenzoyl
p-toluenesulfonic acid
A facile chemoselective deacetylation in the presence of benzoyl and p-bromobenzoyl groups using p-toluenesulfonic acid