2024-03-28T16:42:41Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/295372020-05-14T09:50:28Zcom_10261_33com_10261_5col_10261_286
2010-11-25T13:56:53Z
urn:hdl:10261/29537
Exploiting [2+2] cycloaddition chemistry: achievements with allenes
Alcaide, Benito
Almendros, Pedro
Arangocillo, Cristina
34 páginas, 8 figuras, 100 esquemas.-- Critical review.
The allene moiety represents an excellent partner for the [2+2] cycloaddition with alkenes and alkynes, affording the cyclobutane and cyclobutene skeletons in a single step. This strategy has been widely studied under thermal, photochemical and microwave induced conditions. More recently, the use of transition metal catalysis has been introduced as an alternative relying on the activation of the allenic component. On the other hand, the intramolecular version has attracted much attention as a strategy for the synthesis of polycyclic compounds in a regio- and stereoselective fashion. This critical review focuses on the most recently developed [2+2] cycloadditions on allenes along with remarkable early works accounting for the mechanism, the regio- and diastereoselectivity of the cycloadducts formed (103 references).
2010-11-25T13:56:53Z
2010-11-25T13:56:53Z
2010
artículo
Chemical Society Reviews 39(2): 783-816 (2010)
0306-0012
http://hdl.handle.net/10261/29537
10.1039/B913749A
eng
http://dx.doi.org/10.1039/B913749A
openAccess
Royal Society of Chemistry (UK)