2024-03-29T06:16:54Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/1790052019-04-02T01:15:19Zcom_10261_56com_10261_3com_10261_25com_10261_1col_10261_309col_10261_278
2019-04-01T09:38:52Z
urn:hdl:10261/179005
Honeycomb patterned surfaces functionalized with polypeptide sequences for recognition and selective bacterial adhesion
Sanz, Alberto
Rodríguez Hernández, Juan
Cortajarena, Aitziber L.
European Commission
Ministerio de Ciencia e Innovación (España)
Fundación Instituto Madrileño de Estudios Avanzados en Nanociencia
Bacterial adhesion
Molecular recognition
Biomolecular patterning
Honeycomb structures
Polymer surfaces
Breath figures
We report on the preparation of functional polymer surfaces with controlled topography by using the breath figures approach. The resulting surfaces prepared from a mixture of a PS-b-PAA diblock copolymer and a homopolymer (PS) exhibit pores that are mainly composed of diblock copolymer whereas the rest of the surface is formed by homopolymer. The formation of a hexagonal assembly of pores was achieved by controlling several parameters during the casting process including relative humidity, composition of the blend and polymer concentration. A selective modification of the pore inner part by using appropriate polypeptide sequences permitted the use of these surfaces as scaffolds for pattern and display of active biomolecules, as ordered templates for specific recognition processes and finally for the micropatterning of bacterial cells.
2019-04-01T09:38:52Z
2019-04-01T09:38:52Z
2013-02
2019-04-01T09:38:52Z
artículo
Biomaterials 34(5): 1453-1460 (2013)
0142-9612
http://hdl.handle.net/10261/179005
10.1016/j.biomaterials.2012.10.074
http://dx.doi.org/10.13039/501100000780
http://dx.doi.org/10.13039/501100004837
eng
https://doi.org/10.1016/j.biomaterials.2012.10.074
Sí
info:eu-repo/grantAgreement/EC/FP7/246688
closedAccess
Elsevier