2024-03-28T22:38:06Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/1712502020-12-10T07:39:31Zcom_10261_70com_10261_2col_10261_323
2018-10-19T07:04:43Z
urn:hdl:10261/171250
Comparison of definitions for the metabolic syndrome in adolescents. The HELENA study
Vanlancker, Tine
Schaubroeck, Emmily
Vyncke, K. E.
Cadenas-Sanchez, Cristina
Breidenassel, C.
González Gross, Marcela
Gottrand, Frederic
Moreno, Luis A.
Béghin, Laurent
Molnár, Dénes
Manios, Yannis
Gunter, Marc J.
Widhalm, Kurt
Leclercq, Catherine
Dallongeville, J.
Marcos, Ascensión
Kafatos, Anthony
Castillo, Manuel J.
De Henauw, Stefaan
Ortega, F. B.
Huybrechts, Inge
Ministerio de Economía y Competitividad (España)
Ministerio de Ciencia e Innovación (España)
European Commission
Research Foundation - Flanders
Insulin resistance
Metabolic risk factors
Metabolic criteria
Youth
On behalf of the HELENA project group.
Various definitions are used to define metabolic syndrome in adolescents. This study aimed to compare, in terms of prevalence and differences, five frequently used definitions for this population: International Diabetes Federation, National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP) modified by Cook, pediatric American Heart Association (AHA), World Health Organization, and Jolliffe and Janssen. A sample of 1004 adolescents (12.5–17.0 years) from the Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) study was considered. The components of the definitions (waist circumference/BMI, plasma lipids, glycemia, and blood pressure) were applied, and definitions were compared by using crosstabs, sensitivity, specificity, and kappa coefficient. The prevalence of metabolic syndrome varied from 1.6 to 3.8% depending on the used definitions. Crosstabs comparing the definitions showed the fewest cases being misclassified (having metabolic syndrome or not) between NCEP-ATP and AHA. Analyses for kappa coefficient, sensitivity, and specificity confirmed this finding. [Conclusion]: The different definitions do not classify the same adolescents as having MS and prevalence varied between diagnostic methods. The modified NCEP-ATP and the AHA definitions were most analogous in defining subjects as having metabolic syndrome or not.
2018-10-19T07:04:43Z
2018-10-19T07:04:43Z
2017
2018-10-19T07:04:44Z
artículo
European Journal of Pediatrics 176(2): 241-252 (2017)
http://hdl.handle.net/10261/171250
10.1007/s00431-016-2831-6
http://dx.doi.org/10.13039/501100000780
http://dx.doi.org/10.13039/501100004837
http://dx.doi.org/10.13039/501100003329
http://dx.doi.org/10.13039/501100003130
28058532
eng
Sí
closedAccess
Springer Nature