2024-03-28T20:59:41Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/1314022019-04-05T07:50:24Zcom_10261_109com_10261_1col_10261_362
2016-04-25T11:11:09Z
urn:hdl:10261/131402
Assessing the role of TUBA4A gene in frontotemporal degeneration
Dols-Icardo, Oriol
Valdivia, Jessica
Cardona, Fernando
Pérez-Tur, Jordi
Clarimón, Jordi
Centro Investigación Biomédica en Red Enfermedades Neurodegenerativas (España)
Ministerio de Economía y Competitividad (España)
Nafarroako Gobernua
Instituto de Salud Carlos III
Fundació La Marató de TV3
Dols-Icardo, O. et al. Assessing the role of TUBA4A gene in frontotemporal degeneration. Neurobiology of Aging 38:215.e13-4 (2016). Artículo: 2 páginas y 1 tabla como material suplementario
The tubulin alpha 4a (TUBA4A) gene has been recently associated with amyotrophic lateral sclerosis. Interestingly, some of the mutation carriers were also diagnosed with frontotemporal degeneration (FTD) or mild cognitive impairment. With the aim to investigate the role of TUBA4A in FTD, we screened TUBA4A in a series of 814 FTD patients from Spain. Our data did not disclose any nonsense or missense variant in the cohort, thus suggesting that TUBA4A mutations are not associated with FTD.
The tubulin alpha 4a (TUBA4A) gene has been recently associated with amyotrophic lateral sclerosis. Interestingly, some of the mutation carriers were also diagnosed with frontotemporal degeneration (FTD) or mild cognitive impairment. With the aim to investigate the role of TUBA4A in FTD, we screened TUBA4A in a series of 814 FTD patients from Spain. Our data did not disclose any nonsense or missense variant in the cohort, thus suggesting that TUBA4A mutations are not associated with FTD.
2016-04-25T11:11:09Z
2016-04-25T11:11:09Z
2015-11-05
artículo
Neurobiology of Aging 38:215.e13-4 (2016)
0197-4580
http://hdl.handle.net/10261/131402
10.1016/j.neurobiolaging.2015.10.030
1558-1497
http://dx.doi.org/10.13039/501100003329
http://dx.doi.org/10.13039/501100004587
http://dx.doi.org/10.13039/100008666
eng
Postprint
http://dx.doi.org/10.1016/j.neurobiolaging.2015.10.030
Sí
http://creativecommons.org/licenses/by-nc-nd/4.0/
openAccess
Elsevier