2024-03-29T09:18:08Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/1178092020-12-09T18:00:01Zcom_10261_33com_10261_5com_10261_31891com_10261_2col_10261_286col_10261_31892
2015-07-10T09:18:10Z
urn:hdl:10261/117809
Use of room temperature ionic liquids for the selective fractionation of bioactive ketoses from aldoses
Carrero-Carralero, Cipriano
Ruiz Aceituno, Laura
Ramos, Lourdes
Sanz, M. Luz
Moreno, F. Javier
Ministerio de Ciencia e Innovación (España)
Ministerio de Economía y Competitividad (España)
European Commission
Consejo Superior de Investigaciones Científicas (España)
Fractionation
Aldoses
Ketoses
Room temperature ionic liquids
Activated charcoal
This work deals with the effective fractionation of bioactive ketoses, i.e. lactulose and tagatose, from their corresponding aldoses, lactose and galactose, in equimolar binary mixtures driven by room temperature ionic liquids, i.e. 1-ethyl-3-methylimidazolium dicyanamide ([EMIM][DCA]) and 1-butyl-3-methylimidazolium methyl sulfate ([BMIM][MeSO<inf>4</inf>]), respectively. Under assayed conditions, tagatose was found to be 6-fold more soluble on [BMIM][MeSO<inf>4</inf>] than galactose; meanwhile lactulose was 3 times more soluble than lactose on [EMIM][DCA]. As an application example in a more complex sample, a lactose isomerization mixture containing in addition lactulose and monosaccharides was enriched in this ketose by using [EMIM][DCA]. Carbohydrates were then successfully recovered from the ionic liquid following an activated charcoal-based treatment. Overall, lactulose content was enriched from a 24% in the initial isomerization reaction mixture to a 62% in the purified sample. These experimental results demonstrated the potential of ionic liquids as green alternative solvents for the selective fractionation of bioactive ketoses from their corresponding aldoses in food and beverage production.
2015-07-10T09:18:10Z
2015-07-10T09:18:10Z
2015
2015-07-10T09:18:10Z
artículo
Separation and Purification Technology 149: 140-145 (2015)
http://hdl.handle.net/10261/117809
10.1016/j.seppur.2015.05.016
http://dx.doi.org/10.13039/501100004837
http://dx.doi.org/10.13039/501100003329
http://dx.doi.org/10.13039/501100000780
http://dx.doi.org/10.13039/501100003339
eng
Postprint
https://doi.org/10.1016/j.seppur.2015.05.016
http://creativecommons.org/licenses/by-nc-nd/4.0/
openAccess
Elsevier