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Browsing by Author Varela, Ignacio

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RightsPreviewIssue DateTitleAuthor(s)Type
openAccessfunctionalTLR10.pdf.jpg2016A functional variant of TLR10 modifies the activity of NFkB and may help predict a worse prognosis in patients with rheumatoid arthritisTorices, Silvia; Varela, Ignacio ; Fernández-Luna, J. L.artículo
openAccessBrafV600E.pdf.jpg2013A genetic progression model of BrafV600E-induced intestinal tumorigenesis reveals targets for therapeutic interventionRad, Roland; Varela, Ignacio ; Calvanese, Vincenzo; Bradley, Allanartículo
openAccesspancreaticancer.pdf.jpg2014A next-generation dual-recombinase system for time and host specific targeting of pancreatic cancerSchönhuber, Nina; Varela, Ignacio ; Saur, Dieterartículo
closedAccessaccesoRestringido.pdf.jpg2014A novel mutation in ADAMTS13 of a child with Upshaw-Schulman SyndromePérez-Rodríguez, A.; Batlle-López, Ana; Blanco, Rosa ; Varela, Ignacio ; León, Javier ; Delgado, M. Dolores ; López-Fernández, M. F.artículo
closedAccessaccesoRestringido.pdf.jpg2016Activated KRAS cooperates with MLLAF4 to promote extramedullary engraftment and migration of cord blood CD34+ HSPC but is insufficient to initiate leukemiaPrieto, Cristina ; Agraz-Doblas, Antonio; Varela, Ignacio ; Menendez, Pabloartículo
openAccessclaritychallenge.pdf.jpg2014An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY ChallengeBrownstein, Catherine A.; Beggs, Alan H.; Barrera, Jorge ; García-Lobo, Juan M. ; González-Lamuño, Domingo; Llorca, Javier; Rodríguez, María Cruz ; Varela, Ignacio ; Kohane, Isaac S.; Margulies, David M.artículo
openAccessanalytarge.pdf.jpg2017Analysis of the mutational landscape of classic Hodgkin lymphoma identifies disease heterogeneity and potential therapeutic targetsMata, Elena; Sánchez-Beato, Margarita; Varela, Ignacio ; Piris, Miguel A.; García, Juan F.artículo
openAccessAdenocarcinoma Specimens.PDF.jpg2015Colorectal adenomas contain multiple somatic mutations that do not coincide with synchronous adenocarcinoma specimensVaqué, José P.; Varela, Ignacio ; Moreno, Thaidy; Piris, Miguel A.artículo
openAccesstargeted DNA capture.pdf.jpg2013Detailed molecular characterisation of acute myeloid leukaemia with a normal karyotype using targeted DNA captureVarela, Ignacio ; Moreno, Teresa ; Rad, Roland; Vassiliou, George S.artículo
closedAccessaccesoRestringido.pdf.jpg2016Development and validation of a comprehensive genomic diagnostic tool for myeloid malignanciesMcKerrell, Thomas; Moreno, Thaidy; Varela, Ignacio ; Vassiliou, George S.artículo
closedAccessaccesoRestringido.pdf.jpg2016Development of new cell genetic tracing tools for the study of intratumour heterogeneityQuevedo, Laura; González-Silva, Laura; Moreno, Thaidy; Revilla, Carlos ; Saur, Dieter; Rad, Roland; Varela, Ignacio póster de congreso
openAccesssynchronous VHL.pdf.jpg2014Development of synchronous VHL syndrome tumors reveals contingencies and constraints to tumor evolution.Fisher, Rosalie; Gerlinger, Marco; Varela, Ignacio ; Swanton, Charlesartículo
openAccessdevelopluri.pdf.jpg2016Development refractoriness of MLL-rearranged human B cell acute leukemias to reprogramming into pluripotencyMuñoz-López, Alvaro; Prieto, Cristina ; Agraz-Doblas, Antonio; Varela, Ignacio ; Menendez, Pabloartículo
closedAccessaccesoRestringido.pdf.jpg2017Evaluation of Toll-like-receptor gene family variants as prognostic biomarkers in rheumatoid arthritisTorices, Silvia; Alvarez-Rodríguez, Lorena; Varela, Ignacio ; Muñoz, Pedro; Balsa, Alejandro; López-Hoyos, M.; Martinez-Taboada, Víctor; Fernández-Luna, J. L.artículo
closedAccessaccesoRestringido.pdf.jpg2018Evolutionary routes and KRAS dosage define pancreatic cancer phenotypesMueller, Sebastian; Engleitner, Thomas; Maresch, Roman; Zukowska, Magdalena; Lange, Sebastian; Kaltenbacher, Thorsten; Konukiewitz, Björn; Öllinger, Rupert; Zwiebel, Maximilian; Strong, Alex; Yen, Hsi-Yu.; Banerjee, Pradeep; Louzada, S.; Fu, Beiyuan; Seidler, Barbara; Götzfried, Juliana; Schuck, Kathleen; Hassan, Zonera; Arbeiter, Amdreas; Schönhuber, Nina; Klein, Sabine; Veltkamp, Christian; Friedrich, Mathias; Rad, Lena; Barenboim, Maxim; Ziegenhain, Christoph; Hess, Julia; Dovey, Oliver M.; Eser, Stefan; Parekh, Swati; Constantino-Casas, Fernando; Rosa, Jorge de la; Sierra, Marta I.; Fraga, Mario F.; Mayerle, Julia; Klöppel, Günter; Cadiñanos, Juan; Liu, Pentao; Vassiliou, George S.; Weichert, Wilko; Steiger, Katja; Enard, Wolfgang; Schmid, Roland M.; Yang, Fengtang; Unger, Kristian; Schneider, Günter; Varela, Ignacio ; Bradley, Allan; Saur, Dieter; Rad, Rolandartículo
openAccess2011Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinomaVarela, Ignacio artículo
closedAccessaccesoRestringido.pdf.jpg2017Genomic and transcriptomic landscape of t(4;11)(q21q24)/MLL-AF4+ Infant pro-B acute lymphoblastic leukemiaAgraz-Doblas, Antonio; Varela, Ignacio ; Menendez, Pablopóster de congreso
openAccessmultiregion sequencing.pdf.jpg2014Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencingGerlinger, Marco; Varela, Ignacio ; Swanton, Charlesartículo
openAccessidentimiceletter.pdf.jpg2016Identification of a germline F692L drug resistance variant in cis with Flt3-internal tandem duplication in knock-in miceDovey, Oliver M.; Varela, Ignacio ; Vassiliou, George S.artículo
closedAccessaccesoRestringido.pdf.jpg2011Identification of recurrent PBRM1 mutations in renal cancer by exon sequencingVarela, Ignacio póster de congreso