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Rights | Preview | Issue Date | Title | Author(s) | Type |
openAccess |  | 2016 | A functional variant of TLR10 modifies the activity of NFkB and may help predict a worse prognosis in patients with rheumatoid arthritis | Torices, Silvia; Varela, Ignacio ; Fernández-Luna, J. L. | artículo |
openAccess |  | 2013 | A genetic progression model of BrafV600E-induced intestinal tumorigenesis reveals targets for therapeutic intervention | Rad, Roland; Varela, Ignacio ; Calvanese, Vincenzo; Bradley, Allan | artículo |
openAccess |  | 2014 | A next-generation dual-recombinase system for time and host specific targeting of pancreatic cancer | Schönhuber, Nina; Varela, Ignacio ; Saur, Dieter | artículo |
closedAccess |  | 2014 | A novel mutation in ADAMTS13 of a child with Upshaw-Schulman Syndrome | Pérez-Rodríguez, A.; Batlle-López, Ana; Blanco, Rosa ; Varela, Ignacio ; León, Javier ; Delgado, M. Dolores ; López-Fernández, M. F. | artículo |
closedAccess |  | 2020 | A spotlight on cancer researchers in Spain: new paradigms and disruptive ideas | Ramón y Cajal, S.; Sancho, P.; Soucek, L.; Peinado, H.; Abad, M.; Valiente, M.; Efeyan, A.; Pardo, J.; Quesada, V.; Jimeno, J.; Duque, P. M.; Antón, A.; Varela, Ignacio ; Schuhmacher, A. J. | editorial |
closedAccess |  | 2016 | Activated KRAS cooperates with MLLAF4 to promote extramedullary engraftment and migration of cord blood CD34+ HSPC but is insufficient to initiate leukemia | Prieto, Cristina ; Agraz-Doblas, Antonio; Varela, Ignacio ; Menendez, Pablo | artículo |
openAccess |  | 2014 | An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge | Brownstein, Catherine A.; Beggs, Alan H.; Barrera, Jorge ; García-Lobo, Juan M. ; González-Lamuño, Domingo; Llorca, Javier; Rodríguez, María Cruz ; Varela, Ignacio ; Kohane, Isaac S.; Margulies, David M. | artículo |
openAccess |  | 2017 | Analysis of the mutational landscape of classic Hodgkin lymphoma identifies disease heterogeneity and potential therapeutic targets | Mata, Elena; Sánchez-Beato, Margarita; Varela, Ignacio ; Piris, Miguel A.; García, Juan F. | artículo |
closedAccess |  | 2020 | Analysis pipelines for cancer genome sequencing in mice | Lange, Sebastian; Engleitner, Thomas; Mueller, Sebastian; Maresch, Roman; Zwiebel, Maximilian; González-Silva, Laura; Schneider, Günter; Banerjee, Ruby; Yang, Fengtang; Vassiliou, George S.; Friedrich, Mathias; Saur, Dieter; Varela, Ignacio ; Rad, Roland | artículo |
openAccess |  | 2020 | Bone marrow clonogenic myeloid progenitors from NPM1-mutated AML patients do not harbor the NPM1 mutation: Implication for the cell-of-origin of NPM1+ AML | Díaz de la Guardia, Rafael; González-Silva, Laura; López-Millán, Belén; Rodríguez-Sevilla, Juan José; Baroni, Matteo L.; Bueno, Clara; Anguita, Eduardo; Vives, Susana; Palomo, Laura; Lapillonne, Helene; Varela, Ignacio ; Menéndez, Pablo | artículo |
openAccess |  | 2019 | CD133-directed CAR T-cells for MLL leukemia: on-target, off-tumor myeloablative toxicity | Bueno, Clara; Velasco-Hernández, Talia ; Gutiérrez-Agüera, Francisco; Zanetti, Samanta Romina; Baroni, Matteo L.; Sánchez-Martínez, Diego; Molina, Oscar; Closa, Adria; Agraz-Doblas, Antonio; Marín, Pedro; Eyras, Eduardo; Varela, Ignacio ; Menendez, Pablo | artículo |
openAccess |  | 2015 | Colorectal adenomas contain multiple somatic mutations that do not coincide with synchronous adenocarcinoma specimens | Vaqué, José P.; Varela, Ignacio ; Moreno, Thaidy; Piris, Miguel A. | artículo |
openAccess |  | 2013 | Detailed molecular characterisation of acute myeloid leukaemia with a normal karyotype using targeted DNA capture | Varela, Ignacio ; Moreno, Teresa ; Rad, Roland; Vassiliou, George S. | artículo |
closedAccess |  | 2016 | Development and validation of a comprehensive genomic diagnostic tool for myeloid malignancies | McKerrell, Thomas; Moreno, Thaidy; Varela, Ignacio ; Vassiliou, George S. | artículo |
closedAccess |  | 2016 | Development of new cell genetic tracing tools for the study of intratumour heterogeneity | Quevedo, Laura; González-Silva, Laura; Moreno, Thaidy; Revilla, Carlos ; Saur, Dieter; Rad, Roland; Varela, Ignacio  | póster de congreso |
openAccess |  | 2014 | Development of synchronous VHL syndrome tumors reveals contingencies and constraints to tumor evolution. | Fisher, Rosalie; Gerlinger, Marco; Varela, Ignacio ; Swanton, Charles | artículo |
openAccess |  | 2016 | Development refractoriness of MLL-rearranged human B cell acute leukemias to reprogramming into pluripotency | Muñoz-López, Alvaro; Prieto, Cristina ; Agraz-Doblas, Antonio; Varela, Ignacio ; Menendez, Pablo | artículo |
closedAccess |  | 26-Sep-2019 | Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs | O’Byrne, Sorcha; Elliott, Natalina; Rice, Siobhan; Buck, Gemma; Fordham, Nicholas; Garnett, Catherine; Godfrey, Laura; Crump, Nicholas T.; Wright, Gary; Inglott, Sarah; Hua, Peng; Psaila, Bethan; Povinelli, Benjamin; Knapp, David J. H. F.; Agraz-Doblas, Antonio; Bueno, Clara; Varela, Ignacio ; Bennett, Phillip; Koohy, Hashem; Watt, Suzanne M.; Karadimitris, Anastasios; Mead, Adam J.; Ancliff, Phillip; Vyas, Paresh; Menéndez, Pablo; Milne, Thomas A.; Roberts, Irene; Roy, Anindita | artículo |
openAccess |  | Jun-2019 | Enhanced hemato-endothelial specification during human embryonic differentiation through developmental cooperation between AF4-MLL and MLL-AF4 fusions | Bueno, Clara; Calero-Nieto, Fernando J.; Wang, Xiaonan; Valdés-Mas, Rafael; Gutiérrez-Agüera, Francisco; Roca-Ho, Heleia; Ayllón, Verónica; Real, Pedro J.; Arambilet, David; Espinosa, Lluis; Torres-Ruiz, Raul; Agraz-Doblas, Antonio; Varela, Ignacio ; Boer, Jasper de; Bigas, Anna; Gottgens, Bertie; Marschalek, Rolf; Menendez, Pablo | artículo |
closedAccess |  | 2017 | Evaluation of Toll-like-receptor gene family variants as prognostic biomarkers in rheumatoid arthritis | Torices, Silvia; Alvarez-Rodríguez, Lorena; Varela, Ignacio ; Muñoz, Pedro; Balsa, Alejandro; López-Hoyos, M.; Martinez-Taboada, Víctor; Fernández-Luna, J. L. | artículo |