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Browsing by Author Rubio, Vicente

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Showing results 1 to 20 of 20
RightsIssue DateTitleAuthor(s)
closedAccess13-Apr-2007A Novel Two-domain Architecture Within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia coli Glutamate 5-kinaseMarco Marín, Clara; Gil-Ortiz, Fernando; Pérez-Arellano, Isabel; Cervera, Javier; Fita, Ignacio; Rubio, Vicente
closedAccessDec-2008Arginine and nitrogen storageLlácer, José Luis; Fita, Ignacio; Rubio, Vicente
closedAccess11-Sep-2014Crystal structures of human carbamoyl phosphate synthetase 1 (CPS1) shed light on domains functions, substrate tunnels and allosteric activation, and allow rationalization of inborn CPS1 deficiencyCima, Sergio de; Polo, Luis Mariano; Díez-Fernández, Carmen; Cervera, Javier; Fita, Ignacio; Rubio, Vicente
closedAccess6-Oct-2006The Gene Cluster for Agmatine Catabolism of Enterococcus faecalis: Study of Recombinant Putrescine Transcarbamylase and Agmatine Deiminase and a Snapshot of Agmatine Deiminase Catalyzing Its ReactionLlácer, José Luis; Polo, Luis Mariano; Tavárez, Sandra; Alarcón, Benito; Hilario, Rebeca; Rubio, Vicente
openAccessMar-2004Happy microbes in hostile niches. A symposium on extremophilesRubio, Vicente
closedAccess19-Jul-2014Human carbamoyl phosphate synthetase: structure, function and pathologyRubio, Vicente; Cima, Sergio de; Polo, Luis Mariano; Díez-Fernández, Carmen; Cervera, Javier; Fita, Ignacio
openAccess18-Apr-2012Insight on an arginine synthesis metabolon from the tetrameric structure of yeast acetylglutamate kinaseCima, Sergio de; Gil-Ortiz, Fernando; Crabeel, Marjolaine; Fita, Ignacio; Rubio, Vicente
openAccess1999N-acetyi-L-glutamate kinase from Escherichia coli: Cloning of the gene, purification and crystallization of the recombinant enzyme and preliminary X-ray analysis of the free and ligand-bound formsGil, Fernando; Ramón-Maiques, Santiago; Marina, Alberto; Fita, Ignacio; Rubio, Vicente
openAccess20-Feb-2012New Insight into the Transcarbamylase Family: The Structure of Putrescine Transcarbamylase, a Key Catalyst for Fermentative Utilization of AgmatinePolo, Luis Mariano; Gil-Ortiz, Fernando; Cantín, Angel; Rubio, Vicente
openAccess8-Feb-2012Structural and functional insights into endoglin ligand recognition and bindingAlt, Aaron; Miguel-Romero, Laura; Donderis, Jordi; Aristorena, Mikel; Blanco, Francisco; Round, Adam; Rubio, Vicente; Bernabéu Quirante, Carmelo; Marina, Alberto
closedAccess24-Feb-2006Structural bases of feed-back control of arginine biosynthesis, revealed by the structures of two hexameric N-acetylglutamate kinases, from Thermotoga maritima and Pseudomonas aeruginosaRamón-Maiques, Santiago; Fernández-Murga, María L.; Gil-Ortiz, Fernando; Vagin, Alexei; Fita, Ignacio; Rubio, Vicente
closedAccess1-Oct-2009Structural insight into partner specificity and phosphoryl transfer in two-component signal transductionCasino, Patricia; Rubio, Vicente; Marina, Alberto
closedAccess2002Structure of acetylglutamate kinase, a key enzyme for arginine biosynthesis and a prototype for the amino acid kinase enzyme family, during catalysisRamón-Maiques, Santiago; Marina, Alberto; Gil-Ortiz, Fernando; Fita, Ignacio; Rubio, Vicente
closedAccess2010Substrate binding and catalysis in carbamate kinase ascertained by crystallographic and site-directed mutagenesis studies: movements and significance of a unique globular subdomain of this key enzyme for fermentative ATP production in bacteriaRamón-Maiques, Santiago; Marina, Alberto; Guinot, Anna; Gil-Ortiz, Fernando; Uriarte, Matxalen; Fita, Ignacio; Rubio, Vicente
openAccess29-May-2012Suggested Guidelines for the Diagnosis and Management of Urea Cycle DisordersHäberle, Johannes; Boddaert, Nathalie; Burlina, Alberto; Chakrapani, Anupam; Dixon, Marjorie; Huemer, Martina; Karall, Daniela; Martinelli, Diego; Crespo, Pablo S.; Santer, René; Servais, Aude; Valayannopoulos, Vassili; Lindner, Martin; Rubio, Vicente; Dionisi-Vici, Carlo
closedAccess2-Jun-2000The 1.5 Å resolution crystal structure of the carbamate kinase-like carbamoyl phosphate synthetase from the hyperthermophilic archaeon Pyrococcus furiosus, bound to ADP, confirms that this thermostable enzyme is a carbamate kinase, and a provides insight into substrate binding and stability in carbamate kinasesRamón-Maiques, Santiago; Marina, Alberto; Uriarte, Matxalen; Fita, Ignacio; Rubio, Vicente
closedAccess1-Aug-2003The course of phosphorus in the reaction of N-Acetyl-L-glutamate kinase, determined from the structures of crystalline complexes, including a complex with an AlF4 - transition state mimicGil-Ortiz, Fernando; Ramón-Maiques, Santiago; Fita, Ignacio; Rubio, Vicente
closedAccess6-Nov-2007The crystal structure of the complex of PII and acetylglutamate kinase reveals how PII controls the storage of nitrogen as arginineLlácer, José Luis; Contreras, Asunción; Forchhammer, Karl; Marco Marín, Clara; Gil-Ortiz, Fernando; Maldonado, R.; Fita, Ignacio; Rubio, Vicente
closedAccess2010Two crystal structures of Escherichia coli N-acetyl-l-glutamate kinase demonstrate the cycling between open and closed conformationsGil-Ortiz, Fernando; Ramón-Maiques, Santiago; Fernández-Murga, María L.; Rubio, Vicente
openAccess18-Apr-2014Understanding carbamoyl phosphate synthetase (CPS1) deficiency by using the recombinantly purified human enzyme: effects of CPS1 mutations that concentrate in a central domain of unknown functionDíez-Fernández, Carmen; Hu, Liyan; Cervera, Javier; Häberle, Johannes; Rubio, Vicente