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Browsing by Author Pera, Benet

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Showing results 1 to 11 of 11
RightsPreviewIssue DateTitleAuthor(s)Type
openAccesstubulin_binding_Coderch.pdf.jpgMar-2013A structure-based design of new C2- and C13-substituted taxanes: Tubulin binding affinities and extended quantitative structure-activity relationships using comparative binding energy (COMBINE) analysisCoderch, Claire; Tang, Yong; Klett, Javier ; Zhang, Shu-En; Ma, Yung-Tao; Shaorong, Wang; Matesanz, Ruth ; Pera, Benet ; Canales, Ángeles ; Jiménez-Barbero, Jesús ; Morreale, Antonio ; Díaz, José Fernando ; Fang, Wei-shuo S.; Gago, Federico Artículo
openAccessJ. Biol. Chem.-2010-Bustamante-33184-96.pdf.jpg22-Oct-2010Cpl-7, a Lysozyme Encoded by a Pneumococcal Bacteriophage with a Novel Cell Wall-Binding MotifBustamante, Noemí ; Campillo, Nuria E. ; García, Ernesto ; Gallego, Cristina; Pera, Benet ; Diakun, Gregory P.; Saiz, José L.; García, Pedro  ; Díaz, José Fernando ; Menéndez, Margarita Artículo
closedAccessrestringido.pdf.jpgJan-2012Cyclostreptin Derivatives Specifically Target Cellular Tubulin and Further Map the Paclitaxel SiteCalvo, Enrique; Barasoain, Isabel ; Matesanz, Ruth ; Pera, Benet ; Camafeita, Emilio; Pineda, Oriol; Hamel, Ernest; Vanderwal, Christopher D.; Andreu, José Manuel ; López, Juan Antonio; Díaz, José Fernando Artículo
openAccessPera et al 2015.pdf.jpg1-Nov-2015High affinity and covalent-binding microtubule stabilizing agents show activity in chemotherapy-resistant acute myeloid leukemia cellsPera, Benet ; Calvo, María Nieves; Ambati, Srikanth; Jordi, Michel; Kahn, Alissa; Díaz, José Fernando ; Fang, Wei-shuo S.; Altmann, Karl-Heinz; Cerchietti, ,Leandro; Moore, Malcolm A. S.Artículo
closedAccess2-May-2011Mechanism of Action of Cytotoxic Macrolides Amphidinolide X and J.Trigili, Chiara ; Pera, Benet ; Barbazanges, Marion; Cossy, Janine; Meyer, Christophe; Pineda, Oriol; Rodríguez-Escrich, Carles; Urpí, Félix; Vilarrasa, Jaume; Díaz, José Fernando ; Barasoain, Isabel Artículo
openAccessMatesanz_et_al_2011 Biophysical Journal.pdf.jpg21-Dec-2011Modulation of microtubule interprotofilament interactions by modified taxanesMatesanz, Ruth ; Rodríguez-Salarichs, Javier; Pera, Benet ; Canales, Ángeles ; Andreu, José Manuel ; Jiménez-Barbero, Jesús ; Bras, Wim; Nogales, Aurora ; Fang, Wei-shuo S.; Díaz, José Fernando Artículo
closedAccess16-Aug-2010Molecular recognition of peloruside A by microtubules. The C24 primary alcohol is essential for biological activity.Pera, Benet ; Razzak, Mina; Trigili, Chiara ; Pineda, Oriol; Canales, Ángeles ; Martínez Buey, Rubén ; Jiménez-Barbero, Jesús ; Northcote, Peter; Paterson, Ian; Barasoain, Isabel ; Díaz, José Fernando Artículo
openAccessMatesanz et al_2014 _Bioorganic Medicinal Chemistry.pdf.jpg19-Jun-2014Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistancesMatesanz, Ruth ; Trigili, Chiara ; Rodríguez-Salarichs, Javier; Pera, Benet ; Jiménez-Barbero, Jesús ; Canales, Ángeles ; Barasoain, Isabel ; Díaz, José Fernando Artículo
openAccessthermodynamics_Matesanz.pdf.jpgNov-2011Thermodynamics as a Tool for the Optimization of Drug Binding, Thermodynamics - Interaction Studies - Solids, Liquids and GasesMatesanz, Ruth ; Pera, Benet ; Díaz, José Fernando Capítulo de libro
openAccessJNP_2017 Field et al.pdf.jpg12-Oct-2017Zampanolide binding to tubulin indicates crosstalk of taxane site with colchicine and nucleotide sitesField, Jessica J.; Pera, Benet ; Estévez Gallego, J.; Rodríguez-Salarichs, Javier; Sáez-Calvo, Gonzalo; Andreu, José Manuel ; Díaz, José Fernando Artículo
openAccessField et al 2012_Chemistry and Biology.pdf.jpg22-Jun-2012Zampanolide, a potent new microtubule stabilizing agent, covalently reacts with the taxane luminal site in both tubulin alpha-beta-heterodimers and microtubulesField, Jessica J.; Pera, Benet ; Calvo, Enrique; Canales, Ángeles ; Zurwerra, Didier; Trigili, Chiara ; Rodríguez-Salarichs, Javier; Matesanz, Ruth ; Kanakkanthara, Arun; Wakefield, St. John; Singh, A. Jonathan; Jiménez-Barbero, Jesús ; Northcote, Peter; Miller, John H.; López, Juan Antonio; Hamel, Ernest; Barasoain, Isabel ; Altmann, Karl-Heinz; Díaz, José Fernando Artículo