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Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
openAccess | | 6-sep-2011 | 1,2,4-tiadiazoles-5-imino sustituidos útiles en el tratamiento de enfermedades neurodegenerativas | Loza García, María Isabel; Martínez Gil, Ana CSIC ORCID ; Pérez, Daniel I. CSIC ORCID; Brea Floriani, José; Cadavid Torres, María Isabel; Palomo, Valle CSIC ORCID ; Gil, Carmen CSIC ORCID ; Pérez Castillo, Ana CSIC ORCID; Pérez, Concepción CSIC ORCID | solicitud de patente |
openAccess | | 14-mar-2018 | 1-(Benzo[d]thiazol-2-yl)-3-phenylureas as dual inhibitors of casein kinase 1 and ABAD enzymes for treatment of neurodegenerative disorders | Benek, O.; Pérez, Daniel I. CSIC ORCID; Pérez, Concepción CSIC ORCID; Martínez Gil, Ana CSIC ORCID ; Musilek, Kamil | artículo |
openAccess | | 14-jul-2015 | 3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the first dual BACE-1/GSK-3β fragment hits against Alzheimer’s disease | Prati, Federica; Pérez, Daniel I. CSIC ORCID; Pérez Castillo, Ana CSIC ORCID; Martínez Gil, Ana CSIC ORCID ; Bolognesi, Maria Laura | artículo |
closedAccess | | 2012 | 5-imino-1,2,4-thiadiazoles: first small molecules as substrate competitive inhibitors of glycogen synthase kinase 3 | Palomo, Valle CSIC ORCID ; Pérez, Daniel I. CSIC ORCID; Pérez, Concepción CSIC ORCID; Morales-García, José A. CSIC ORCID; Soteras, Ignacio CSIC ORCID; Alonso-Gil, Sandra CSIC; Encinas, Arantxa; Castro, Ana CSIC ORCID; Campillo, Nuria E. CSIC ORCID ; Pérez Castillo, Ana CSIC ORCID; Gil, Carmen CSIC ORCID ; Martínez Gil, Ana CSIC ORCID | artículo |
closedAccess | | 2012 | 5-Imino-1,2-4-thiadiazoles and quinazolines derivatives as glycogen synthase kinase 3β (GSK-3β) and phosphodiesterase 7 (PDE7) inhibitors: Determination of blood-brain barrier penetration and binding to human serum albumin | Pérez, Daniel I. CSIC ORCID; Pistolozzi, Marco; Redondo, Miriam CSIC; Fortugno, Cecilia; Gil, Carmen CSIC ORCID ; Felix, Guy; Martínez Gil, Ana CSIC ORCID ; Bertucci, Carlo | artículo |
closedAccess | | 2013 | A fluorescent styrylquinoline with combined therapeutic and diagnostic activities against Alzheimer's and prion diseases | Staderini, Matteo; Aulic, Suzana; Bartolini, Manuela; Tran, H. N. A.; González-Ruiz, Victor; Pérez, Daniel I. CSIC ORCID; Cabezas, Nieves; Martínez Gil, Ana CSIC ORCID ; Martín, M. Antonia; Andrisano, Vincenza; Legname, Giuseppe; Menéndez, José Carlos; Bolognesi, Maria Laura | artículo |
closedAccess | | 2012 | A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: Structure-based design, synthesis, and biological evaluation | Chiriano, G.; De Simone, A.; Mancini, Francesca; Pérez, Daniel I. CSIC ORCID; Cavalli, A.; Bolognesi, Maria Laura; Legname, G.; Martínez, A.; Andrisano, Vincenza; Carloni, Paolo; Roberti, M. | artículo |
openAccess | | mar-2016 | Application of BACE1 immobilized enzyme reactor for the characterization of multifunctional alkaloids from Corydalis cava (Fumariaceae) as Alzheimer's disease targets | Chlebek, Jakub; De Simone, Angela; Hošťálková, Anna; Opletal, Lubomír; Pérez, Concepción CSIC ORCID; Pérez, Daniel I. CSIC ORCID; Havlíková, Lucie; Cahlíková, Lucie; Andrisano, Vincenza | artículo |
openAccess | | 1-sep-2014 | Benzotiazoles sustituidos y sus aplicaciones terapéuticas para el tratamiento de enfermedades humanas | Martínez Gil, Ana CSIC ORCID ; Pérez, Daniel I. CSIC ORCID; Gil, Carmen CSIC ORCID ; García Salado, Irene; Redondo, Miriam CSIC; Pérez, Concepción CSIC ORCID | solicitud de patente |
openAccess | | 1-sep-2014 | Benzotiazoles sustituidos y sus aplicaciones terapéuticas para el tratamiento de enfermedades humanas | Martínez Gil, Ana CSIC ORCID ; Pérez, Daniel I. CSIC ORCID; Gil, Carmen CSIC ORCID ; García Salado, Irene; Redondo, Miriam CSIC; Pérez, Concepción CSIC ORCID | patente |
openAccess | | 15-nov-2022 | Bifunctional carbazole derivatives for simultaneous therapy and fluorescence imaging in prion disease murine cell models | Staderini, Matteo; Vanni, Silvia; Colini Baldeschi, Arianna; Giachin, Gabriele; Zattoni, Marco; Celauro, Luigi; Ferracin, Chiara; Bistaffa, Edoardo; Moda, F.; Pérez, Daniel I. CSIC ORCID; Martínez Gil, Ana CSIC ORCID ; Martín, M. Antonia; Martín-Cámara, Olmo; Cores, Ángel; Bianchini, Giulia; Kammerer, Robert; Menéndez, J. Carlos; Legname, G.; Bolognesi, Maria Laura | artículo |
openAccess | | 30-ago-2017 | Biological and pharmacological characterization of benzothiazole-based CK-1δ inhibitors in models of Parkinson’s disease | Morales-García, José A. CSIC ORCID; Salado, Irene G. CSIC; Sanz-SanCristóbal, Marina CSIC; Gil, Carmen CSIC ORCID ; Pérez Castillo, Ana CSIC ORCID; Martínez Gil, Ana CSIC ORCID ; Pérez, Daniel I. CSIC ORCID | artículo |
openAccess | | 26-mar-2020 | CDC-7-inhibitors compounds and use thereof for the treatment of neurological conditions | Martínez Gil, Ana CSIC ORCID ; Pérez, Daniel I. CSIC ORCID; Gil, Carmen CSIC ORCID ; Martín-Requero, Ángeles CSIC ORCID ; Rojas-Prats, Elisa CSIC ORCID; Martínez-González, Loreto CSIC ORCID ; Pérez, Concepción CSIC ORCID | solicitud de patente |
openAccess | | 5-feb-2020 | CDC-7-inhibitors compounds and use thereof for the treatment of neurological conditions | Martínez Gil, Ana CSIC ORCID ; Pérez, Daniel I. CSIC ORCID; Gil, Carmen CSIC ORCID ; Martín-Requero, Ángeles CSIC ORCID ; Rojas-Prats, Elisa CSIC ORCID; Martínez-González, Loreto CSIC ORCID ; Pérez, Concepción CSIC ORCID | solicitud de patente |
openAccess | | 27-sep-2018 | CDC-7-inhibitors compounds and use thereof for the treatment of neurological conditions | Martínez Gil, Ana CSIC ORCID ; Pérez, Daniel I. CSIC ORCID; Gil, Carmen CSIC ORCID ; Martín-Requero, Ángeles CSIC ORCID ; Rojas-Prats, Elisa CSIC ORCID; Martínez-González, Loreto CSIC ORCID ; Pérez, Concepción CSIC ORCID | solicitud de patente |
closedAccess | | 2018 | Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitors | Chierrito, Talita P. C.; Pedersoli-Mantoani, S.; Roca, Carlos CSIC ORCID; Sebastián-Pérez, Víctor; Martínez-González, Loreto CSIC ORCID ; Pérez, Daniel I. CSIC ORCID; Pérez, Concepción CSIC ORCID; Canales, Ángeles CSIC ORCID; Cañada, F. Javier ; Campillo, Nuria E. CSIC ORCID ; Carvalho, Ivone; Martínez Gil, Ana CSIC ORCID | artículo |
openAccess | | 10-jul-2003 | Compounds and their therapeutic use related to the phophorylating activity of the enzyme GSK-3 | Conde, Santiago CSIC; Martínez Gil, Ana CSIC ORCID ; Pérez, Daniel I. CSIC ORCID; Pérez, Concepción CSIC ORCID; Moreno Muñoz, Francisco José; Wandosell, Francisco CSIC ORCID | patente |
openAccess | | 22-oct-2018 | Compuestos inhibidores de CDC-7 y su uso para el tratamiento de patologías neurológicas | Martínez Gil, Ana CSIC ORCID ; Pérez, Daniel I. CSIC ORCID; Gil, Carmen CSIC ORCID ; Martín-Requero, Ángeles CSIC ORCID ; Rojas-Prats, Elisa CSIC ORCID; Martínez-González, Loreto CSIC ORCID ; Pérez, Concepción CSIC ORCID | patente |
openAccess | | 22-oct-2018 | Compuestos inhibidores de CDC-7 y su uso para el tratamiento de patologías neurológicas | Martínez Gil, Ana CSIC ORCID ; Pérez, Daniel I. CSIC ORCID; Gil, Carmen CSIC ORCID ; Martín-Requero, Ángeles CSIC ORCID ; Rojas-Prats, Elisa CSIC ORCID; Martínez-González, Loreto CSIC ORCID ; Pérez, Concepción CSIC ORCID | solicitud de patente |
openAccess | | 1-ene-2019 | Computer-aided molecular design of pyrazolotriazines targeting glycogen synthase kinase 3 | Sciú, María Lourdes; Sebastián-Pérez, Víctor; Martínez-González, Loreto CSIC ORCID ; Benítez, Rocio; Pérez, Daniel I. CSIC ORCID; Pérez, Concepción CSIC ORCID; Campillo, Nuria E. CSIC ORCID ; Martínez Gil, Ana CSIC ORCID ; Moyano, Elizabeth Laura | artículo |