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Browsing by Author Pérez, Daniel I.

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openAccessacs chem. neur._Martínez, Ana_2015(post).pdf.jpg14-Jul-20153,4-Dihydro-1,3,5-triazin-2(1H)-ones as the first dual BACE-1/GSK-3β fragment hits against Alzheimer’s diseasePrati, Federica; Pérez, Daniel I.; Pérez Castillo, Ana ; Martínez, Ana ; Bolognesi, Maria Lauraartículo
closedAccessaccesoRestringido.pdf.jpg20125-imino-1,2,4-thiadiazoles: first small molecules as substrate competitive inhibitors of glycogen synthase kinase 3Palomo Ruiz, Valle; Pérez, Daniel I.; Pérez, Concepción; Morales-García, José A. ; Soteras, Ignacio ; Alonso-Gil, Sandra ; Encinas, Arantxa; Castro, Ana ; Campillo, Nuria E. ; Pérez Castillo, Ana ; Gil, Carmen  ; Martínez, Ana artículo
closedAccessaccesoRestringido.pdf.jpg2013A fluorescent styrylquinoline with combined therapeutic and diagnostic activities against Alzheimer's and prion diseasesStaderini, Matteo; Aulic, Suzana; Bartolini, Manuela; Tran, H. N. A.; González-Ruiz, Victor; Pérez, Daniel I.; Cabezas, Nieves; Martínez, Ana ; Martín, M. Antonia; Andrisano, Vincenza; Legname, Giuseppe; Menéndez, J. Carlos; Bolognesi, Maria Lauraartículo
openAccessFitoterapia postprint-1.pdf.jpgMar-2016Application of BACE1 immobilized enzyme reactor for the characterization of multifunctional alkaloids from Corydalis cava (Fumariaceae) as Alzheimer's disease targetsChlebek, Jakub; De Simone, Angela; Hošťálková, Anna; Opletal, Lubomír; Pérez, Concepción; Pérez, Daniel I.; Havlíková, Lucie; Cahlíková, Lucie; Andrisano, Vincenzaartículo
openAccessacsomega.7b00869.pdf.jpg30-Aug-2017Biological and pharmacological characterization of benzothiazole-based CK-1δ inhibitors in models of Parkinson’s diseaseMorales-García, José A. ; Salado, Irene G. ; Sanz-SanCristóbal, Marina ; Gil, Carmen  ; Pérez Castillo, Ana ; Martínez, Ana ; Pérez, Daniel I.artículo
closedAccessaccesoRestringido.pdf.jpg2018Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitorsChierrito, Talita P. C.; Pedersoli-Mantoani, S.; Roca, Carlos; Sebastián-Pérez, Víctor; Martínez-González, Loreto; Pérez, Daniel I.; Pérez, Concepción; Canales, A.; Cañada, F. Javier ; Campillo, Nuria E. ; Carvalho, Ivone; Martínez, Ana artículo
openAccessES2391732A1.pdf.jpg29-Nov-2012Derivados heterocíclicos inhibidores de fosfodiesterasa 7Gil, Carmen  ; Martínez, Ana ; Redondo, Miriam ; Campillo, Nuria E. ; Pérez, Daniel I.; Loza, María Isabel; Cadavid, María Isabel; Brea, José; Pérez Castillo, Ana solicitud de patente
openAccessEOID_Postprint_2017.pdf.jpgApr-2017Drugs on clinical development for the treatment of amyotrophic lateral sclerosisMartínez, Ana ; Palomo Ruiz, Valle; Pérez, Daniel I.; Gil, Carmen  artículo
openAccessEffect of phosphodiesterase.pdf.jpg2012Effect of phosphodiesterase 7 (PDE7) inhibitors in experimental autoimmune encephalomyelitis mice. Discovery of a new chemically diverse family of compoundsRedondo, Miriam ; Brea, José; Pérez, Daniel I.; Soteras, Ignacio ; Val, Cristina; Pérez, Concepción; Morales-García, José A. ; Alonso-Gil, Sandra ; Paul-Fernández, Nuria ; Martín-Álvarez, Rocío ; Cadavid, María Isabel; Loza, María Isabel; Pérez Castillo, Ana ; Mengod Los Arcos, Guadalupe ; Campillo, Nuria E. ; Martínez, Ana ; Gil, Carmen  artículo
openAccess2015From bitopic inhibitors to multitarget drugs for Alzheimer’s disease future treatmentPérez, Daniel I.; Martínez, Ana ; Gil, Carmen  ; Campillo, Nuria E. artículo
closedAccessaccesoRestringido.pdf.jpg2013Glycogen synthase kinase-3 inhibitors as potent therapeutic agents for the treatment of Parkinson diseaseMorales-García, José A. ; Susín, Cristina ; Alonso-Gil, Sandra ; Pérez, Daniel I.; Palomo Ruiz, Valle; Pérez, Concepción; Conde, Santiago ; Santos, Ángel; Gil, Carmen  ; Martínez, Ana ; Pérez Castillo, Ana artículo
openAccessmolecules-24-01340.pdf.jpg5-Apr-2019In Vitro and In Silico Acetylcholinesterase Inhibitory Activity of Thalictricavine and Canadine and Their Predicted Penetration across the Blood-Brain BarrierChlebek, Jakub; Korábečný, Jan; Doležal, Rafael; Štěpánková, Šárka; Pérez, Daniel I.; Hošťálková, Anna; Opletal, Lubomír; Cahlíková, Lucie; Macáková, Kateřina; Kučera, Tomáš; Hrabinová, Martina; Jun, Danielartículo
openAccessEuropean J. Medicinal Chemistry 2017.pdf.jpg29-Sep-2017Leucine rich repeat kinase 2 (LRRK2) inhibitors based on indolinone scaffold: Potential pro-neurogenic agentsSalado, Irene G. ; Zaldívar-Díez, Josefa; Sebastián-Pérez, Víctor; Li, Lingling; Geiger, Larissa; González, Silvia; Campillo, Nuria E. ; Gil, Carmen  ; Morales, Aixa V. ; Pérez, Daniel I.; Martínez, Ana artículo
closedAccessaccesoRestringido.pdf.jpg2012Microwave-assisted synthesis of hydroxyphenyl nitrones with protective action against oxidative stressChavarría, Cecilia; Pérez, Daniel I.; Pérez, Concepción; Morales-García, José A. ; Alonso-Gil, Sandra ; Pérez Castillo, Ana ; Gil, Carmen  ; Souza, José M.; Porcal, Williamsartículo
closedAccessaccesoRestringido.pdf.jpg2014Modulation of cAMP-specific PDE without emetogenic activity: New sulfide-like PDE7 inhibitorsGarcía, Ana M. ; Brea, José; Morales-García, José A. ; Pérez, Daniel I.; González, A. ; Alonso-Gil, Sandra ; Conde, Santiago ; Cadavid, María Isabel; Loza, María Isabel; Pérez Castillo, Ana ; Martínez, Ana ; Gil, Carmen  artículo
closedAccessaccesoRestringido.pdf.jpg2015Multitarget drug discovery for Alzheimer's disease: Triazinones as BACE-1 and GSK-3ß inhibitorsPérez, Daniel I.; Pérez Castillo, Ana ; Martínez, Ana ; Bolognesi, Maria Laura; Cavalli, Andreaartículo
closedAccessaccesoRestringido.pdf.jpg2015Neuroprotection of CK-1 inhibitors against TDP-43 and LPS toxicityMartínez, Ana ; Pérez, Daniel I.; Salado, Irene G. ; Gil, Carmen  ; Morales-García, José A. ; Pérez Castillo, Ana comunicación de congreso
closedAccessaccesoRestringido.pdf.jpg2012Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke modelRedondo, Miriam ; Zarruk, Juan G.; Ceballos, Placido ; Pérez, Daniel I.; Pérez Martín, María Concepción; Pérez Castillo, Ana ; Moro, María A.; Brea, José; Val, Cristina; Cadavid, María Isabel; Loza, María Isabel; Campillo, Nuria E. ; Martínez, Ana ; Gil, Carmen  artículo
openAccessEJMECH_N. Campillo.pdf.jpg30-Jun-2016New applications for known drugs: Human glycogen synthase kinase 3 inhibitors as modulators of Aspergillus fumigatus growthSebastián-Pérez, Víctor; Manoli, Maria-Tsampika; Pérez, Daniel I.; Gil, Carmen  ; Mellado, Emilia; Martínez, Ana ; Espeso, Eduardo A. ; Campillo, Nuria E. artículo
closedAccess2017Pharmacological tools based on imidazole scaffold proved the utility of PDE10A inhibitors for Parkinson’s diseaseGarcía, Ana M. ; Salado, Irene G. ; Pérez, Daniel I.; Brea, José; Morales-García, José A. ; González-García, Alejandro; Cadavid, María Isabel; Loza, María Isabel; Luque, Francisco Javier; Pérez Castillo, Ana ; Martínez, Ana ; Gil, Carmen  artículo