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Browsing by Author Lacal, Juan Carlos

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RightsPreviewIssue DateTitleAuthor(s)Type
openAccess18F-choline.pdf.jpgMar-200618F-choline images murine atherosclerotic plaques ex vivoMatter, Christian M.; Wyss, Matthias T.; Meier, Patricia; Lohmann, Christine; Weber, Bruno; Ramírez de Molina, Ana; Ametamey, Simon M.; Lacal, Juan Carlos ; Kaufmann, Philipp A.; Buck, AlfredArtículo
closedAccessaccesoRestringido.pdf.jpg2012Acid ceramidase as a chemotherapeutic target to overcome resistance to the antitumoral effect of choline kinase α inhibitionRamírez de Molina, Ana; Cueva, Ana de la; Machado-Pinilla, R. ; Rodriguez-Fanjul, V. ; Gómez del Pulgar, Teresa; Cebrián, Arancha; Perona Abellón, Rosario ; Lacal, Juan Carlos Artículo
openAccesskinases in Xenopus.pdf.jpgFeb-1995Activation of intracellular kinases in Xenopus oocytes by p21ras and phospholipases: a comparative studyCarnero, Amancio ; Lacal, Juan Carlos Artículo
closedAccessaccesoRestringido.pdf.jpg1-Mar-1997Activation of phospholipase D by growth factors and oncogenes in murine fibroblasts follow alternative but cross-talking pathwaysPeso, Luis del; Lucas, Luisa; Esteve, Pilar ; Lacal, Juan Carlos Artículo
closedAccessaccesoRestringido.pdf.jpg1999Activation of serum response factor by RhoA is mediated by the nuclear factor-κB and C/EBP transcription factorsMontaner, Silvia; Perona Abellón, Rosario ; Saniger, Luisa; Lacal, Juan Carlos Artículo
openAccessWO2007138143A2.pdf.jpg6-Dec-2007Alpha anticholine kinase monoclonal antibodies and their use in analytical techniques for the diagnosis of cancer and the preparation of medicinal productsRamírez de Molina, Ana; Gallego Ortega, David ; Lacal, Juan Carlos Patente
openAccessApoptosis induced.pdf.jpgDec-2000Apoptosis induced by Rac GTPase correlates with induction of FasL and ceramides productionEmbade, Nieves; Valerón, Pilar F.; Aznar, Salvador; López-Collazo, Eduardo; Lacal, Juan Carlos Artículo
closedAccessaccesoRestringido.pdf.jpg2011Approaches for the study of cancer: towards the integration of genomics, proteomics and metabolomicsCasado-Vela, Juan; Cebrián, Arancha; Gómez del Pulgar, Teresa; Lacal, Juan Carlos Artículo
openAccess2933.pdf.jpgAug-2002Cell stress and MEKK1-mediated c-Jun activation modulate NFkappaB activity and cell viabilitySánchez-Pérez, Isabel; Aznar, Salvador; Martínez-Gomariz, Montserrat; Lacal, Juan Carlos ; Perona Abellón, Rosario Artículo
openAccessChanging the course of oncogenesis.pdf.jpg2006Changing the course of oncogenesis: The development of tyrosine kinase inhibitorsLacal, Juan Carlos Artículo
closedAccessDec-2008Choline kinase alpha depletion selectively kills tumoral cellsBáñez Coronel, Mónica; Ramírez de Molina, Ana; Rodríguez-González, Agustín; Sarmentero, Jacinto; Ramos, Mª Angeles; García Cabezas, Miguel Ángel; Garcia-Oroz, Lourdes; Lacal, Juan Carlos Artículo
openAccesscddis2013. T. Zimmerman.pdf.jpg28-Nov-2013Choline kinase inhibition induces exacerbated endoplasmic reticulum stress and triggers apoptosis via CHOP in cancer cellsSánchez-López, E.; Zimmerman, T.; Gómez del Pulgar, Teresa; Moyer, M.P.; Lacal, Juan Carlos ; Cebrián, AranchaArtículo
closedAccessaccesoRestringido.pdf.jpg2004Choline kinase inhibition induces the increase in ceramides resulting in a highly specific and selective cytotoxic antitumoral strategy as a potential mechanism of actionRodríguez-González, Agustín; Ramírez de Molina, Ana; Fernández, Félix; Lacal, Juan Carlos Artículo
closedAccessaccesoRestringido.pdf.jpg2005Choline kinase is a novel oncogene that potentiates RhoA-induced carcinogenesisRamírez de Molina, Ana; Gallego Ortega, David ; Sarmentero Estrada, Jacinto; Báñez Coronel, Mónica; Martín, Yolanda; Lacal, Juan Carlos Artículo
openAccessMouse Xenografts.pdf.jpg2013Combined 5-FU and ChoKα inhibitors as a new alternative therapy of colorectal cancer: Evidence in human tumor-derived cell lines and mouse xenograftsCueva, Ana de la; Ramírez de Molina, Ana; Álvarez-Ayerza, Nestor; Ramos, Maria Angeles ; Cebrián, Arancha; Gómez del Pulgar, Teresa; Lacal, Juan Carlos Artículo
openAccessWO2015028662_A1.pdf.jpg5-Mar-2015Compositions and methods for characterization and amelioration of rheumatoid arthritisFirestein, Gary S.; Guma, Mónica; Karin, Michael; Sánchez-López, Elsa; Lacal, Juan Carlos ; Tiziani, StefanoPatente
openAccess2277568_B1.pdf.jpg1-Apr-2008Derivados de triterpenoquinonas y triterpenofenoles y su aplicación para el tratamiento de tumores y enfermedades parasitariasLacal, Juan Carlos ; Ramírez de Molina, Ana; Báñez Coronel, Mónica; Gutiérrez Ravelo, Ángel; Estévez-Braun, Ana; Mesa Siverio, Dulce Y.; Pérez Sacau, ElisaPatente
openAccessEP1710236A1-1.pdf.jpg15-Apr-2010Derivatives of pyridine and quinolineLacal, Juan Carlos ; Campos Rosa, Joaquín M.; Gallo Meza, Miguel Angel; Espinosa Ubeda, AntonioSolicitud de patente
openAccessWO2004016622A1.pdf.jpg26-Feb-2004´Derivatives of4-4'-BIPYRIDYL-2-2'-BISOXAZOLES AND 4-4'-BIPYRIDYL-2-2'-BISTIAZOLES as antineoplastic agents.Martín, Yolanda; Villa Hormaeche, Maria Jesus; Saez Pizarro, Beatriz; Soto Romero, Javier; Fernández, M.  ; Lacal, Juan Carlos Patente
closedAccessaccesoRestringido.pdf.jpg1990Diacylglycerol production in Xenopus laevis oocytes after microinjection of p21ras proteins is a consequence of activation of phosphatidylcholine metabolismLacal, Juan Carlos Artículo