Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
openAccess | | 6-dic-2021 | CLIP-170S is a microtubule +TIP variant that confers resistance to taxanes by impairing drug-target engagement | Thakkar, Prashant V.; Kita, Katsuhiro; Del Castillo, Urko; Galletti, Giuseppe; Madhukar, Neel; Vila Navarro, Elena; Barasoain, Isabel CSIC ; Goodson, Holly V.; Sackett, Dan L.; Díaz, José Fernando CSIC ORCID ; Lu, Yao CSIC ORCID; RoyChoudhary, Arindam; Molina, Henrik; Elemento, Olivier; Shah, Manish A.; Giannakakou, Paraskevi | artículo |
closedAccess | | 30-ago-2005 | Cyclostreptin (FR182877), an Antitumour Tubulin-Polymerizing Agent Deficient in Enhancing Tubulin Assembly Despite Its High Affinity for the Taxoid Site | Edler, Michael C.; Martínez Buey, Rubén CSIC ORCID; Gussio, Rick; Marcus, Adam I.; Vanderwal, Christopher D.; Sorensen, Erik J.; Díaz, José Fernando CSIC ORCID ; Giannakakou, Paraskevi; Hamel, Ernest | artículo |
closedAccess | | 1-sep-2006 | Farnesyl transferase inhibitors reverse taxane-resistence | Marcus, Adam I.; O'Brate, Aurora M.; Martínez Buey, Rubén CSIC ORCID; Zhou, Jun; Thomas, Shala; Khuri, Fadlo R.; Andreu, José Manuel CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Giannakakou, Paraskevi | artículo |
closedAccess | | feb-2004 | Interaction of Epothilone Analogs with the Paclitaxel Binding Site: Relationship between Binding Affinity, Microtubule Stabilization, and Cytotoxicity | Martínez Buey, Rubén CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Andreu, José Manuel CSIC ORCID ; O´Brate, Aurora M.; Giannakakou, Paraskevi; Nicolaou, K.C.; Sasmal, Pradip K.; Ritzen, Andreas; Namoto, Kenji | artículo |
closedAccess | | 2005 | Microtubule interactions with chemically diverse stabilizing agents: Thermodynamics of binding to the paclitaxel site predicts cytotoxicity | Martínez Buey, Rubén CSIC ORCID; Barasoain, Isabel CSIC ; Jackson, Evelyn; Meyer, Arndt; Giannakakou, Paraskevi; Paterson, Ian; Mooberry, Susan; Andreu, José Manuel CSIC ORCID ; Díaz, José Fernando CSIC ORCID | artículo |
closedAccess | | jul-2019 | Systems biology identifies that Gleevec reverses taxane resistance in solid tumors by selective inhibition of a novel plus Tip microtubule-binding variant | Thakkar, Prashant V.; Kita, Katsuhiro; Galletti, Giuseppe; Madhukar, Neel; Cleveland, Kyle; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Elemento, Olivier; Shah, Manish A.; Giannakakou, Paraskevi | comunicación de congreso |