Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
closedAccess | | 18-jun-2018 | 5-Hydroxypyrido[2,3-b]pyrazin-6(5H)-one derivatives as novel dual inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H and integrase | Sun, Lin; Gao, Ping; Dong, Guanyu; Zhang, Xujie; Ding, Xiao; Wang, Xueshun; Daelemans, Dirk; De Clercq, Erik; Pannecouque, Christophe; Menéndez-Arias, Luis CSIC ORCID ; Zhang, Peng; Liu, Xinyong | artículo |
closedAccess | | 1998 | Abasic analogues of TSAO-T as the first sugar derivatives that specifically inhibit HIV-1 reverse transcriptase | Velázquez, Sonsoles CSIC ORCID CVN; Chamorro, Cristina CSIC; Peréz-Pérez, María-Jesús CSIC ORCID ; Álvarez, Rosa; Jimeno, M. Luisa CSIC ORCID; Martín Domenech, Angel; Pérez, Carlos; Gago, Federico CSIC ORCID; De Clercq, Erik; Balzarini, Jan; San-Félix, Ana CSIC ORCID ; Camarasa Rius, María José CSIC ORCID | artículo |
closedAccess | | feb-1993 | Activity of several S-adenosylhomocysteine hydrolase inhibitors against African swine fever virus replication in Vero cells | Villalón, M.; Gil-Fernández, Carmen ; De Clercq, Erik | artículo |
closedAccess | | 2001 | Anti-HIV-1 activity of benzothiadiazine dioxide | Martínez Gil, Ana CSIC ORCID ; Gil, Carmen CSIC ORCID ; Castro, Ana CSIC ORCID; Pérez, Concepción CSIC ORCID; Witvrouw, M.; Pannecouque, C.; Balzarini, Jan; De Clercq, Erik | artículo |
openAccess | | 1-sep-2019 | Design, synthesis and biological evaluation of 3-hydroxyquinazoline-2,4(1H,3H)-diones as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and integrase | Gao, Ping; Cheng, Xiqiang; Sun, Lin; Song, Shu; Álvarez, Mar CSIC ORCID; Luczkowiak, Joanna; Pannecouque, Christophe; De Clercq, Erik; Menéndez-Arias, Luis CSIC ORCID ; Zhan, Peng; Liu, Xinyong | artículo |
openAccess | | 24-nov-2018 | Design, synthesis, and biologic evaluation of novel galloyl derivatives as HIV-1 RNase H inhibitors | Gao, Ping; Sun, Lin; Cheng, Xiqiang; Poongavanam, Vasanthanathan; Kongsted, Jacob; Álvarez, Mar CSIC ORCID; Luczkowiak, Joanna; Pannecouque, Christophe; De Clercq, Erik; Lee, Kuo-Hsiung; Chen, Chin-Ho; Liu, Huiqing; Menéndez-Arias, Luis CSIC ORCID ; Liu, Xinyong; Zhang, Peng | artículo |
openAccess | | 2021 | Discovery, optimization, and target identification of novel coumarin derivatives as HIV-1 reverse transcriptase-associated ribonuclease H inhibitors | Kang, Dongwei; Urhan, Çagil; Wei, Fenju; Frutos-Beltrán, Estrella CSIC ORCID; Sun, Lin; Álvarez, Mar CSIC ORCID; Feng, Da; Tao, Yucen; Pannecouque, Christophe; De Clercq, Erik; Menéndez-Arias, Luis CSIC ORCID ; Liu, Xinyong; Zhan, Peng | artículo |
closedAccess | | 2000 | HIV-1 specific reverse transcriptase inhibitors: Why are TSAO-nucleosides so unique? | Camarasa Rius, María José CSIC ORCID; San-Felix, Alejandra; Peréz-Pérez, María-Jesús CSIC ORCID ; Velázquez, Sonsoles CSIC ORCID CVN; Álvarez, Rosa; Chamorro, Cristina CSIC; Jimeno, M. Luisa CSIC ORCID; Perez, Carlos; Gago, Federico CSIC ORCID; De Clercq, Erik; Balzarini, Jan | artículo |
openAccess | | 17-feb-2021 | Medicinal chemistry strategies for discovering antivirals effective against drug-resistant viruses | Ma, Yue; Frutos-Beltrán, Estrella CSIC ORCID; Kang, Dongwei; Pannecouque, Christophe; De Clercq, Erik; Menéndez-Arias, Luis CSIC ORCID ; Liu, Xinyong; Zhan, Peng | artículo de revisión |
openAccess | | 17-feb-2021 | Medicinal chemistry strategies for discovering antivirals effective against drug-resistant viruses | Ma, Yue; Frutos-Beltrán, Estrella CSIC ORCID; Kang, Dongwei; Pannecouque, Christophe; De Clercq, Erik; Menéndez-Arias, Luis CSIC ORCID ; Liu, Xinyong; Zhan, Peng | artículo de revisión |
openAccess | | 17-feb-2021 | Medicinal chemistry strategies for discovering antivirals effective against drug-resistant viruses | Ma, Yue; Frutos-Beltrán, Estrella CSIC ORCID; Kang, Dongwei; Pannecouque, Christophe; De Clercq, Erik; Menéndez-Arias, Luis CSIC ORCID ; Liu, Xinyong; Zhan, Peng | artículo de revisión |
closedAccess | | 2000 | Nonnucleoside human cytomegalovirus inhibitors: Synthesis and antiviral evaluation of (chlorophenylmethyl)benzothiadiazine dioxide derivatives | Martínez Gil, Ana CSIC ORCID ; Gil, Carmen CSIC ORCID ; Pérez, Concepción CSIC ORCID; Castro, Ana CSIC ORCID; Prieto, Columbiana; Otero, Joaquín; Andrei, G; Snoeck, R.; Balzarini, Jan; De Clercq, Erik | artículo |
closedAccess | | 1997 | Novel analogues of the anti HIV-1 agent TSAO-T modified at the 3'-spiro moiety | Álvarez, Rosa; Jimeno, M. Luisa CSIC ORCID; De Clercq, Erik; Balzarini, Jan; Camarasa Rius, María José CSIC ORCID | artículo |
openAccess | | 12-oct-2020 | Novel indolylarylsulfone derivatives as covalent HIV-1 reverse transcriptase inhibitors specifically targeting the drug-resistant mutant Y181C | Gao, Ping; Song, Shu; Frutos-Beltrán, Estrella CSIC ORCID; Li, Wenxin; Sun, Bin; Kang, Dongwei; Zou, Jinmi; Zhang, Jian; Pannecouque, Christophe; De Clercq, Erik; Menéndez-Arias, Luis CSIC ORCID ; Zhan, Peng; Liu, Xinyong | artículo |
closedAccess | | 1999 | Potential multifunctional inhibitors of HIV-1 reverse transcriptase. Novel [AZT]-[TSAO-T] and [d4T]-[TSAO-T] heterodimers modified in the linker and in the dideoxynucleoside region | Velázquez, Sonsoles CSIC ORCID CVN; Tuñón, Victoria; Jimeno, M. Luisa CSIC ORCID; Chamorro, Cristina CSIC; De Clercq, Erik; Balzarini, Jan; Camarasa, María José | artículo |
closedAccess | | 2001 | Second generation of TSAO compounds directed against HIV-1 TSAO-resistant strains | Lobaton, E.; Velázquez, Sonsoles CSIC ORCID CVN; Peréz-Pérez, María-Jesús CSIC ORCID ; Jimeno, M. Luisa CSIC ORCID; San-Felix, S.; De Clercq, Erik; Balzarini, Jan; Camarasa Rius, María José CSIC ORCID | artículo |
closedAccess | | 1995 | Synthesis and Anti-HIV Activity of [UT]-[TSAO-TI and [UT]-[HEPT] Dimers as Potential Multifunctional Inhibitors of HIV-1 Reverse Transcriptase | Velázquez, Sonsoles CSIC ORCID CVN; Álvarez, Rosa; San-Félix, Ana CSIC ORCID ; Jimeno, M. Luisa CSIC ORCID; De Clercq, Erik; Camarasa Rius, María José CSIC ORCID | artículo |
closedAccess | | 1998 | Synthesis and anti-HIV properties of 1,2,4,6-thiatriazin-3-one 1,1-dioxide nucleosides | Ochoa, Carmen; Provencio, Rafael; Jimeno, M. Luisa CSIC ORCID; Balzarini, Jan; De Clercq, Erik | artículo |
closedAccess | | 1997 | Synthesis and anti-human immunodeficiency virus type 1 activity of novel 3'-spiro nucleoside analogues of TSAO-T | Álvarez, Rosa; Jimeno, M. Luisa CSIC ORCID; Peréz-Pérez, María-Jesús CSIC ORCID ; De Clercq, Erik; Balzarini, Jan; Camarasa Rius, María José CSIC ORCID | artículo |