Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
openAccess | | 2022 | A Plurizyme with Transaminase and Hydrolase Activity Catalyzes Cascade Reactions | Roda, Sergi; Fernández-López, Laura; Benedens, Marius; Bollinger, Alexander; Thies, Stephan; Schumacher, Julia; Coscolín, Cristina CSIC ORCID; Kazemi, Masoud; Santiago, Gerard; Gertzen, Christoph G. W.; González-Alfonso, José L.; Plou Gasca, Francisco José CSIC ORCID ; Jaeger, Karl-Erich; Ferrer, Manuel CSIC ORCID; Guallar, Victor | artículo |
openAccess | | 23-may-2016 | Asymmetric sulfoxidation by engineering the heme pocket of a dye-decolorizing peroxidase | Linde, Dolores CSIC ORCID ; Cañellas, Marina; Coscolín, Cristina CSIC ORCID; Davó-Siguero, Irene CSIC; Romero, Antonio CSIC ORCID ; Lucas, Fátima; Ruiz-Dueñas, F. J. CSIC ORCID ; Guallar, Victor; Martínez, Ángel T. CSIC ORCID | artículo |
openAccess | | 2019 | Bioprospecting Reveals Class III omega-Transaminases ConvertingBulky Ketones and Environmentally Relevant Polyamines | Coscolín, Cristina CSIC ORCID; Katzke, Nadine; García-Moyano, Antonio; Navarro-Fernández, José; Almendral, David CSIC ORCID; Martínez-Martínez, Mónica CSIC ORCID; Bollinger, Alexander; Bargiela, Rafael CSIC ORCID; Gertler, Christoph; Chernikova, Tatyana; Rojo, David; Barbas, Coral; Tran, Hai; Golyshina, Olga V.; Koch, Rainhard; Yakimov, Michail M.; Bjerga, Gro Elin Kjæreng; Golyshin, Peter N.; Jaeger, Karl-Erich; Ferrer, Manuel CSIC ORCID; INMARE Consortium | artículo |
openAccess | | 13-jun-2022 | Crystal structure of a family VIII β-lactamase fold hydrolase reveals the molecular mechanism for its broad substrate scope | Cea-Rama, Isabel CSIC ORCID; Coscolín, Cristina CSIC ORCID; González-Alfonso, José L.; Raj, Jog; Vasiljević, Marko; Plou Gasca, Francisco José CSIC ORCID ; Ferrer, Manuel CSIC ORCID; Sanz-Aparicio, J. CSIC ORCID | artículo |
openAccess | | 20-jul-2019 | Crystal structure of promiscuous serine ester hydrolases | Cea-Rama, Isabel CSIC ORCID; Coscolín, Cristina CSIC ORCID; Ferrer, Manuel CSIC ORCID; Sanz-Aparicio, J. CSIC ORCID | póster de congreso |
openAccess | | 2021 | Crystal structures of a novel family IV esterase in free and substrate-bound form | Höppner, Astrid; Bollinger, Alexander; Kobus, Stefanie; Thies, Stephan; Coscolín, Cristina CSIC ORCID; Ferrer, Manuel CSIC ORCID; Jaeger, Karl-Erich; Smits, Sander H. J. | artículo |
openAccess | | 28-nov-2017 | Determinants and prediction of esterase substrate promiscuity patterns | Martínez-Martínez, Mónica CSIC ORCID; Coscolín, Cristina CSIC ORCID; Santiago, Gerard; Chow, Jennifer; Stogios, Peter J.; Bargiela, Rafael CSIC ORCID; Gertler, Christoph; Navarro-Fernández, José; Bollinger, Alexander; Thies, Stephan; Méndez-García, Celia; Popovic, Ana; Brown, Greg; Chernikova, Tatyana; García-Moyano, Antonio; Bjerga, Gro Elin Kjæreng; Pérez-García, Pablo CSIC ORCID; Hai, Tran; Pozo, Mercedes V. del; Stokke, Runar; Steen, Ida H.; Cui, Hong; Xu, Xiaohui; Nocek, Boguslaw P.; Alcaide, María CSIC; Distaso, Marco; Mesa, Victoria; Peláez, Ana I.; Sánchez, Jesús; Buchholz, Patrick C. F.; Pleiss, Jürgen; Fernández-Guerra, Antonio; Glöckner, Frank Oliver; Golyshina, Olga V.; Yakimov, Michail M.; Savchenko, Alexei; Jaeger, Karl-Erich; Yakunin, Alexander F.; Streit, Wolfgang R.; Golyshin, Peter N.; Guallar, Victor; Ferrer, Manuel CSIC ORCID; INMARE Consortium | artículo |
openAccess | | 24-feb-2023 | Enzyme adaptation to habitat thermal legacy shapes the thermal plasticity of marine microbiomes | Marasco, Ramona; Fusi, Marco; Coscolín, Cristina CSIC ORCID; Barozzi, Alan; Almendral, David CSIC ORCID; Bargiela, Rafael CSIC ORCID; Gohlke neé Nutschel, Christina; Pfleger, Christopher; Dittrich, Jonas; Gohlke, H.; Matesanz, Ruth CSIC ; Sánchez-Carrillo, Sergio; Mapelli, Francesca; Chernikova, Tatyana; Golyshin, Peter N.; Ferrer, Manuel CSIC ORCID; Daffonchio, Daniele | artículo |
openAccess | | 16-dic-2019 | Genetically engineered proteins with two active sites for enhanced biocatalysis and synergistic chemo- and biocatalysis | Alonso, Sandra; Santiago, Gerard; Cea-Rama, Isabel CSIC ORCID; Fernández-López, Laura; Coscolín, Cristina CSIC ORCID; Modregger, Jan; Ressmann, Anna K.; Martínez-Martínez, Mónica CSIC ORCID; Marrero, Helena; Bargiela, Rafael CSIC ORCID; Pita, Marcos CSIC ORCID ; González-Alfonso, José L.; Briand, Manon L.; Rojo, David; Barbas, Coral; Plou Gasca, Francisco José CSIC ORCID ; Golyshin, Peter N.; Shahgaldian, Patrick; Sanz-Aparicio, J. CSIC ORCID; Guallar, Victor; Ferrer, Manuel CSIC ORCID | artículo |
closedAccess | | 2021 | Promiscuous Esterases Counterintuitively Are Less Flexible than Specific Ones | Nutschel, Christina; Coscolín, Cristina CSIC ORCID; David, Benoit; Mulnaes, David; Ferrer, Manuel CSIC ORCID; Jaeger, Karl-Erich; Gohlke, Holger | artículo |
openAccess | | 18-abr-2021 | Structure and evolutionary trace-assisted screening of a residue swapping the substrate ambiguity and chiral specificity in an esterase | Cea-Rama, Isabel CSIC ORCID; Coscolín, Cristina CSIC ORCID; Katsonis, Panagiotis; Bargiela, Rafael CSIC ORCID; Golyshin, Peter N.; Lichtarge, Olivier; Ferrer, Manuel CSIC ORCID; anz-Aparicio, J. | artículo |
openAccess | | 31-ene-2023 | The Mobility of the Cap Domain Is Essential for the Substrate Promiscuity of a Family IV Esterase from Sorghum Rhizosphere Microbiome | Distaso, Marco; Cea-Rama, Isabel CSIC ORCID; Coscolín, Cristina CSIC ORCID; Chernikova, Tatyana N; Tran, Hai; Ferrer, Manuel CSIC ORCID; Sanz-Aparicio, J. CSIC ORCID; Golyshin, Peter N | artículo |
openAccess | | 1-ago-2023 | Transforming an esterase into an enantioselective catecholase through bioconjugation of a versatile metal-chelating inhibitor | Fernandez-Lopez, Laura; Cea-Rama, Isabel CSIC ORCID; Alvarez-Malmagro, Julia; Ressmann, Anna K.; Gonzalez-Alfonso, Jose L.; Coscolín, Cristina CSIC ORCID; Shahgaldian, Patrick; Plou Gasca, Francisco José CSIC ORCID ; Modregger, Jan; Pita, Marcos CSIC ORCID ; Sanz-Aparicio, J. CSIC ORCID; Ferrer, Manuel CSIC ORCID | artículo |
closedAccess | | 11-dic-2020 | Tuning the Properties of Natural Promiscuous Enzymes by Engineering Their Nano-environment | Giunta, C.I.; Cea-Rama, Isabel CSIC ORCID; Alonso, Sandra; Briand, Manon L.; Bargiela, Rafael CSIC ORCID; Coscolín, Cristina CSIC ORCID; Corvini, P.F.X.; Ferrer, Manuel CSIC ORCID; Sanz-Aparicio, J. CSIC ORCID; Shahgaldian, Patrick | artículo |