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Browsing by Author Balzarini, Jan

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RightsPreviewIssue DateTitleAuthor(s)Type
closedAccess2001Anti-HIV-1 activity of benzothiadiazine dioxideMartinez, Ana; Gil, Carmen; Castro, Ana; Pérez, Concepción; Witvrouw, M.; Pannecouque, C.; Balzarini, Jan; De Clercq, ErikArtículo
closedAccess2015Conservation of antiviral activity and improved selectivity in PMEO-DAPym upon pyrimidine to triazine scaffold hoppingCastro, Sonia de; Fernández-Cureses, Gloria; Andrei, G; Snoeck, R.; Sánchez-Murcia, Pedro A.; Korban, B.; Gago, Federico; Balzarini, Jan; Camarasa Rius, María JoséArtículo
closedAccess2011Crystal structure of tert -butyldimethylsilyl-spiroaminooxathioledioxide- thymine (TSAO-T) in complex with HIV-1 reverse transcriptase (RT) redefines the elastic limits of the non-nucleoside inhibitor-binding pocketDas, Krishna; Bauman, J. D.; Rim, A. S.; Dharia, C.; Clark, A. D.; Camarasa Rius, María José; Balzarini, Jan; Arnold, E.Artículo
closedAccess2015Design, synthesis, and biological evaluation of unconventional aminopyrimidine, aminopurine, and amino-1,3,5-triazine methyloxynucleosidesFernández-Cureses, Gloria; Castro, Sonia de; Jimeno, M. Luisa; Balzarini, Jan; Camarasa Rius, María JoséArtículo
closedAccess2011Dipeptidyl peptidase IV dependent water-soluble prodrugs of highly lipophilic bicyclic nucleoside analoguesDiez-Torrubia, Alberto; Balzarini, Jan; Andrei, G; Snoeck, R.; De Meester, Ingrid; Camarasa Rius, María José; Velázquez, SonsolesArtículo
closedAccess2012Dipeptidyl Peptidase IV-Activated Prodrugs of Anti- Varicella Zoster Virus Bicyclic Nucleoside Analogues Containing Different Self-Cleavage Spacer SystemsDiez-Torrubia, Alberto; Cabrera, Silvia; De Meester, Ingrid; Camarasa Rius, María José; Balzarini, Jan; Velázquez, SonsolesArtículo
closedAccess2015Dipeptidyl-peptidase IV (DPP IV/CD26)-activated prodrugs: A successful strategy for improving water solubility and oral bioavailabilityVelázquez, Sonsoles; Castro, Sonia de; Diez-Torrubia, Alberto; Balzarini, Jan; Camarasa Rius, María JoséArtículo
closedAccess3-Feb-2012Dipeptidyl-peptidase IV (DPPIV/CD26)-based prodrugs of hydroxy-containing drugsDiez-Torrubia, Alberto; Cabrera, Silvia; Lambeir, Anne-Marie; Balzarini, Jan; Camarasa Rius, María José; Velázquez, SonsolesArtículo
closedAccessaccesoRestringido.pdf.jpg2014Discovery and SAR studies of a novel class of cytotoxic 1,4-disubstituted piperidines via Ugi reactionCastro, Sonia de; Camarasa Rius, María José; Balzarini, Jan; Velázquez, SonsolesArtículo
closedAccess2011From β-Amino-γ-sultone to Unusual Bicyclic Pyridine and Pyrazine Heterocyclic Systems: Synthesis and Cytostatic and Antiviral ActivitiesCastro, Sonia de; Familiar, Olga; Andrei, G; Snoeck, R.; Balzarini, Jan; Camarasa Rius, María José; Velázquez, SonsolesArtículo
openAccessWO2011085454A1.pdf.jpg21-Jul-2011gp120 -binding benzene compounds and saccharide compoundsBalzarini, Jan; Carrero, Paula; Casanova, Elena; Pérez Pérez, María Jesús; San-Félix, AnaSolicitud de patente
closedAccess2000HIV-1 specific reverse transcriptase inhibitors: Why are TSAO-nucleosides so unique?Camarasa Rius, María José; San-Felix, Alejandra; Pérez Pérez, María Jesús; Velázquez, Sonsoles; Álvarez, Rosa; Chamorro, Cristina; Jimeno, M. Luisa; Perez, Carlos; Gago, Federico; De Clercq, Erik; Balzarini, JanArtículo
closedAccessaccesoRestringido.pdf.jpg2009Identification of aspartic acid-203 in human thymidine phosphorylase as an important residue for both catalysis and non-competitive inhibition by the small molecule >crystallization chaperone> 5′-O-tritylinosine (KIN59)Bronckaers, A.; Aguado, Leire; Negri, Ana; Camarasa Rius, María José; Balzarini, Jan; Peréz-Pérez, María Jesús; Gago, F.; Liekens, S.Artículo
openAccessWO2009030410A1.pdf.jpg12-Mar-2009Improvements in or relating to compositions for the treatment or prophylaxis of viral infectionsBalzarini, Jan; Camarasa Rius, María José; Velázquez, SonsolesPatente
closedAccess2015Linear and branched alkyl-esters and amides of gallic acid and other (mono-, di- and tri-) hydroxy benzoyl derivatives as promising anti-HCV inhibitorsRivero-Buceta, Eva; Carrero, P.; Doyagüez, Elisa G.; Madrona, Andrés; Quesada, Ernesto; Camarasa Rius, María José; Peréz-Pérez, María Jesús; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Félix, AnaArtículo
openAccessGigante_full_article.pdf.jpg2014Microwave-assisted synthesis of C-8 aryl and heteroaryl inosines and determination of their inhibitory activities against Plasmodium falciparum purine nucleoside phosphorylaseGigante, Alba; Priego, Eva María; Sánchez-Carrasco, Paula; Ruiz-Pérez, Luis Miguel; Vande Voorde, Johan; Camarasa Rius, María José; Balzarini, Jan; González-Pacanowska, D.; Pérez Pérez, María JesúsArtículo
openAccessOrg. Biomol. Chem., 2014.pdf.jpg2014Multivalent agents containing 1-substituted 2,3,4-trihydroxyphenyl moieties as novel synthetic polyphenols directed against HIV-1Flores, Aida; Camarasa Rius, María José; Pérez Pérez, María Jesús; San-Félix, Ana; Balzarini, Jan; Quesada, ErnestoArtículo
openAccessWO2015051422_A1.pdf.jpg16-Apr-2015New pradimicin derivatives for the treatment of diseases caused by kinetoplastidsBalzarini, Jan; González-Pacanowska, D.; Ruiz-Pérez, Luis Miguel; Castillo Acosta, Víctor; Agarashi, YasuhiroSolicitud de patente
closedAccessaccesoRestringido.pdf.jpg2000Nonnucleoside human cytomegalovirus inhibitors: Synthesis and antiviral evaluation of (chlorophenylmethyl)benzothiadiazine dioxide derivativesMartinez, Ana; Gil, Carmen; Pérez, Concepción; Castro, Ana; Prieto, Columbiana; Otero, Joaquín; Andrei, G; Snoeck, R.; Balzarini, Jan; De Clercq, ErikArtículo
closedAccess1997Novel analogues of the anti HIV-1 agent TSAO-T modified at the 3'-spiro moietyÁlvarez, Rosa; Jimeno, M. Luisa; De Clercq, Erik; Balzarini, Jan; Camarasa Rius, María JoséArtículo