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DerechosPreviewFecha Public.TítuloAutor(es)Tipo
closedAccessaccesoRestringido.pdf.jpg27-ago-2020Shared D-J rearrangements reveal cell of origin of TCF3-ZNF384 and PTPN11 mutations in monozygotic twins with concordant BCP-ALLBueno, Clara; Ballerini, Paola; Varela, Ignacio CSIC ORCID; Menéndez, Pablo; Bashford-Rogers, Rachaelartículo
openAccesssharecarci.pdf.jpg2017Shared oncogenic pathways implicated in both virus-positive and UV-induced merkel cell carcinomasGonzález-Vela, María del Carmen; Curiel-Olmo, Soraya; Agraz-Doblas, Antonio; Varela, Ignacio CSIC ORCID; Piris, Miguel A.; Vaqué, José P. CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2014Sin3b Interacts with Myc and decreases Myc levelsGarcía-Sanz, Pablo CSIC; Quintanilla, Andrea CSIC; Lafita, M. Carmen CSIC ORCID; Moreno-Bueno, Gema CSIC ORCID; García-Gutiérrez, Lucía CSIC ORCID; Varela, Ignacio CSIC ORCID; García del Portillo, Francisco CSIC ORCID ; León, Javier CSIC ORCID CVNartículo
openAccessSomatic_Osotio_PV_Art2018.pdf.jpg27-nov-2018Somatic Mutations Reveal Lineage Relationships and Age-Related Mutagenesis in Human HematopoiesisOsorio, Fernando G.; Huber, Axel Rosendahl; Oka, Rurika; Verheul, Mark; Patel, Sachin H.; Hasaart, Karlijn; Fonteijne, Lisanne de la; Varela, Ignacio CSIC ORCID; Camargo, Fernando D.; Boxtel, Ruben vanartículo
openAccessSomatic SF3B1.pdf.jpg2011Somatic SF3B1 mutation in myelodysplasia with ring sideroblastsVarela, Ignacio CSIC ORCIDartículo
openAccesslung cancer evolution.pdf.jpg2014Spatial and temporal diversity in genomic instability processes defines lung cancer evolutionBruin, Elza C. de; Gerlinger, Marco; Varela, Ignacio CSIC ORCID; Swanton, Charlesartículo
closedAccessaccesoRestringido.pdf.jpg2011Splicing-directed therapy in a new mouse model of human accelerated agingVarela, Ignacio CSIC ORCIDartículo
openAccessAAT-Nature-revision-final.pdf.jpg2011Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cellsVarela, Ignacio CSIC ORCID; Bradley, Allan; Vallier, Ludovicartículo
closedAccessaccesoRestringido.pdf.jpg2015The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membraneLoregger, Anke; Varela, Ignacio CSIC ORCID; Gerhard, Markusartículo
openAccessThe HDAC7–TET2 epigenetic axis_Azagra_PV_Art2022.pdf.jpg26-ago-2022The HDAC7-TET2 epigenetic axis is essential during early B lymphocyte developmentAzagra, Alba; Meler, Ainara; Barrios, Oriol de; Tomás-Daza, Laureano; Collazo, Olga; Monterde, Beatriz CSIC ORCID; Obiols, Mireia; Rovirosa, Llorenç; Vila-Casadesús, Maria; Cabrera-Pasadas, Mónica; Gusi-Vives, Mar; Graf, Thomas; Varela, Ignacio CSIC ORCID; Sardina, José Luis; Javierre, Biola M.; Parra, Maribelartículo
closedAccessaccesoRestringido.pdf.jpg14-feb-2020The MNT transcription factor autoregulates its expression and supports proliferation in MYC-associated factor X (MAX)-deficient cellsLafita, M. Carmen CSIC ORCID; Liaño-Pons, Judith CSIC ORCID; Quintanilla, Andrea CSIC; Varela, Ignacio CSIC ORCID; Blanco, Rosa CSIC; Ourique, Fabiana; Bretones, Gabriel CSIC ORCID; Aresti, Julia; Molina Hoyo, Ester CSIC ORCID; Carroll, Patrick; Hurlin, Peter; Romero, Octavio A.; Sanchez-Céspedes, Montse; Eisenman, Robert N.; Delgado, M. Dolores CSIC ORCIDartículo
openAccessMYC_antagonis_Lafita_ComCong2018.pdf.jpg3-jul-2018The MYC antagonist MNT beyond MAX interactionLafita, M. Carmen CSIC ORCID; Liaño-Pons, Judith CSIC ORCID; Varela, Ignacio CSIC ORCID; Blanco, Rosa CSIC; Aresti, Julia; Carroll, Patrick; Hurlin, Peter; Eisenman, Robert N.; Delgado, M. Dolores CSIC ORCID; León, Javier CSIC ORCID CVNpóster de congreso
openAccessTumor_Gonzalez_Art2020.pdf.jpgene-2020Tumor Functional Heterogeneity Unraveled by scRNA-seq TechnologiesGonzález-Silva, Laura CSIC ORCID; Quevedo, Laura CSIC ORCID; Varela, Ignacio CSIC ORCIDartículo
openAccessUnraveling_Agraz_Doblas_Art2019.pdf.jpg2019Unraveling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysisAgraz-Doblas, Antonio; Bueno, Clara; Bashford-Rogers, Rachael; Roy, Anindita; Schneider, Pauline; Bardini, Michela; Ballerini, Paola; Cazzaniga, Gianni; Moreno, Thaidy CSIC; Revilla, Carlos CSIC; Gut, Marta; Valsecchi, Maria G.; Roberts, Irene; Pieters, Rob; Lorenzo, Paola De; Varela, Ignacio CSIC ORCID; Menéndez, Pablo; Stam, Ronald W.artículo
closedAccessaccesoRestringido.pdf.jpgjun-2018UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programsGozdecka, Malgorzata; Meduri, Eshwar; Mazan, Milena; Tzelepis, Konstantinos; Dudek, Monika; Knights, Andrew J.; Pardo, Mercedes; Yu, Lu; Choudhary, Jyoti S.; Metzakopian, Emmanouil; Iyer, Vivek; Yun, Haiyang; Park, Naomi; Varela, Ignacio CSIC ORCID; Bautista, Rubén; Collord, Grace; Dovey, Oliver M.; Garyfallos, Dimitrios A.; Braekeleer, Etienne De; Kondo, Saki; Cooper, Jonathan; Göttgens, Berthold; Bullinger, Lars; Northcott, Paul A.; Adams, David; Vassiliou, George S.; Huntly, Brian J. P.artículo
closedAccessaccesoRestringido.pdf.jpg2014Whole-exome sequencing in splenic marginal zone lymphoma reveals mutations in genes involved in marginal zone differentiationVaqué, José P. CSIC ORCID; Varela, Ignacio CSIC ORCID; Piris, Miguel A.artículo