Mostrando resultados 6 a 20 de 20
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| Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
| openAccess |  | 2018 | High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design | Bueno, Oskia CSIC; Estévez-Gallego, Juan CSIC ORCID ; Martins, S.; Prota, Andrea E.; Gago, Federico CSIC ORCID; Gómez-SanJuan, Asier CSIC; Camarasa Rius, María José CSIC ORCID; Barasoain, Isabel CSIC ; Steinmetz, Michel O.; Díaz, José Fernando CSIC ORCID ; Peréz-Pérez, María-Jesús CSIC ORCID ; Liekens, Sandra; Priego, Eva María CSIC ORCID | artículo |
| closedAccess |  | 1-feb-2013 | Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents | Prota, Andrea E.; Bargsten, Katja; Zurwerra, Didier; Field, Jessica J.; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinz; Steinmetz, Michel O. | artículo |
| openAccess |  | 31-jul-2016 | Pironetin binds covalently to Cys316 and perturbs a major loop and helix of -tubulin to inhibit microtubule formation | Prota, Andrea E.; Setter, J.; Waight, Andrew B.; Bargsten, Katja; Murga, Juan; Díaz, José Fernando CSIC ORCID ; Steinmetz, Michel O. | artículo |
| openAccess |  | 23-ene-2018 | Protein-ligand complex for structure-based design: impact on the affinity and antitumor activity of new tubulin ligands | Bueno, Oskia CSIC; Estévez-Gallego, Juan CSIC ORCID ; Martins, S.; Prota, Andrea E.; Gago, Federico CSIC ORCID; Gómez-SanJuan, Asier CSIC; Camarasa Rius, María José CSIC ORCID; Barasoain, Isabel CSIC ; Steinmetz, Michel O.; Díaz, José Fernando CSIC ORCID ; Liekens, Sandra; Peréz-Pérez, María-Jesús CSIC ORCID ; Priego, Eva María CSIC ORCID | comunicación de congreso |
| openAccess |  | 22-jun-2017 | Quinolin-6-yloxyacetamides are microtubule destabilizing agents that bind to the colchicine site of tubulin | Sharma, Ashwani; Sáez-Calvo, Gonzalo CSIC; Olieric, Natacha; Balaguer, Francisco de Asís CSIC ORCID; Barasoain, Isabel CSIC ; Lamberth, Clemens; Díaz, José Fernando CSIC ORCID ; Steinmetz, Michel O. | artículo |
| closedAccess |  | 2012 | Sequence determinants of a microtubule tip localization signal (MtLS) | Martínez Buey, Rubén CSIC ORCID; Pereda, José M. de CSIC ORCID ; Steinmetz, Michel O. | artículo |
| openAccess |  | 22-nov-2019 | Structural basis of colchicine-site targeting acylhydrazones active against multidrug-resistant acute lymphoblastic leukemia | Cury, Nathália Moreno; Mühlethaler, Tobias; Laranjeira, Angelo Brunelli Albertoni; Canevarolo, Rafael Renatino; Zenatti, Priscila Pini; Lucena-Agell, Daniel CSIC ORCID ; Barasoain, Isabel CSIC ; Song, Chunhua; Sun,Dongxiao; Dovat, Sinisa; Yunes, Rosendo Augusto; Prota, Andrea E.; Steinmetz, Michel O.; Díaz, José Fernando CSIC ORCID ; Yunes, José Andrés | artículo |
| openAccess |  | 16-feb-2017 | Structural basis of microtubule stabilization by discodermolide | Prota, Andrea E.; Bargsten, Katja; Redondo-Horcajo, Mariano CSIC ORCID ; Smith III, Amos B.; Yang, Chia-Ping H.; McDaid, Hayley M.; Paterson, Ian; Horwitz, Susan; Díaz, José Fernando CSIC ORCID ; Steinmetz, Michel O. | artículo |
| openAccess |  | 13-jul-2020 | Structural basis of noscapine activation for tubulin binding | Oliva, María A. CSIC ORCID ; Prota, Andrea E.; Rodríguez-Salarichs, Javier CSIC; Wenxin, Gu; Bennani, Y. L.; Jiménez-Barbero, Jesús CSIC ORCID; Bargsten, Katja; Canales, Ángeles CSIC ORCID; Steinmetz, Michel O.; Díaz, José Fernando CSIC ORCID | artículo |
| openAccess |  | 13-dic-2016 | Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells | Trigili, Chiara CSIC; Barasoain, Isabel CSIC ; Sánchez-Murcia, Pedro A. CSIC ORCID; Bargsten, Katja; Redondo-Horcajo, Mariano CSIC ORCID ; Nogales, Aurora CSIC ORCID; Gardner, Nicola M.; Meyer, Arndt; Naylor, Guy J.; Gomez-Rubio, Elena CSIC ORCID; Gago, Federico CSIC ORCID; Steinmetz, Michel O.; Paterson, Ian; Prota, Andrea E.; Díaz, José Fernando CSIC ORCID | artículo |
| openAccess |  | 6-mar-2023 | Structural insight into the stabilization of microtubules by taxanes | Prota, Andrea E.; Lucena-Agell, Daniel CSIC ORCID ; Ma, Yuntao; Estévez-Gallego, Juan CSIC ORCID ; Li, Shuo; Bargsten, Katja; Josa-Prado, Fernando CSIC ORCID; Altmann, Karl-Heinz; Gaillard, Natacha; Kamimura, Shinji; Mühlethaler, Tobias; Gago, Federico CSIC ORCID; Oliva, María A. CSIC ORCID ; Steinmetz, Michel O.; Fang, Wei-Shuo; Díaz, José Fernando CSIC ORCID | artículo |
| openAccess |  | 10-mar-2020 | Structural model for differential cap maturation at growing microtubule ends | Estévez-Gallego, Juan CSIC ORCID ; Josa-Prado, Fernando CSIC ORCID; Ku, Siou; Martínez Buey, Rubén CSIC ORCID; Balaguer, Francisco de Asís CSIC ORCID; Prota, Andrea E.; Lucena-Agell, Daniel CSIC ORCID ; Kamma-Lorger, C.S.; Yagi, Toshiki; Iwamoto, Hiroyuki; Duchesne, Laurence; Barasoain, Isabel CSIC ; Steinmetz, Michel O.; Chrétien, Denis; Kamimura, Shinji; Díaz, José Fernando CSIC ORCID ; Oliva, María A. CSIC ORCID | artículo |
| openAccess | | 14-nov-2019 | Structure, Thermodynamics, and Kinetics of Plinabulin Binding to Two Tubulin Isotypes | La Sala, Giuseppina; Olieric, Natacha; Sharma, Ashwani; Viti, Federica; Balaguer, Francisco de Asís CSIC ORCID; Huang, Lan; Tonra, James R.; Lloyd, George Kenneth; Decherchi, Sergio; Díaz, José Fernando CSIC ORCID ; Steinmetz, Michel O.; Cavalli, Andrea | artículo |
| closedAccess |  | 15-ene-2019 | Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents | Brindisi, Margherita; Ulivieri, Cristina; Alfano, Gloria; Gemma, Sandra; Balaguer, Francisco de Asís CSIC ORCID; Khan, Tuhina; Grillo, Alessandro; Chemi, Giulia; Menchon, Grégory; Prota, Andrea E.; Olieric, Natacha; Lucena-Agell, Daniel CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Nebbioso, Angela; Conte, Mariarosaria; Lopresti, Ludovica; Magnano, Stefania; Amet, Rebecca; Kinsella, Paula; Zisterer, Daniela M.; Ibrahim, Ola; O'Sullivan, Jeff; Morbidelli, Lucia; Spaccapelo, Roberta; Baldari, Cosima T.; Butini, Stefania; Novellino, Ettore; Campiani, Giuseppe; Altucci, Lucia; Steinmetz, Michel O.; Brogi, Simone | artículo |
| closedAccess |  | mar-2020 | Taxanes convert regions of perturbed microtubule growth into rescue sites | Rai, Ankit; Liu, Tianyang; Glauser, Simon; Katrukha, Eugene A.; Estévez-Gallego, Juan CSIC ORCID ; Rodríguez-García, Ruddi; Fang, Wei-Shuo; Díaz, José Fernando CSIC ORCID ; Steinmetz, Michel O.; Altmann, Karl-Heinz; Kapitein, Lukas C.; Moores, Carolyn A.; Akhmanova, Anna | artículo |
