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Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
openAccess | | 1-jun-2011 | Compuestos derivados de 1,8-naftiridinas y su uso en el tratamiento de enfermedades neurodegenerativas | Romero Martínez, Alejandro; García García, Antonio; García López, Manuela; Egea, Javier; Chioua, Mourad CSIC ORCID ; Villarroya Sánchez, Mercedes; Soriano, Elena CSIC; León, Rafael CSIC ORCID ; Marco-Contelles, José CSIC ORCID; Ríos Salgado, Cristóbal; Samadi, Abdelouahid CSIC ORCID | solicitud de patente |
closedAccess | | 2015 | D - And L -Mannose-Containing glyco-Oligoamides Show Distinct Recognition Properties When Interacting with DNA | Blázquez-Sánchez, M. Teresa CSIC; Marcelo, Filipa CSIC ORCID; Fernández-Alonso, M. Carmen CSIC ; Villar-Guerra, Rafael del; Samadi, Abdelouahid CSIC ORCID; Cañada, F. Javier ; Jiménez-Barbero, Jesús CSIC ORCID; Vicent, Cristina CSIC ORCID | artículo |
openAccess | | 27-sep-2011 | Derivados de 2-amino-3,5-dicianopiridina y 2-cloro-3,5-dicianopiridina como inhibidores de las enzinas colinesterasas y con capacidad neuroprotectora | Samadi, Abdelouahid CSIC ORCID; Álvarez-Pérez, Mónica CSIC ORCID; Soriano, Elena CSIC; Valderas, Carolina CSIC; García García, Antonio | solicitud de patente |
closedAccess | | 2014 | Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil-indolyl hybrids as multipotent cholinesterase/monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease | Bautista-Aguilera, Óscar M. CSIC ORCID; Esteban, Gerard; Bolea, Irene; Nikolic, Katarina; Agbaba, Danica; Moraleda, Ignacio; Iriepa, Isabel; Samadi, Abdelouahid CSIC ORCID; Soriano, Elena CSIC; Unzeta, Mercedes; Marco-Contelles, José CSIC ORCID | artículo |
closedAccess | | 2014 | Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease | Wang, L.; Esteban, Gerard; Ojima, Masaki; Bautista-Aguilera, Óscar M. CSIC ORCID; Inokuchi, Tsutomu; Moraleda, Ignacio; Iriepa, Isabel; Samadi, Abdelouahid CSIC ORCID; Youdim, Moussa B. H.; Romero Jódar, Alejandro CSIC ORCID; Soriano, Elena CSIC; Herrero-Labrador, Raquel CSIC ORCID; Fernández Fernández, Ana Patricia CSIC; Martínez-Murillo, Ricardo CSIC ORCID; Marco-Contelles, José CSIC ORCID; Unzeta, Mercedes | artículo |
closedAccess | | 2014 | Effects of novel monoamine oxidases and cholinesterases targeting compounds on brain neurotransmitters and behavior in rat model of vascular dementia | Stasiak, Anna; Mussur, Miroslaw; Unzeta, Mercedes; Samadi, Abdelouahid CSIC ORCID; Marco-Contelles, José CSIC ORCID; Fogel, W. Agnieszka | artículo |
closedAccess | | 2013 | Enantioselective neuroprotective effects of tacripyrine ITH122 against oxygen and glucose deprivation in rat hippocampal slices | Romero Jódar, Alejandro CSIC ORCID; Gómez-Rangel, Vanessa; Egea, Javier; Samadi, Abdelouahid CSIC ORCID; Marco-Contelles, José CSIC ORCID; López, Manuela G. | artículo |
openAccess | | 2018 | Identification of a Tool Compound to Study the Mechanisms of Functional Selectivity between D2 and D3 Dopamine Receptors | Reyes-Resina, I.; Samadi, Abdelouahid CSIC ORCID; Navarro, Gemma; Saadeh, H. A.; Khasawneh, M. A.; Mestres, Jordi; Marco-Contelles, José CSIC ORCID; Franco, Rafael | artículo |
closedAccess | | 2015 | α-aryl-N-alkyl nitrones, as potential agents for stroke treatment: Synthesis, theoretical calculations, antioxidant, anti-inflammatory, neuroprotective, and brain-blood barrier permeability properties | Chioua, Mourad CSIC ORCID ; Sucunza, D.; Soriano, Elena CSIC; Hadjipavlou-Litina, Dimitra; Alcázar González, Alberto; Ayuso, I.; Oset-Gasque, María Jesús; Gonzalez, M. P.; Monjas, Leticia CSIC ORCID; Rodríguez-Franco, María Isabel CSIC ORCID ; Marco-Contelles, José CSIC ORCID; Marco-Contelles, José CSIC ORCID; Samadi, Abdelouahid CSIC ORCID | artículo |
closedAccess | | 2014 | Kinetic and structural analysis of the irreversible inhibition of human monoamine oxidases by ASS234, a multi-target compound designed for use in Alzheimer's disease | Esteban, Gerard; Allan, Jennifer; Samadi, Abdelouahid CSIC ORCID; Mattevi, Andrea; Unzeta, Mercedes; Marco-Contelles, José CSIC ORCID; Binda, Claudia; Ramsay, Rona R. | artículo |
openAccess | | 2014 | Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer’s disease: Design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids | Bautista-Aguilera, Óscar M. CSIC ORCID; Esteban, Gerard; Chioua, Mourad CSIC ORCID ; Nikolic, Katarina; Agbaba, Danica; Moraleda, Ignacio; Iriepa, Isabel; Soriano, Elena CSIC; Samadi, Abdelouahid CSIC ORCID; Unzeta, Mercedes; Marco-Contelles, José CSIC ORCID | artículo |
closedAccess | | 2013 | Multipotent, permeable drug ASS234 inhibits Aβ aggregation, possesses antioxidant properties and protects from Aβ-induced apoptosis in vitro | Bolea, Irene; Gella, Alejandro; Monjas, Leticia CSIC ORCID; Pérez, Concepción CSIC ORCID; Rodríguez-Franco, María Isabel CSIC ORCID ; Marco-Contelles, José CSIC ORCID; Samadi, Abdelouahid CSIC ORCID; Unzeta, Mercedes | artículo |
closedAccess | | 2016 | N-Benzylpiperidine derivatives as α7 nicotinic receptor antagonists | Criado, Manuel CSIC ORCID; Mulet, José CSIC ORCID; Sala, Francisco CSIC ORCID; Sala, Salvador CSIC ORCID; Colmena, Inés CSIC; Gandía, Luis; Bautista-Aguilera, Oscar M.; Samadi, Abdelouahid CSIC ORCID; Chioua, Mourad CSIC ORCID ; Marco-Contelles, José CSIC ORCID | artículo |
closedAccess | | 2014 | N-methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a new cholinesterase and monoamine oxidase dual inhibitor | Bautista-Aguilera, Óscar M. CSIC ORCID; Samadi, Abdelouahid CSIC ORCID; Chioua, Mourad CSIC ORCID ; Nikolic, K.; Filipic, S.; Agbaba, Danica; Soriano, Elena CSIC; Andrés, Lucía de CSIC; Rodríguez-Franco, María Isabel CSIC ORCID ; Alcaro, S.; Ramsay, R. R.; Ortuso, F.; Yáñez, Matilde; Marco-Contelles, José CSIC ORCID | artículo |
openAccess | | 22-ago-2011 | New derivatives of propargylamine having neuroprotective capacity for the treatment of alzheimer's and parkinson's diseases | Samadi, Abdelouahid CSIC ORCID; Marco-Contelles, José CSIC ORCID; Bolea Tomás, Irene; Luque, Francisco J.; Unzeta López, Mercedes | solicitud de patente |
closedAccess | | 2013 | Nontoxic and neuroprotective β-naphthotacrines for alzheimer's disease | Esquivias-Pérez, Mario; Maalej, Enma; Romero Jódar, Alejandro CSIC ORCID; Chabchoub, Fakher; Samadi, Abdelouahid CSIC ORCID; Marco-Contelles, José CSIC ORCID; Oset-Gasque, María Jesús | artículo |
closedAccess | | 2013 | Novel tacrine-related drugs as potential candidates for the treatment of Alzheimer's disease | Romero Jódar, Alejandro CSIC ORCID; Cacabelos, Ramón; Oset-Gasque, María Jesús; Samadi, Abdelouahid CSIC ORCID; Marco-Contelles, José CSIC ORCID | artículo |
openAccess | | 18-ene-2012 | Nuevas 2,2'-azopiridinas a partir de 2-aminopiridinas de interés farmacéutico e industrial | Samadi, Abdelouahid CSIC ORCID; Marco-Contelles, José CSIC ORCID; Botelho da Silva, Daniel | solicitud de patente |
openAccess | | 29-sep-2011 | Nuevos derivados de propargilamina con capacidad neuroprotectora para el tratamiento de las enfermedades de Alzheimer y Parkinson | Samadi, Abdelouahid CSIC ORCID; Marco-Contelles, José CSIC ORCID; Bolea Tomás, Irene; Luque, Francisco J.; Unzeta, Mercedes | solicitud de patente |
closedAccess | | 2013 | PP2A ligand ITH12246 protects against memory impairment and focal cerebral ischemia in mice | Lorrio, Silvia; Romero Jódar, Alejandro CSIC ORCID; González-Lafuente, Laura; Lajarín-Cuesta, Rocío; Martínez-Sanz, Francisco J.; Estrada, Martín CSIC ORCID CVN; Samadi, Abdelouahid CSIC ORCID; Marco-Contelles, José CSIC ORCID; Rodríguez-Franco, María Isabel CSIC ORCID ; Villarroya, Mercedes; López, Manuela G.; Ríos, Cristobal de los | artículo |