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closedAccessaccesoRestringido.pdf.jpg22-oct-2012A rationally designed six-residue swap generates comparability in the aggregation behavior of α-synuclein and β-synucleinRoodveldt, Cintia CSIC ORCID; Labrador-Garrido, Adahir CSIC ORCID; Dobson, Christopher M.; Vendruscolo, Micheleartículo
openAccess22879.pdf.jpg2011Alpha-synuclein and the immune response in Parkinson's diseaseRoodveldt, Cintia CSIC ORCID; Labrador-Garrido, Adahir CSIC ORCID; Izquierdo, Guillermo; Pozo, David CSIC ORCIDcapítulo de libro
closedAccessaccesoRestringido.pdf.jpg2016Chaperome screening leads to identification of Grp94/Gp96 and FKBP4/52 as modulators of the α-synuclein-elicited immune responseLabrador-Garrido, Adahir CSIC ORCID; Cejudo-Guillén, Marta CSIC ORCID; Leal-Lasarte, María M. CSIC ORCID; Klippstein, Rebecca CSIC; Villadiego, Javier CSIC ORCID; Toledo-Aral, Juan José CSIC ORCID; Dobson, Christopher M.; Pozo, David CSIC ORCID; Roodveldt, Cintia CSIC ORCIDartículo
closedAccess2009Chaperone proteostasis in Parkinson's disease: stabilization of the Hsp70/α-synuclein complex by HipRoodveldt, Cintia CSIC ORCID; Fernández Montesinos, Rafael CSIC; Pozo, David CSIC ORCID; Dobson, Christopher M.artículo
openAccessImmunity Inflam   Disease - 2015 - Labrador‐Garrido - Chaperoned amyloid proteins for immune manipulation   ‐Synuclein.pdf.jpgdic-2014Chaperoned amyloid proteins for immune manipulation: A-synuclein/hsp70 shifts immunity toward a modulatory phenotypeLabrador-Garrido, Adahir CSIC ORCID; Cejudo-Guillén, Marta CSIC ORCID; Klippstein, Rebecca CSIC; De Genst, Erwin J.; Tomás-Gallardo, Laura CSIC ORCID ; Leal-Lasarte, María M. CSIC ORCID; Villadiego, Javier CSIC ORCID; Toledo-Aral, Juan José CSIC ORCID; Dobson, Christopher M.; Pozo, David CSIC ORCID; Roodveldt, Cintia CSIC ORCIDartículo
openAccessImmunochemical Markers of the Amyloid Cascade.pdf.jpg20-mar-2017Commentary: Immunochemical Markers of the Amyloid Cascade in the Hippocampus in Motor Neuron DiseasesJohnson, Ian Paul; Roodveldt, Cintia CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg17-jul-2019Differential Interactome and Innate Immune Response Activation of Two Structurally Distinct Misfolded Protein OligomersMannini, Benedetta; Vecchi, Giulia; Labrador-Garrido, Adahir CSIC ORCID; Fabre, Bertrand; Fani, Giulia; Franco, Jaime M. CSIC ORCID; Lilley, Kathryn; Pozo, David CSIC ORCID; Vendruscolo, Michele; Chiti, Fabrizio; Dobson, Christopher M.; Roodveldt, Cintia CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpgoct-2021Distinct responses of human peripheral blood cells to different misfolded protein oligomersLeal-Lasarte, María M. CSIC ORCID; Mannini, Benedetta; Chiti, Fabrizio; Vendruscolo, Michele; Dobson, Christopher M.; Roodveldt, Cintia CSIC ORCID; Pozo, David CSIC ORCIDartículo
openAccesseditorialchaperones.pdf.jpg2017Editorial: Molecular chaperones and neurodegenerationRoodveldt, Cintia CSIC ORCID; Outeiro, Tiago F.; Braun, Félixartículo
openAccessjournal.pone.0013481[1].pdf.jpgoct-2010Glial Innate Immunity Generated by Non-Aggregated Alpha-Synuclein in Mouse: Differences between Wild-type and Parkinson's Disease-Linked MutantsRoodveldt, Cintia CSIC ORCID; Labrador-Garrido, Adahir CSIC ORCID; González-Rey, Elena CSIC ORCID; Fernández Montesinos, Rafael CSIC; Caro, M.; Lachaud, Christian C. CSIC ORCID CVN; Waudby, Christopher A.; Delgado, Mario; Dobson, Christopher M.; Pozo, David CSIC ORCIDartículo
openAccessHsp70_Oligomerization_Aprile.pdf.jpg28-jun-2013Hsp70 Oligomerization Is Mediated by an Interaction between the Interdomain Linker and the Substrate-Binding DomainAprile, Francesco A.; Dhulesia, Anne; Stengel, Florian; Roodveldt, Cintia CSIC ORCID; Benesch, Justin L.P.; Tortora, Paolo; Robinson, Carol V.; Salvatella, Xavier; Dobson, Christopher M.; Cremades, Nuniloartículo
openAccessijms-22-13280.pdf.jpg10-dic-2021Immune signaling kinases in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)García-García, Raquel CSIC ORCID; Martín-Herrero, Laura; Blanca-Pariente, Laura; Pérez-Cabello, Jesús Ángel; Roodveldt, Cintia CSIC ORCIDartículo de revisión
closedAccessaccesoRestringido.pdf.jpg2018Immunization with α-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic Parkinsonism modelVilladiego, Javier CSIC ORCID; Labrador-Garrido, Adahir CSIC ORCID; Franco, Jaime M. CSIC ORCID; Leal-Lasarte, María M. CSIC ORCID; De Genst, Erwin J.; Dobson, Christopher M.; Pozo, David CSIC ORCID; Toledo-Aral, Juan José CSIC ORCID; Roodveldt, Cintia CSIC ORCIDartículo
openAccesspérez-cabello-et-al-2023-mapk-mak-mrk-overlapping-kinase-(mok)-controls-microglial-inflammatory-type-i-ifn-responses.pdf.jpg3-jul-2023MAPK/MAK/MRK overlapping kinase (MOK) controls microglial inflammatory/type-I IFN responses via Brd4 and is involved in ALSPérez-Cabello, Jesús Ángel; Silvera-Carrasco, Lucía; Franco, Jaime M. CSIC ORCID; Capilla-González, Vivian CSIC ORCID; Armaos, Alexandros; Gómez-Lima, María; García-García, Raquel CSIC ORCID; Yap, Xin Wen; Leal-Lasarte, Magdalena; Lall, Deepti; Baloh, Robert H.; Martínez, Salvador CSIC ORCID; Miyata, Yoshihiko; Tartaglia, Gian G.; Sawarkar, Ritwick; García-Domínguez, Mario CSIC ORCID; Pozo, David CSIC ORCID; Roodveldt, Cintia CSIC ORCIDartículo
openAccessprotein oligomers.pdf.jpg16-jul-2012Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomersMannini, Benedetta; Roodveldt, Cintia CSIC ORCID; Chiti, Fabrizioartículo
openAccessPreconditioning_Microglia_ Roodveldt.pdf.jpg13-nov-2013Preconditioning of microglia by α-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulationRoodveldt, Cintia CSIC ORCID; Labrador-Garrido, Adahir CSIC ORCID; Lachaud, Christian C. CSIC ORCID CVN; Fernández Montesinos, Rafael CSIC; Benítez-Rondán, Alicia CSIC; Hmadcha, Abdelkrim CSIC ORCID; Pozo, David CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2016The 'Omics' of Amyotrophic Lateral SclerosisCaballero-Hernández, Diana CSIC ORCID; Toscano, Miguel G. CSIC ORCID; Cejudo-Guillén, Marta CSIC ORCID; García-Martín, María L. CSIC ORCID; López-Enríquez, Soledad CSIC ORCID; Franco, Jaime M. CSIC ORCID; Quintana, Francisco J.; Roodveldt, Cintia CSIC ORCID; Pozo, David CSIC ORCIDartículo
openAccesscahperoninter.pdf.jpg2017The chaperonin CCT inhibits assembly of α-synuclein amyloid fibrils by a specific, conformation-dependent interactionSot, Begoña CSIC ORCID; Rubio-Muñoz, Alejandra; Leal-Quintero, Ahudrey; Martínez-Sabando, Javier CSIC; Marcilla, Miguel CSIC ORCID; Roodveldt, Cintia CSIC ORCID; Valpuesta, José M. CSIC ORCID artículo