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DerechosPreviewFecha Public.TítuloAutor(es)Tipo
openAccessEfficacy decrease_García_Crespo_PV_Art2022.pdf.jpg2022Efficacy decrease of antiviral agents when administered to ongoing hepatitis C virus infections in cell cultureGarcía-Crespo, Carlos; Vázquez-Sirvent, Lucía; Somovilla, Pilar; Soria, María Eugenia; Gallego, Isabel CSIC ORCID; Ávila, Ana Isabel de; Martínez-González, Brenda; Durán-Pastor, Antoni; Domingo, Esteban CSIC ORCID; Perales, Celia CSIC ORCIDartículo
openAccessJBerenguer_NAR_6473.pdf.jpg2003Enhancement of DNA, cDNA synthesis and fidelity at high temperatures by a dimeric single-stranded DNA-binding proteinPerales, Celia CSIC ORCID; Cava, Felipe CSIC ORCID; Meijer, Wilfried J. J. CSIC ORCID; Berenguer, José CSIC ORCIDartículo
openAccessPeralesC_ExploratioofSequenceSpace.pdf.jpg31-mar-2014Exploration of sequence space as the basis of viral RNA genome segmentationMoreno, Elena CSIC; Ojosnegros Martos, Samuel; García-Arriaza, Juan CSIC ORCID ; Escarmís, Cristina ; Domingo, Esteban CSIC ORCID; Perales, Celia CSIC ORCIDartículo
openAccessE_Domingo_Plos_One.pdf.jpg2013Extinction of Hepatitis C Virus by Ribavirin in Hepatoma Cells Involves Lethal MutagenesisOrtega-Prieto, Ana M. CSIC ORCID; Sheldon, Julie CSIC ORCID; Grande-Pérez, Ana CSIC ORCID ; Tejero, Héctor; Gregori, Josep Maria; Quer, Josep; Esteban, Juan Ignacio; Esteban, Domingo; Perales, Celia CSIC ORCIDartículo
openAccessaac.00394-23.pdf.jpg27-jun-2023Fitness-Dependent, Mild Mutagenic Activity of Sofosbuvir for Hepatitis C VirusMartínez-González, Brenda; Gallego, Isabel CSIC ORCID; Gregori, Josep; Soria, María Eugenia; Somovilla, Pilar; de Ávila, Ana Isabel; García-Crespo, Carlos; Durán-Pastor, Antoni; Briones, Carlos CSIC ORCID; Gómez, Jordi; Quer, Josep; Domingo, Esteban CSIC ORCID; Perales, Celia CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2012From quasispecies theory to viral quasispecies: How complexity has permeated virologyDomingo, Esteban CSIC ORCID; Perales, Celia CSIC ORCIDartículo
openAccessaccesoRestringido.pdf.jpg24-feb-2020Guanosine inhibits hepatitis C virus replication and increases indel frequencies, associated with altered intracellular nucleotide poolsSabariegos Jareño, Mª del Rosario; Ortega-Prieto, Ana M. CSIC ORCID; Díaz Martinez, Luis; Grande-Pérez, Ana CSIC ORCID ; Gallego, Isabel CSIC ORCID; Ávila Lucas, Ana Isabel de; Soria, María Eugenia; Gastaminza, Pablo CSIC ORCID; Domingo, Esteban CSIC ORCID; Perales, Celia CSIC ORCID; Mas-Barreiro, Antonio CSICartículo
openAccessGuanosine inhibits_Sabariegos_PV_Art2022.pdf.jpg2022Guanosine inhibits hepatitis C virus replication and increases indel frequencies, associated with altered intracellular nucleotide poolsSabariegos, Rosario; Ortega-Prieto, Ana M. CSIC ORCID; Díaz-Martínez, Luis; Grande-Pérez, Ana CSIC ORCID ; García-Crespo, Carlos; Gallego, Isabel CSIC ORCID; Ávila, Ana Isabel de; Albentosa González, Laura; Soria, María Eugenia; Gastaminza, Pablo CSIC ORCID; Domingo, Esteban CSIC ORCID; Perales, Celia CSIC ORCIDartículo
openAccessHepatitis_C_virus_García_PV_Art2023.pdf.jpg13-mar-2023Hepatitis C virus fitness can influence the extent of infection-mediated epigenetic modifications in the host cellsGarcía-Crespo, Carlos; Francisco-Recuero, Irene CSIC ORCID; Gallego, Isabel CSIC ORCID; Camblor-Murube, Marina; Soria, María Eugenia; López-López, Ana; Ávila, Ana Isabel de; Madejón, Antonio; García-Samaniego, Javier; Domingo, Esteban CSIC ORCID; Sánchez-Pacheco, Aurora CSIC; Perales, Celia CSIC ORCIDartículo
openAccessDomingoE_HepatitisCVirusRNA-DependentRNA.pdf.jpg28-mar-2016Hepatitis C Virus RNA-Dependent RNA Polymerase Interacts with the Akt/PKB Kinase and Induces Its Subcellular RelocalizationValero, María Llanos CSIC; Sabariegos Jareño, Mª del Rosario; Cimas, Francisco J.; Perales, Celia CSIC ORCID; Domingo, Esteban CSIC ORCID; Mas-Barreiro, Antonio CSICartículo
closedAccessaccesoRestringido.pdf.jpg2015Hepatitis C virus-mediated Aurora B kinase inhibition modulates inflammatory pathway and viral infectivityMadejón, Antonio; Sheldon, Julie CSIC ORCID; Francisco-Recuero, Irene CSIC ORCID; Perales, Celia CSIC ORCID; Domínguez-Beato, Mariela; Lasa, Marina CSIC ORCID; Sánchez-Pérez, Isabel CSIC ORCID; Muntané, Jordi CSIC ORCID; Domingo, Esteban CSIC ORCID; García-Samaniego, Javier; Sánchez-Pacheco, Aurora CSICartículo
openAccessHigh SARS-CoV-2.pdf.jpg21-sep-2021High SARS-CoV-2 viral load is associated with a worse clinical outcome of COVID-19 diseaseSoria, María Eugenia; Cortón, Marta; Martínez-González, Brenda; Lobo-Vega, Rebeca; Vázquez-Sirvent, Lucía; López-Rodríguez, Rosario; Almoguera, Berta; Mahillo-Fernández, Ignacio; Mínguez, Pablo; Herrero, Antonio; Taracido, Juan Carlos; Macías-Valcayo, Alicia; Esteban, Jaime; Fernández-Roblas, Ricardo; Gadea, Ignacio; Ruíz-Hornillos, Javier; Ayuso, Carmen; Perales, Celia CSIC ORCIDartículo
openAccessHigh SARSCoV-2 viral load_Soria.pdf.jpg16-nov-2020High SARS-CoV-2 viral load is associated with a worse clinical outcome of COVID-19 diseaseSoria, María Eugenia; Cortón, Marta; Martínez-González, Brenda; Lobo-Vega, Rebeca; Vázquez-Sirvent, Lucía; López-Rodríguez, Rosario; Almoguera, Berta; Mahillo-Fernández, Ignacio; Mínguez, Pablo; Herrero, Antonio; Taracido, Juan Carlos; Macías-Valcayo, Alicia; Esteban, Jaime; Fernández-Roblas, Ricardo; Gadea, Ignacio; Ruíz-Hornillos, Javier; Ayuso, Carmen; Perales, Celia CSIC ORCIDpreprint
openAccessDomingo E High resolution.pdf.jpgene-2015High-resolution hepatitis C virus subtyping using NS5B deep sequencing and phylogeny, an alternative to current methodsQuer, Josep; Domingo, Esteban CSIC ORCID; Saudela, Silvia; Bes, Marta; Perales, Celia CSIC ORCID; Sheldon, Julie CSIC ORCID; Esteban, Juan Ignacioartículo
openAccessPeralesC_HistoricalPerspectiveonthe.pdf.jpg17-nov-2021Historical Perspective on the Discovery of the Quasispecies ConceptDomingo, Esteban CSIC ORCID; García-Crespo, Carlos; Perales, Celia CSIC ORCIDartículo de revisión
openAccessIn vitro Selection_Torres_PV_Art2022.pdf.jpg15-abr-2022In vitro selection of high affinity DNA and RNA aptamers that detect hepatitis C virus core protein of genotypes 1 to 4 and inhibit virus production in cell cultureTorres-Vázquez, Beatriz; Lucas, Ana María de; García-Crespo, Carlos; García-Martín, Juan Antonio; Fragoso, Adrián; Fernández-Algar, María; Perales, Celia CSIC ORCID; Domingo, Esteban CSIC ORCID; Moreno, Miguel; Briones, Carlos CSIC ORCIDartículo
openAccessPeralesC_IncrreasedReplicativeFitness.pdf.jpg14-ago-2014Increased replicative fitness can lead to decreased drug sensitivity of hepatitis C virusSheldon, Julie CSIC ORCID; Beach, Nathan M. CSIC ORCID; Moreno, Elena CSIC; Gallego, Isabel CSIC ORCID; Piñeiro, David; Martínez-Salas, Encarnación CSIC ORCID; Domingo, Esteban CSIC ORCID; Perales, Celia CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpgsep-2014La inhibición de la actividad Aurora quinasa B mediada por VHC regula la respuesta antiinflamatoria en las fases iniciales de la infecciónFrancisco-Recuero, Irene CSIC ORCID; Madejón, Antonio; Sheldon, Julie CSIC ORCID; Perales, Celia CSIC ORCID; Gil, Ana Isabel; Muntané, Jordi CSIC ORCID; Domingo, Esteban CSIC ORCID; García-Samaniego, Javier; Sánchez-Pacheco, Aurora CSICpóster de congreso
openAccessPeralesC-InternalDisequilibria.pdf.jpg8-mar-2017Internal disequilibria and phenotypic diversification during replication of hepatitis C virus in a noncoevolving cellular environmentMoreno, Elena CSIC; Gallego, Isabel CSIC ORCID; Beach, Nathan M. CSIC ORCID; Domingo, Esteban CSIC ORCID; Perales, Celia CSIC ORCIDartículo
openAccessDomingo_ELethalMutagenesisofFootAndMouth.pdf.jpg2011Lethal mutagenesis of foot-and-mouth disease virus involves shifts in sequence spacePerales, Celia CSIC ORCID; Henry, M.; Domingo, Esteban CSIC ORCID; Wain-Hobson, S.; Vartanian, Jean-Pierreartículo