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DerechosPreviewFecha Public.TítuloAutor(es)Tipo
openAccessPNAS_Rai_2021.pdf.jpg16-dic-2021Lattice defects induced by microtubule-stabilizing agents exert a long-range effect on microtubule growth by promoting catastrophesRai, Ankit; Liu, Tianyang; Katrukha, Eugene A.; Estévez-Gallego, Juan CSIC ORCID ; Manka, Szymon W.; Paterson, Ian; Díaz, José Fernando CSIC ORCID ; Kapitein, Lukas C.; Moores, Carolyn A.; Akhmanova, Annaartículo
closedAccessaccesoRestringido.pdf.jpg2005Microtubule interactions with chemically diverse stabilizing agents: Thermodynamics of binding to the paclitaxel site predicts cytotoxicityMartínez Buey, Rubén CSIC ORCID; Barasoain, Isabel CSIC ; Jackson, Evelyn; Meyer, Arndt; Giannakakou, Paraskevi; Paterson, Ian; Mooberry, Susan; Andreu, José Manuel CSIC ORCID ; Díaz, José Fernando CSIC ORCID artículo
closedAccess16-ago-2010Molecular recognition of peloruside A by microtubules. The C24 primary alcohol is essential for biological activity.Pera, Benet CSIC; Razzak, Mina; Trigili, Chiara CSIC; Pineda, Oriol; Canales, Ángeles CSIC ORCID; Martínez Buey, Rubén CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Northcote, Peter; Paterson, Ian; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID artículo
openAccesschembiochem_prota_2017.pdf.jpg16-feb-2017Structural basis of microtubule stabilization by discodermolideProta, Andrea E.; Bargsten, Katja; Redondo-Horcajo, Mariano CSIC ORCID ; Smith III, Amos B.; Yang, Chia-Ping H.; McDaid, Hayley M.; Paterson, Ian; Horwitz, Susan; Díaz, José Fernando CSIC ORCID ; Steinmetz, Michel O.artículo
openAccessacsomega_trigili_2016.pdf.jpg13-dic-2016Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer CellsTrigili, Chiara CSIC; Barasoain, Isabel CSIC ; Sánchez-Murcia, Pedro A. CSIC ORCID; Bargsten, Katja; Redondo-Horcajo, Mariano CSIC ORCID ; Nogales, Aurora CSIC ORCID; Gardner, Nicola M.; Meyer, Arndt; Naylor, Guy J.; Gomez-Rubio, Elena CSIC ORCID; Gago, Federico CSIC ORCID; Steinmetz, Michel O.; Paterson, Ian; Prota, Andrea E.; Díaz, José Fernando CSIC ORCID artículo
closedAccessrestringido.pdf.jpgago-2008The bound conformation of microtubule-stabilizing agents: NMR insights into the bioactive 3D structure of discodermolide and dictyostatinCanales, Ángeles CSIC ORCID; Matesanz, Ruth CSIC ; Gardner, Nicola M.; Andreu, José Manuel CSIC ORCID ; Paterson, Ian; Díaz, José Fernando CSIC ORCID ; Jiménez-Barbero, Jesús CSIC ORCIDartículo
openAccessijms-18-00971-v2.pdf.jpg3-may-2017Zampanolide, a Microtubule-Stabilizing Agent, Is Active in Resistant Cancer Cells and Inhibits Cell MigrationField, Jessica J.; Northcote, Peter; Paterson, Ian; Altmann, Karl-Heinz; Díaz, José Fernando CSIC ORCID ; Miller, John H.artículo