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DerechosPreviewFecha Public.TítuloAutor(es)Tipo
openAccessStructure_Estévez-Gallego_2022.pdf.jpg5-ene-2023Chemical modulation of microtubule structure through the laulimalide/peloruside siteEstévez-Gallego, Juan CSIC ORCID ; Álvarez-Bernad, Beatriz CSIC; Benet, Pera; Wullschleger, Christoph; Raes, Olivier; Menche, Dirk; Martínez, Juan Carlos; Lucena-Agell, Daniel CSIC ORCID ; Prota, Andrea E.; Bonato, Francesca CSIC ORCID; Bargsten, Katja; Cornelus, Jelle; Giménez-Abián, Juan F. CSIC ; Northcote, Peter; Steinmetz, Michel O.; Kamimura, Shinji; Altmann, Karl-Heinz; Paterson, Ian; Gago, Federico CSIC ORCID; Van der Eycken, Johan; Díaz, José Fernando CSIC ORCID ; Oliva, María A. CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2-may-2005Design, synthesis and biological evaluation of novel, simplified analogues of laulimalide: Modification of the side chainPaterson, Ian; Menche, Dirk; Håkansson, Anders E.; Longstaff, Adrian; Wong, David; Barasoain, Isabel CSIC ; Martínez Buey, Rubén CSIC ORCID; Díaz, José Fernando CSIC ORCID artículo
openAccess2011 Canales_et_al.pdf.jpg19-ago-2011Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approachCanales, Ángeles CSIC ORCID; Rodríguez-Salarichs, Javier CSIC; Trigili, Chiara CSIC; Nieto, Lidia CSIC; Coderch, Claire; Andreu, José Manuel CSIC ORCID ; Paterson, Ian; Jiménez-Barbero, Jesús CSIC ORCID; Díaz, José Fernando CSIC ORCID artículo
openAccessPNAS_Rai_2021.pdf.jpg16-dic-2021Lattice defects induced by microtubule-stabilizing agents exert a long-range effect on microtubule growth by promoting catastrophesRai, Ankit; Liu, Tianyang; Katrukha, Eugene A.; Estévez-Gallego, Juan CSIC ORCID ; Manka, Szymon W.; Paterson, Ian; Díaz, José Fernando CSIC ORCID ; Kapitein, Lukas C.; Moores, Carolyn A.; Akhmanova, Annaartículo
closedAccessaccesoRestringido.pdf.jpg2005Microtubule interactions with chemically diverse stabilizing agents: Thermodynamics of binding to the paclitaxel site predicts cytotoxicityMartínez Buey, Rubén CSIC ORCID; Barasoain, Isabel CSIC ; Jackson, Evelyn; Meyer, Arndt; Giannakakou, Paraskevi; Paterson, Ian; Mooberry, Susan; Andreu, José Manuel CSIC ORCID ; Díaz, José Fernando CSIC ORCID artículo
closedAccess16-ago-2010Molecular recognition of peloruside A by microtubules. The C24 primary alcohol is essential for biological activity.Pera, Benet CSIC; Razzak, Mina; Trigili, Chiara CSIC; Pineda, Oriol; Canales, Ángeles CSIC ORCID; Martínez Buey, Rubén CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Northcote, Peter; Paterson, Ian; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID artículo
openAccesschembiochem_prota_2017.pdf.jpg16-feb-2017Structural basis of microtubule stabilization by discodermolideProta, Andrea E.; Bargsten, Katja; Redondo-Horcajo, Mariano CSIC ORCID ; Smith III, Amos B.; Yang, Chia-Ping H.; McDaid, Hayley M.; Paterson, Ian; Horwitz, Susan; Díaz, José Fernando CSIC ORCID ; Steinmetz, Michel O.artículo
openAccessacsomega_trigili_2016.pdf.jpg13-dic-2016Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer CellsTrigili, Chiara CSIC; Barasoain, Isabel CSIC ; Sánchez-Murcia, Pedro A. CSIC ORCID; Bargsten, Katja; Redondo-Horcajo, Mariano CSIC ORCID ; Nogales, Aurora CSIC ORCID; Gardner, Nicola M.; Meyer, Arndt; Naylor, Guy J.; Gomez-Rubio, Elena CSIC ORCID; Gago, Federico CSIC ORCID; Steinmetz, Michel O.; Paterson, Ian; Prota, Andrea E.; Díaz, José Fernando CSIC ORCID artículo
closedAccessrestringido.pdf.jpgago-2008The bound conformation of microtubule-stabilizing agents: NMR insights into the bioactive 3D structure of discodermolide and dictyostatinCanales, Ángeles CSIC ORCID; Matesanz, Ruth CSIC ; Gardner, Nicola M.; Andreu, José Manuel CSIC ORCID ; Paterson, Ian; Díaz, José Fernando CSIC ORCID ; Jiménez-Barbero, Jesús CSIC ORCIDartículo
openAccessijms-18-00971-v2.pdf.jpg3-may-2017Zampanolide, a Microtubule-Stabilizing Agent, Is Active in Resistant Cancer Cells and Inhibits Cell MigrationField, Jessica J.; Northcote, Peter; Paterson, Ian; Altmann, Karl-Heinz; Díaz, José Fernando CSIC ORCID ; Miller, John H.artículo