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Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
openAccess | | 3-jun-2011 | Derivados de bis(aralquil)amino y sistemas (hetero)aromáticos de seis miembros y su uso en el tratamiento de patologías neurodegenerativas, incluida la enfermedad de Alzheimer | García García, Antonio; López Iglesias, Beatriz; García López, Manuela; Conde, Santiago CSIC; Villarroya Sánchez, Mercedes; Pérez, Concepción CSIC ORCID; Rodríguez-Franco, María Isabel CSIC ORCID | solicitud de patente |
openAccess | | 6-jun-2011 | Derivados de bis(aralquil)amino y sistemas [6+5]-heteroaromáticos y su uso en el tratamiento de patologías neurodegenerativas, incluida la enfermedad de Alzheimer | García García, Antonio; López Iglesias, Beatriz; García López, Manuela; Rodríguez-Franco, María Isabel CSIC ORCID ; Conde, Santiago CSIC; Villarroya Sánchez, Mercedes; Pérez, Concepción CSIC ORCID | solicitud de patente |
closedAccess | | 2008 | Design, synthesis, and evaluation of potential inhibitors of nitric oxide synthase | Castaño, Tania; Encinas, Arantxa; Pérez, Concepción CSIC ORCID; Castro, Ana CSIC ORCID; Campillo, Nuria E. CSIC ORCID ; Gil, Carmen CSIC ORCID | artículo |
openAccess | | 15-abr-2021 | Developing novel classes of protein kinase CK1dinhibitors by fusing[1,2,4]triazole with different bicyclic heteroaromatic systems | Grieco, Ilenia; Bissaro, Maicol; Tiz, Davide Benedetto; Pérez, Daniel I. CSIC ORCID; Pérez, Concepción CSIC ORCID; Martínez Gil, Ana CSIC ORCID ; Redenti, Sara; Mariotto, Elena; Bortolozzi, Roberta; Viola, Giampietro; Cozza, Giorgio; Spalluto, Giampiero; Moro, Stefano; Federico, Stephanie | artículo |
closedAccess | | 2014 | Dibenzo[1,4,5]thiadiazepine: A hardly-known heterocyclic system with neuroprotective properties of potential usefulness in the treatment of neurodegenerative diseases | González-Muñoz, Gema C. CSIC; Arce, Mariana P. CSIC; Pérez, Concepción CSIC ORCID; Romero Jódar, Alejandro CSIC ORCID; Villarroya, Mercedes; López, Manuela G.; Conde, Santiago CSIC; Rodríguez-Franco, María Isabel CSIC ORCID | artículo |
closedAccess | | 1989 | Effect of a uridine 5'-diphosphate glucose analogue on herpes simplex keratitis in rabbits and vaginal infection in guinea pigs | Vilas, Pilar; Pérez, Concepción CSIC ORCID; Pérez, Sara; García Villalón, María Dolores; García Gancedo, Angel CSIC; Gil-Fernández, Carmen ; García-López, M. Teresa CSIC ; Heras, F. G. de las | artículo |
openAccess | | 2012 | Effect of phosphodiesterase 7 (PDE7) inhibitors in experimental autoimmune encephalomyelitis mice. Discovery of a new chemically diverse family of compounds | Redondo, Miriam CSIC; Brea, José Manuel; Pérez, Daniel I. CSIC ORCID; Soteras, Ignacio CSIC ORCID; Val, Cristina; Pérez, Concepción CSIC ORCID; Morales-García, José A. CSIC ORCID; Alonso-Gil, Sandra CSIC; Paul-Fernández, Nuria CSIC; Martín-Álvarez, Rocío CSIC; Cadavid, María Isabel; Loza, María Isabel; Pérez Castillo, Ana CSIC ORCID; Mengod Los Arcos, Guadalupe CSIC ORCID; Campillo, Nuria E. CSIC ORCID ; Martínez Gil, Ana CSIC ORCID ; Gil, Carmen CSIC ORCID | artículo |
openAccess | | 2017 | Enzymatic and solid-phase synthesis of new donepezil-based L- and D-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia | Monjas, Leticia CSIC ORCID; Arce, Mariana P. CSIC; León, Rafael CSIC ORCID ; Egea, Javier; Pérez, Concepción CSIC ORCID; Villarroya, Mercedes; López, Manuela G.; Gil, Carmen CSIC ORCID ; Conde, Santiago CSIC; Rodríguez-Franco, María Isabel CSIC ORCID | artículo |
openAccess | | 1994 | Etoposide-induced differentiation of U937 promonocytic cells: AP-1- dependent gene expression and protein kinase C activation | Pérez, Concepción CSIC ORCID; Vilaboa, Nuria E.; Aller, Patricio CSIC | artículo |
closedAccess | | 2011 | Exploring the binding sites of glycogen synthase kinase 3. identification and characterization of allosteric modulation cavities | Palomo, Valle CSIC ORCID ; Soteras, Ignacio CSIC ORCID; Pérez, Daniel I. CSIC ORCID; Pérez, Concepción CSIC ORCID; Gil, Carmen CSIC ORCID ; Campillo, Nuria E. CSIC ORCID ; Martínez Gil, Ana CSIC ORCID | artículo |
openAccess | | 20-oct-2017 | From dual binding site acetylcholinesterase inhibitors to allosteric modulators: A new avenue for disease-modifying drugs in Alzheimer's disease | Chierrito, Talita P. C.; Roca, Carlos CSIC ORCID; Requena-Triguero, Carlos CSIC ORCID; Sebastián-Pérez, Víctor; Pérez, Concepción CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Cañada, F. Javier ; Campillo, Nuria E. CSIC ORCID ; Martínez Gil, Ana CSIC ORCID ; Carvalho, Ivone | artículo |
openAccess | | 24-jun-2021 | From kinase inhibitors to multitarget ligands as powerful drug leads for Alzheimer’s disease using protein-templated synthesis | Martínez Gil, Ana CSIC ORCID ; Nozal, Vanesa CSIC ORCID; García-Rubia, Alfonso CSIC; Cuevas, Eva P. CSIC ORCID ; Pérez, Concepción CSIC ORCID; Palomo, Valle CSIC ORCID ; Tosat-Bitrian, Carlota CSIC ORCID ; Bartolomé Robledo, Fernando CSIC ORCID; Carro, Eva CSIC ORCID; Ramírez, David | artículo |
closedAccess | | 2019 | From simple quinoxalines to potent oxazolo[5,4-: F] quinoxaline inhibitors of glycogen-synthase kinase 3 (GSK3) | Lassagne, F.; Duguépéroux, C.; Roca, Carlos CSIC ORCID; Pérez, Concepción CSIC ORCID; Martínez Gil, Ana CSIC ORCID ; Baratte, B.; Robert, T.; Ruchaud, S.; Bach, S.; Erb, W.; Roisnel, T.; Mongin, F. | artículo |
openAccess | | 16-nov-2000 | Fused 1,2,6- thiadiazine -N,N and N,X- disubstituted dioxide derivatives and corresponding production method. | Martínez Gil, Ana CSIC ORCID ; Gil, Carmen CSIC ORCID ; Castro, Ana CSIC ORCID; Pérez, Concepción CSIC ORCID | patente |
closedAccess | | 2013 | Glycogen synthase kinase-3 inhibitors as potent therapeutic agents for the treatment of Parkinson disease | Morales-García, José A. CSIC ORCID; Susín, Cristina CSIC ORCID; Alonso-Gil, Sandra CSIC; Pérez, Daniel I. CSIC ORCID; Palomo, Valle CSIC ORCID ; Pérez, Concepción CSIC ORCID; Conde, Santiago CSIC; Santos, Ángel; Gil, Carmen CSIC ORCID ; Martínez Gil, Ana CSIC ORCID ; Pérez Castillo, Ana CSIC ORCID | artículo |
openAccess | | 30-ago-2012 | GSK-3 Inhibitors that can be used in neurodegenerative and inflammatory mseases, cancer, diabetes and in regenerative processes | Martínez Gil, Ana CSIC ORCID ; Gil, Carmen CSIC ORCID ; Palomo, Valle CSIC ORCID ; Pérez, Concepción CSIC ORCID; Pérez, Daniel I. CSIC ORCID; Luque Garriga, Francisco Javier | patente |
closedAccess | | 2014 | Guanidinium-based derivatives: Searching for new kinase inhibitors | Diez-Cecilia, Elena; Kelly, Brendan; Pérez, Concepción CSIC ORCID; Zisterer, Daniela M.; Nevin, Daniel K.; Lloyd, David G.; Rozas, Isabel | artículo |
openAccess | | 28-abr-2016 | Heterocyclic GSK-3 allosteric modulators | Martínez Gil, Ana CSIC ORCID ; Gil, Carmen CSIC ORCID ; Palomo, Valle CSIC ORCID ; Pérez, Concepción CSIC ORCID; Pérez, Daniel I. CSIC ORCID; Reyes Rodríguez, Julio Alberto | solicitud de patente |
openAccess | | 13-jul-2017 | Heterocyclic GSK-3 allosteric modulators | Martínez Gil, Ana CSIC ORCID ; Gil, Carmen CSIC ORCID ; Palomo, Valle CSIC ORCID ; Pérez, Concepción CSIC ORCID; Pérez, Daniel I. CSIC ORCID; Reyes Rodríguez, Julio Alberto | solicitud de patente |
openAccess | | 27-ago-2014 | Heterocyclic GSK-3 allosteric modulators | Martínez Gil, Ana CSIC ORCID ; Gil, Carmen CSIC ORCID ; Palomo, Valle CSIC ORCID ; Pérez, Concepción CSIC ORCID; Pérez, Daniel I. CSIC ORCID; Reyes Rodríguez, Julio Alberto | patente |