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openAccessantioxidant_neuroprotective_ligands_calcium.pdf.jpg14-mar-2020Design, synthesis and biological evaluation of new antioxidant and neuroprotective multitarget directed ligands able to block calcium channelsPachòn Angona, Irene; Daniel, Solene; Martin, Hélène; Bonet, Alexandre; Wnorowski, Artur; Maj, Maciej; Jóźwiak, Krzysztof; Silva, Tiago Barros; Refouvelet, Bernard; Borges, Fernanda; Marco-Contelles, José CSIC ORCID; Ismaili, Lhassaneartículo
openAccessJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY.pdf.jpg2019Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer’s disease therapyPachón-Angona, I.; Refouvelet, B.; Andrys, R.; Martin, Hélène; Luzet, V.; Iriepa, Isabel; Moraleda, I.; Diez-Iriepa, Daniel CSIC; Oset-Gasque, María Jesús; Marco-Contelles, José CSIC ORCID; Musilek, K.; Ismaili, L.artículo
openAccessijms-24-09742.pdf.jpg4-jun-2023Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer’s Disease TreatmentDakhlaoui, I.; Bernard, P. J.; Pietrzak, Diana; Simakov, Alexey; Maj, Maciej; Refouvelet, Bernard; Béduneau, Arnaud; Cornu, Raphaël; Józwiak, K.; Chabchoub, Fakher; Iriepa, Isabel; Martin, Hélène; Marco-Contelles, José CSIC ORCID; Ismaili, Lhassaneartículo
openAccessmolecules-21-00400.pdf.jpg24-mar-2016Imidazopyranotacrines as Non-Hepatotoxic, Selective Acetylcholinesterase Inhibitors, and Antioxidant Agents for Alzheimer's Disease TherapyBoulebd, Houssem; Ismaili, L.; Bartolini, Manuela; Bouraiou, Abdelmalek; Andrisano, Vincenza; Martin, Hélène; Bonet, Alexandre; Moraleda, Ignacio; Iriepa, Isabel; Chioua, Mourad CSIC ORCID ; Belfaitah, Ali; Marco-Contelles, José CSIC ORCIDartículo
openAccessMeCP2-E1 isoform.pdf.jpg10-oct-2019MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with diferent protein and DNA interactions compared to MeCP2-E2Martínez de Paz, Alexia; Khajavi, Leila; Martin, Hélène; Claveria-Gimeno, Rafael; Dieck, S. T.; Cheema, Manjinder S.; Sánchez-Mut, José V.; Moksa, Malgorzata M.; Carles, Annaick; Brodie, Nick I.; Sheikh, Taimoor I.; Freenan, Melissa E.; Petrotchenko, Evgeniy V.; Borchers, Christoph H.; Schuman, Erin M.; Zytnicki, Matthias; Velázquez-Campoy, Adrián; Abian, Olga CSIC ORCID; Hirst, Martin; Estelller, Manel; Vincent, John B.; Malnou, Cécile E.; Ausió, Juanartículo
openAccessJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY.pdf.jpg2019Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer’s disease therapyDgachi, Youssef; Martin, Helene; Martin, Hélène; Malek, R; Jun, D.; Janockova, Jana; Sepsova, Vendula; Soukup, Ondrej; Iriepa, Isabel; Moraleda, Ignacio; Maalej, Enma; Carreiras, M. Carmo; Refouvelet, B.; Chabchoub, Fakher; Marco-Contelles, José CSIC ORCID; Ismaili, Lhassaneartículo
closedAccessaccesoRestringido.pdf.jpg2017Synthesis and biological assessment of racemic benzochromenopyrimidinetriones as promising agents for Alzheimer's disease therapyDgachi, Youssef; Martin, Hélène; Bonet, Alexandre; Chioua, Mourad CSIC ORCID ; Iriepa, Isabel; Moraleda, Ignacio; Chabchoub, Fakher; Marco-Contelles, José CSIC ORCID; Ismaili, Lhassaneartículo
openAccessmolecules-21-00634.pdf.jpg14-may-2016Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer’s DiseaseDgachi, Youssef; Bautista-Aguilera, Óscar M. CSIC ORCID; Benchekroun, Mohamed; Martin, Hélène; Bonet, Alexandre; Knez, Damijan; Godyń, Justyna; Malawska, Bárbara; Gobec, Stanislav; Chioua, Mourad CSIC ORCID ; Janockova, Jana; Soukup, O.; Chabchoub, Fakher; Marco-Contelles, José CSIC ORCID; Ismaili, L.artículo
closedAccessaccesoRestringido.pdf.jpg2018Synthesis, Biological Assessment and Molecular Modeling of Racemic QuinoPyranoTacrines for Alzheimer's Disease TherapyChioua, Mourad CSIC ORCID ; Serrano, Estefanía; Dgachi, Youssef; Martin, Hélène; Jun. Daniel Jun; Janockova, Jana; Sepsova, Vendula; Soukup, Ondrej; Moraleda, Ignacio; Chabchoub, Fakher; Ismaili, Lhassan; Iriepa, Isabel; Marco-Contelles, José CSIC ORCIDartículo