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openAccess117538_Chan_Manuscript (2014).pdf.jpg19-nov-2014Functional validation of putative toxin-antitoxin genes from the Gram-positive pathogen Streptococcus pneumoniae: phd-doc is the fourth bona-fide operonChan, Wai Ting CSIC; Yeo, Chew Chieng; Sadowy, Ewa; Espinosa, Manuel CSIC ORCID artículo
closedAccesssep-2011Genetic Regulation of the yefM-yoeB Toxin-Antitoxin Locus of Streptococcus pneumoniaeChan, Wai Ting CSIC; Nieto, Concha ; Harikrishna, J.A.; Khoo, S.K.; Othman, R.Y.; Espinosa, Manuel CSIC ORCID ; Yeo, Chew Chiengartículo
openAccesstoxins-08-00049.pdf.jpg19-feb-2016Heterologous Expression of Toxins from Bacterial Toxin-Antitoxin Systems in Eukaryotic Cells: Strategies and ApplicationsYeo, Chew Chieng; Abu Bakar, Fauziah; Chan, Wai Ting CSIC; Espinosa, Manuel CSIC ORCID ; Harikrishna, Jennifer A.artículo
openAccessmicroorganisms_moreno-córdoba_2021.pdf.jpg15-abr-2021Interactions of the Streptococcus pneumoniae toxin-antitoxin RelBE proteins with their target DNAMoreno-Córdoba, Inmaculada CSIC; Chan, Wai Ting CSIC; Nieto, Concha ; Espinosa, Manuel CSIC ORCID artículo
openAccessKeeping the Wolves at Bay.pdf.jpg22-mar-2016Keeping the Wolves at Bay: Antitoxins of Prokaryotic Type II Toxin-Antitoxin SystemsChan, Wai Ting CSIC; Espinosa, Manuel CSIC ORCID ; Yeo, Chew Chiengartículo
openAccessChan et al, FEMS Microbiol Rev.. 2015.pdf.jpg16-ene-2015One cannot rule them all: Are bacterial toxins antitoxins druggable?Chan, Wai Ting CSIC; Balsa, Dolors; Espinosa, Manuel CSIC ORCID artículo
openAccesspone_Wai Ting Chang_2015.pdf.jpg24-mar-2015Streptococcus pneumoniae induces autophagy through the inhibition of the PI3K-I/Akt/mTOR pathway and ROS hypergeneration in A549 cellsLi, Pu; Shi, Jing; He, Qiao; Hu, Qin; Wang, Yun Ying; Zhang, Li Jun; Chan, Wai Ting CSICartículo
openAccessfmicb-2016.pdf.jpg25-ago-2016The Streptococcus pneumoniae pezAT toxin-antitoxin system reduces β-Lactam resistance and genetic competenceChan, Wai Ting CSIC; Espinosa, Manuel CSIC ORCID artículo
openAccesstoxins-10-00378.pdf.jpg18-sep-2018The streptococcus pneumoniae yefM-yoeB and relBE toxin-antitoxin operons participate in oxidative stress and biofilm formationChan, Wai Ting CSIC; Domenech, Mirian CSIC ORCID; Moreno-Córdoba, Inmaculada CSIC; Navarro-Martínez, Verónica CSIC; Nieto, Concha ; Moscoso, Miriam CSIC ORCID; García, Ernesto CSIC ORCID ; Espinosa, Manuel CSIC ORCID artículo
closedAccessAcceso restringido.pdf.jpgfeb-2007The yefM-yoeB toxin-antitoxin systems of Escherichia coli and Streptococcus pneumoniae: Functional and structural correlationNieto, Concha ; Izhack, Cherny; Kooi Khoo, Seok; García de Lacoba, Mario CSIC ORCID ; Chan, Wai Ting CSIC; Yeo, Chew Chieng; Gazit, Ehud; Espinosa, Manuel CSIC ORCID artículo
openAccessfems microbiology reviews_chan_2023_versión editorial.pdf.jpg15-sep-2023Type II bacterial toxin-antitoxins: hypotheses, facts, and the newfound plethora of the PezAT systemChan, Wai Ting CSIC; Garcillán-Barcia, M. Pilar; Yeo, Chew Chieng; Espinosa, Manuel CSIC ORCID artículo