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DerechosPreviewFecha Public.TítuloAutor(es)Tipo
openAccessValencia_Gregorio_et_al.pdf.jpg2001Les molècules que modulen el dolor. Analgèsia i drogodependència, vint-i-cinc anys després del descobriment de les encefalinesRodríguez, Raquel Emilia; Arsequell, Gemma CSIC ORCID; Espuña, Gemma; Valencia Parera, Gregorio CSICartículo
closedAccess2011Ligand-binding properties of human transthyretinPinto, Marta; Blasi, Daniel; Nieto, Joan; Arsequell, Gemma CSIC ORCID; Valencia Parera, Gregorio CSIC; Planas, Antoni; Quintana, J.; Centeno, Nuria B.artículo
openAccesss13195-022-01016-5.pdf.jpg9-jun-2022Longitudinal evaluation of neuroinflammation and oxidative stress in a mouse model of Alzheimer disease using positron emission tomographyRejc, Luka; Gómez-Vallejo, Vanessa; Joya, Ana; Arsequell, Gemma CSIC ORCID; Egimendia, Ander; Castellnou, Pilar; Ríos-Anglada, Xabier; Cossío, Unai; Baz, Zuriñe; Iglesias, Leyre; Capetillo-Zarate, Estibaliz; Ramos-Cabrer, Pedro; Martín, Abraham; Llop, Jordiartículo
openAccesss13195-021-00883-8.pdf.jpg24-ago-2021Neuroprotection in early stages of Alzheimer’s disease is promoted by transthyretin angiogenic propertiesGião, Tiago; Saavedra, Joana; Vieira, José Ricardo; Teixeira Pinto, Marta; Arsequell, Gemma CSIC ORCID; Cardoso, Isabelartículo
openAccessLEIValidation_20202109_final.pdf.jpg1-dic-2020Optimization of kinetic stabilizers of tetrameric transthyretin: A prospective ligand efficiency-guided approachCotrina, Ellen Y. CSIC ORCID; Balsi, Daniel; Vilà, Marta; Planas, Antoni; Abad-Zapatero, Cele; Centeno, Nuria B.; Quintana, Jordi; Arsequell, Gemma CSIC ORCIDartículo
openAccess2252-10.3233JAD@JAD-200570.pdf.jpg2020Oral Treatment with Iododiflunisal Delays Hippocampal Amyloid-β Formation in a Transgenic Mouse Model of Alzheimer's Disease: A Longitudinal in vivo Molecular Imaging StudyRejc, L.; Gómez-Vallejo, Vanessa; Ríos, X.; Cossío, Unai; Baz, Z.; Mújica, E.; Gião, T.; Cotrina, Ellen Y. CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Quintana, Jordi; Arsequell, Gemma CSIC ORCID; Cardoso, Isabel; Llop, Jordiartículo
closedAccessoct-1999Phosphorylated peptides can be transported by TAP molecules, presented by class I MHC molecules, and recognized by phosphopeptide-specific CTLAndersen, Mads Hald; Bonfil, Jordi Espuny; Neisig, Anne; Arsequell, Gemma CSIC ORCID; Søndergaard, Ib; Neefjes, Jacques; Zeuthen, Jesper; Elliott, Tim; Haurum, John S.artículo
openAccessPreparative_Cotrina_Art2020.pdf.jpg2020Preparative Scale Production of Recombinant Human Transthyretin for Biophysical Studies of Protein-Ligand and Protein-Protein InteractionsCotrina, Ellen Y. CSIC ORCID; Vilà, Marta; Nieto, Joan; Arsequell, Gemma CSIC ORCID; Planas, Antoniartículo
openAccessGales_Luis_et_al.pdf.jpg5-jul-1999Presentation of cytosolic glycosylated peptides by human class I major histocompatibility complex molecules in vivoHaurum, John S.; Høier, Ingelise Bjerring; Arsequell, Gemma CSIC ORCID; Neisig, Anne; Valencia Parera, Gregorio CSIC; Zeuthen, Jesper; Neefjes, Jacques; Elliott, Timartículo
openAccessRadiochemical examination of transthyretin (TTR) brain penetration assisted by iododiflunisal, a TTR tetramer stabilizer and a new candidate drug for AD.pdf.jpg20-sep-2019Radiochemical examination of transthyretin (TTR) brain penetration assisted by iododiflunisal, a TTR tetramer stabilizer and a new candidate drug for ADRíos, Xabier; Gómez-Vallejo, Vanessa; Martín, Abraham; Cossío, Unai; Morcillo, Miguel Ángel; Alemi, Mobina; Cardoso, Isabel Santos; Quintana, Jordi; Jiménez-Bar̀bero, Jesús J.; Cotrina, Ellen Y. CSIC ORCID; Valencia Parera, Gregorio CSIC; Arsequell, Gemma CSIC ORCID; Llop Roig, Jordiartículo
openAccessHaurum_John_et al.pdf.jpg1-ago-1994Recognition of carbohydrate by major histocompatibility complex class I-restricted, glycopeptide-specific cytotoxic T lymphocytesHaurum, Joseph S.; Arsequell, Gemma CSIC ORCID; Lellouch, Annemarie C.; Wong, Simon Y. C.; Dwek, Raymond A.artículo
closedAccess5-ene-2004Regioselective postsynthetic modification of phenylalanine side chains of peptides leading to uncommon ortho-iodinated analoguesEspuña, Gemma; Arsequell, Gemma CSIC ORCID; Valencia Parera, Gregorio CSIC; Barluenga, José CSIC ORCID; Álvarez Gutiérrez, Julia M.; Ballesteros, Alfredo; González, José M.artículo
openAccessijms-21-07166.pdf.jpg28-sep-2020Repurposing Benzbromarone for Familial Amyloid Polyneuropathy: A New Transthyretin Tetramer StabilizerCotrina, Ellen Y. CSIC ORCID; Oliveira, Ângela; Leite, José Pedro; Llop, Jordi; Gales, Luis; Quintana, Jordi; Cardoso, Isabel; Arsequell, Gemma CSIC ORCIDartículo
closedAccess2011Retrospective Mapping of SAR Data for TTR Protein in Chemico-Biological Space Using Ligand Efficiency Indices as a Guide to Drug Discovery StrategiesBlasi, Daniel; Arsequell, Gemma CSIC ORCID; Valencia Parera, Gregorio CSIC; Nieto, Joan; Planas, Antoni; Pinto, Marta; Centeno, Nuria B.; Abad-Zapatero, Cele; Quintana, Jordicomunicación de congreso
closedAccessAlmeida_Maria_et_al.pdf.jpg7-abr-2004Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivativeAlmeida, Maria Rosário; Macedo, Bárbara; Cardoso, Isabel; Alves, Isabel; Valencia Parera, Gregorio CSIC; Arsequell, Gemma CSIC ORCID; Planas, Antoni; Saraiva, Maria Joãoartículo
openAccessd2ce00202g.pdf.jpg1-ene-2022Static discrete disorder in the crystal structure of iododiflunisal: on the importance of hydrogen bond, halogen bond and π-stacking interactionsBarbas, Rafael; Font-Bardía, Mercè; Ballesteros, Alfredo; Arsequell, Gemma CSIC ORCID; Prohens, Rafel; Frontera, Antonioartículo
closedAccessrestringido.pdf.jpg9-feb-2012Structure-activity relationship study of opiorphin, a human dual ectopeptidase inhibitor with antinociceptive propertiesRosa, Mónica CSIC; Arsequell, Gemma CSIC ORCID; Rougeot, Catherine; Calle Jiménez, Luis Pablo CSIC; Marcelo, Filipa CSIC ORCID; Pinto, Marta; Centeno, Nuria B.; Jiménez-Barbero, Jesús CSIC ORCID; Valencia Parera, Gregorio CSICartículo
openAccessmolecules-29-00488-with-cover.pdf.jpg18-ene-2024Synthesis and PET Imaging Biodistribution Studies of Radiolabeled Iododiflunisal, a Transthyretin Tetramer Stabilizer, Candidate Drug for Alzheimer's DiseaseJoshi, Sameer M.; Wilson, Thomas C.; Li, Zibo; Preshlock, Sean; Gómez-Vallejo, Vanessa; Gouverneur, Véronique; Llop, Jordi; Arsequell, Gemma CSIC ORCIDartículo
closedAccess2-jun-2011Synthesis, biological evaluation and structural characterization of novel glycopeptide analogues of nociceptin N/OFQArsequell, Gemma CSIC ORCID; Mayato, Carlos; Rosa, Mónica CSIC; Dorta, Rosa L. CSIC ORCID; Gonzalez-Nuñez, Verónica; Barreto-Valer, Katherine; Marcelo, Filipa CSIC ORCID; Calle Jiménez, Luis Pablo CSIC; Vázquez, Jesús CSIC ORCID CVN; Rodríguez, Raquel E.; Jiménez-Barbero, Jesús CSIC ORCID; Valencia Parera, Gregorio CSICartículo
closedAccessAntinociceptive_Press_release.pdf.jpg7-abr-2009Synthesis, conformation, and biological characterization of a sugar derivative of morphine that is a potent, long-lasting, and nontolerant antinociceptiveArsequell, Gemma CSIC ORCID; Salvatella, Mariona; Valencia Parera, Gregorio CSIC; Fernández-Mayoralas, Alfonso CSIC ORCID ; Fontanella, Marco CSIC; Venturi, Chiara CSIC; Jiménez-Barbero, Jesús CSIC ORCID; Marrón Fernández de Velasco, E.; Rodríguez, Raquel E.artículo