Mostrando resultados 11 a 28 de 28
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Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
openAccess | | 2014 | Phenotypic, genomic and functional characterization reveals no differences between CD138++ and CD138low subpopulations in multiple myeloma cell lines | Paíno, Teresa CSIC ORCID; Sarasquete, María Eugenia; Paiva, Bruno; Krzemiński, Patryk; San-Segundo, Laura CSIC; Corchete, Luis A.; Redondo, Alba; Garayoa, Mercedes CSIC ORCID ; García-Sanz, Ramón; Gutiérrez, Norma Carmen; Ocio, Enrique M. CSIC ORCID ; San Miguel, Jesús F. CSIC ORCID | artículo |
closedAccess | | 2014 | Preclinical activity of the oral proteasome inhibitor mln9708 in myeloma bone disease | García-Gómez, Antonio; Ocio, Enrique M. CSIC ORCID ; Blanco, Juan F.; Hernández-Iglesias, Teresa; Fraile, Susana CSIC; San Miguel, Jesús F. CSIC ORCID; Garayoa, Mercedes CSIC ORCID | artículo |
openAccess | | 2017 | Preclinical anti-myeloma activity of EDO-S101, a new bendamustine-derived molecule with added HDACi activity, through potent DNA damage induction and impairment of DNA repair | López-Iglesias, Ana-Alicia; Herrero, Ana B. CSIC ORCID; Chesi, Marta; San-Segundo, Laura CSIC; González-Méndez, Lorena; Hernández-García, Susana CSIC; Misiewicz-Krzeminska, Irena; Quwaider, Dalia; Martín-Sánchez, Montserrat; Primo, Daniel; Paíno, Teresa CSIC ORCID; Bergsagel, P. Leif; Mehrling, Thomas; González, Marcos CSIC ORCID ; San Miguel, Jesús F. CSIC ORCID; Mateos, Maria Victoria; Gutiérrez, Norma Carmen; Garayoa, Mercedes CSIC ORCID ; Ocio, Enrique M. CSIC ORCID | artículo |
openAccess | | 2020 | Preclinical evaluation of the simultaneous inhibition of MCL-1 and BCL-2 with the combination of S63845 and venetoclax in multiple myeloma | Algarín, Esperanza M.; Díaz-Tejedor, Andrea; Mogollón, Pedro; Hernández-García, Susana CSIC; Corchete, Luis A.; San-Segundo, Laura CSIC; Martín-Sánchez, Montserrat; González-Méndez, Lorena; Schoumacher, Marie; Banquet, Sebastien; Kraus-Berthie, Laurence; Kloos, Ioana; Derreal, Alix; Halilovic, Ensar; Maacke, Heiko; Gutiérrez, Norma Carmen; Mateos, Maria Victoria; Paíno, Teresa CSIC ORCID; Garayoa, Mercedes CSIC ORCID ; Ocio, Enrique M. CSIC ORCID | carta al director |
openAccess | | 24-sep-2020 | Protein Translation Inhibition is Involved in the Activity of the Pan-PIM Kinase Inhibitor PIM447 in Combination with Pomalidomide-Dexamethasone in Multiple Myeloma | Paíno, Teresa CSIC ORCID; González-Méndez, Lorena; San-Segundo, Laura CSIC; Corchete, Luis A.; Hernández-García, Susana CSIC; Díaz-Tejedor, Andrea; Algarín, Esperanza M.; Mogollón, Pedro; Martín-Sánchez, Montserrat; Gutiérrez, Norma Carmen; Mateos, Maria Victoria; Garayoa, Mercedes CSIC ORCID ; Ocio, Enrique M. CSIC ORCID | artículo |
closedAccess | | 2013 | RAF265, a dual BRAF and VEGFR2 inhibitor, prevents osteoclast formation and resorption. Therapeutic implications | García-Gómez, Antonio; Ocio, Enrique M. CSIC ORCID ; Pandiella, Atanasio CSIC ORCID CVN ; San Miguel, Jesús F. CSIC ORCID; Garayoa, Mercedes CSIC ORCID | artículo |
openAccess | | feb-2013 | Sphingosine-1-phosphate activates chemokine-promoted myeloma cell adhesion and migration involving α4β1 integrin function | García-Bernal, David CSIC ORCID; Redondo-Muñoz, Javier CSIC ORCID ; Dios-Esponera, Ana CSIC; Chèvre, Raphael; Bailón, Elvira CSIC ORCID; Garayoa, Mercedes CSIC ORCID ; Arellano-Sánchez, Nohemí CSIC ; Gutiérrez, Norma C.; Hidalgo, Andrés CSIC ORCID; García-Pardo, Angeles CSIC ORCID; Teixidó, Joaquín CSIC ORCID | artículo |
openAccess | | 2021 | Stroma-Mediated Resistance to S63845 and Venetoclax through MCL-1 and BCL-2 Expression Changes Induced by miR-193b-3p and miR-21-5p Dysregulation in Multiple Myeloma | Algarín, Esperanza M.; Quwaider, Dalia; Campos-Laborie, Francisco J.; Díaz-Tejedor, Andrea; Mogollón, Pedro; Vuelta, Elena; Martín-Sánchez, Montserrat; San-Segundo, Laura CSIC; González-Méndez, Lorena; Gutiérrez, Norma Carmen; García-Sanz, Ramón; Paíno, Teresa CSIC ORCID; De Las Rivas, Javier CSIC ORCID CVN ; Ocio, Enrique M. CSIC ORCID ; Garayoa, Mercedes CSIC ORCID | artículo |
openAccess | | 2017 | Synergistic DNA-damaging effect in multiple myeloma with the combination of zalypsis, bor tezomib and dexamethasone | López-Iglesias, Ana-Alicia; González-Méndez, Lorena; San-Segundo, Laura CSIC; Herrero, Ana B. CSIC ORCID; Hernández-García, Susana CSIC; Martín-Sánchez, Montserrat; Gutiérrez, Norma Carmen; Paíno, Teresa CSIC ORCID; Avilés Marín, Pablo; Mateos, Maria Victoria; San Miguel, Jesús F. CSIC ORCID; Garayoa, Mercedes CSIC ORCID ; Ocio, Enrique M. CSIC ORCID | artículo |
openAccess | | 2021 | Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease | García-Gómez, Antonio; Li, Tianlu; Rodríguez-Ubreva, Javier; Ciudad, Laura CSIC ORCID; Català-Moll, Francesc; Godoy-Tena, Gerard; Martín-Sánchez, Montserrat; San-Segundo, Laura CSIC; Muntión, Sandra; Morales, Xabier; Ortiz-de-Solorzano, Carlos; Oyarzabal, Julen; San José-Enériz, Edurne; Esteller, M.; Agirre, Xavier; Prósper, Felipe; Garayoa, Mercedes CSIC ORCID ; Ballestar, Esteban | artículo |
closedAccess | | 11-mar-2021 | Targeting anti-apoptotic proteins in multiple myeloma | Garayoa, Mercedes CSIC ORCID | comunicación de congreso |
openAccess | | 2008 | The effect of the proteasome inhibitor bortezomib on acute myeloid leukemia cells and drug resistance associated with the CD34+ immature phenotype | Colado, Enrique; Álvarez-Fernández, Stela CSIC; Maiso, Patricia; Martín, Jesús; Vidriales, Maria Belén; Garayoa, Mercedes CSIC ORCID ; Ocio, Enrique M. CSIC ORCID ; Montero, Juan Carlos CSIC ORCID; Pandiella, Atanasio CSIC ORCID CVN ; San Miguel, Jesús F. CSIC ORCID | artículo |
openAccess | | 2013 | The epoxyketone-based proteasome inhibitors carfilzomib and orally bioavailable oprozomib have anti-resorptive and bone-anabolic activity in addition to anti-myeloma effects | García-Gómez, Antonio; Ocio, Enrique M. CSIC ORCID ; Blanco, Juan F.; Pandiella, Atanasio CSIC ORCID CVN ; San Miguel, Jesús F. CSIC ORCID; Garayoa, Mercedes CSIC ORCID ; Weilbaecher, K. N. | artículo |
closedAccess | | 2008 | The insulin-like growth factor-I receptor inhibitor NVP-AEW541 provokes cell cycle arrest and apoptosis in multiple myeloma cells | Maiso, Patricia; Ocio, Enrique M. CSIC ORCID ; Garayoa, Mercedes CSIC ORCID ; Montero, Juan Carlos CSIC ORCID; Pandiella, Atanasio CSIC ORCID CVN ; San Miguel, Jesús F. CSIC ORCID | artículo |
openAccess | | 2017 | The novel pan-PIM kinase inhibitor, PIM447, displays dual antimyeloma and bone-protective effects, and potently synergizes with current standards of care | Paíno, Teresa CSIC ORCID; García-Gómez, Antonio; González-Méndez, Lorena; San-Segundo, Laura CSIC; Hernández-García, Susana CSIC; López-Iglesias, Ana-Alicia; Algarín, Esperanza M.; Martín-Sánchez, Montserrat; Corbacho-González, David; Ortiz-de-Solorzano, Carlos; Corchete, Luis A.; Gutiérrez, Norma Carmen; Mateos, Maria Victoria; Garayoa, Mercedes CSIC ORCID ; Ocio, Enrique M. CSIC ORCID | artículo |
closedAccess | | 2009 | The synergy of panobinostat plus doxorubicin in acute myeloid leukemia suggests a role for HDAC inhibitors in the control of DNA repairSynergy of panobinostat and doxorubicin in AML | Maiso, Patricia; Colado, Enrique; Ocio, Enrique M. CSIC ORCID ; Garayoa, Mercedes CSIC ORCID ; Pandiella, Atanasio CSIC ORCID CVN ; San Miguel, Jesús F. CSIC ORCID | artículo |
openAccess | | 2014 | Transcriptomic profile induced in bone marrow mesenchymal stromal cells after interaction with multiple myeloma cells: implications in myeloma progression and myeloma bone disease | García-Gómez, Antonio; De Las Rivas, Javier CSIC ORCID CVN ; Ocio, Enrique M. CSIC ORCID ; Díaz-Rodríguez, Elena CSIC ORCID CVN; Montero, Juan Carlos CSIC ORCID; Martín-Sánchez, Montserrat; Blanco, Juan F.; Sánchez-Guijo, Fermín M. CSIC ORCID; Pandiella, Atanasio CSIC ORCID CVN ; San Miguel, Jesús F. CSIC ORCID; Garayoa, Mercedes CSIC ORCID | artículo |
closedAccess | | 2012 | Transcriptomic rationale for the synergy observed with dasatinib + bortezomib + dexamethasone in multiple myeloma | Queiroz Crusoe, Edvan de; Maiso, Patricia; Fernández-Lázaro, Diego CSIC ORCID; San-Segundo, Laura CSIC; Garayoa, Mercedes CSIC ORCID ; García-Gómez, Antonio; Gutiérrez, Norma Carmen; Delgado, Manuel; Colado, Enrique; Ocio, Enrique M. CSIC ORCID | artículo |