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openAccessG5K_JMB2007.pdf.jpg13-Apr-2007A Novel Two-domain Architecture Within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia coli Glutamate 5-kinaseMarco-Marín, Clara ; Gil-Ortiz, Fernando ; Pérez-Arellano, Isabel ; Cervera, Javier; Fita, Ignacio  ; Rubio, Vicente  artículo
openAccess2016 Brain 139-e3 Author vers.pdf.jpgJan-2016ALDH18A1 gene mutations cause dominant spastic paraplegia SPG9: loss of function effect and plausibility of a dominant negative mechanismPanza, Emanuele; Escamilla-Honrubia, Juan Manuel ; Marco-Marín, Clara ; Gougeard, Nadine ; De Michele, Giuseppe; Brescia Morra, Vincenzo; Liguori, Rocco; Salviati, Leonardo; Donati, Maria Alice; Cusano, Roberto; Pippucci, Tommaso; Ravazzolo, Roberto; Nemeth, Andrea H; Smithson, Sarah; Davies, Sally; Hurst, Jane A; Bordo, Domenico; Rubio, Vicente  ; Seri, Marcoartículo
openAccess2008 Curr Opin Struct Biol 18-673_vers_aut.pdf.jpgDec-2008Arginine and nitrogen storageLlácer, José Luis  ; Fita, Ignacio  ; Rubio, Vicente  artículo
openAccess2013 Mol Genet Metab 110-181 Author vers.pdf.jpgSep-2013Citrin deficiency in a Romanian child living in Spain highlights the worldwide distribution of this defect and illustrates the value of nutritional therapyVitoria, Isidro; Dalmau, Jaime; Ribes, Carmen; Rausell, Dolores; Garcia, Ana Maria; Lopez-Montiel, Javier; Rubio, Vicente  artículo
closedAccessaccesoRestringido.pdf.jpg11-Sep-2014Crystal structures of human carbamoyl phosphate synthetase 1 (CPS1) shed light on domains functions, substrate tunnels and allosteric activation, and allow rationalization of inborn CPS1 deficiencyCima, Sergio de; Polo, Luis Mariano ; Díez-Fernández, Carmen ; Cervera, Javier; Fita, Ignacio  ; Rubio, Vicente  póster de congreso
closedAccessaccesoRestringido.pdf.jpg6-Sep-2016Deciphering carbamoyl phosphate synthetase (CPS1) deficiency and urea cycle regulation by determining the structures of human CPS1 in the absence and in the presence of N-acetyl-L-glutamate.Cima, Sergio de; Polo, Luis Mariano ; Díez-Fernández, Carmen ; Martinez, AI; Cervera, Javier; Fita, Ignacio  ; Rubio, Vicente  póster de congreso
openAccesssebbm2015_Juanma.pdf.jpg7-Sep-2015Deciphering the mechanism by which 1-pyrrolin-5-carboxylate synthetase defects associate with dominant and recessive human pathologiesEscamilla Honrubia, Juan Manuel; Marco-Marín, Clara ; Gougeard, Nadine; Rubio, Vicente  póster de congreso
openAccess2017 Environ Microbiol Rep 9 Vers Autor.pdf.jpg12-Apr-2017Effects of T-loop modification on the PII-signaling protein: Structure of uridylylated Escherichia coli GlnB bound to ATPPalanca, Carles ; Rubio, Vicente  artículo
openAccess2016 Front Micb-07-01677.pdf.jpg28-Oct-2016Expandin Cyanobacterial Nitrogen Regulatory Network: The GntR-Like Regulator PlmA Interacts with the PII-PipX ComplexLabella, Jose I.; Obrebska, Anna; Espinosa, Javier; Salinas, Paloma; Forcada-Nadal, Alicia ; Tremino-Agulló, Lorena ; Rubio, Vicente  ; Contreras, Asunciónartículo
openAccessJ Bacteriol 2012-194-2791 Final Paper.pdf.jpg23-Mar-2012Functional dissection of N-acetylglutamate synthase (ArgA) of Pseudomonas aeruginosa and restoration of its ancestral N-acetylglutamate kinase activitySancho-Vaello, Enea ; Fernández-Murga, María L.; Rubio, Vicente  artículo
openAccess2007 J Bacteriol 189-1254_vers_aut.pdf.jpg6-Oct-2006The Gene Cluster for Agmatine Catabolism of Enterococcus faecalis: Study of Recombinant Putrescine Transcarbamylase and Agmatine Deiminase and a Snapshot of Agmatine Deiminase Catalyzing Its ReactionLlácer, José Luis  ; Polo, Luis Mariano ; Tavárez, Sandra; Alarcón, Benito; Hilario, Rebeca; Rubio, Vicente  artículo
openAccessRubio_IBV.pdf.jpgMar-2004Happy microbes in hostile niches. A symposium on extremophilesRubio, Vicente  artículo
closedAccessaccesoRestringido.pdf.jpg19-Jul-2014Human carbamoyl phosphate synthetase: structure, function and pathologyRubio, Vicente  ; Cima, Sergio de; Polo, Luis Mariano ; Díez-Fernández, Carmen ; Cervera, Javier; Fita, Ignacio  comunicación de congreso
openAccess2018 Hum Mutat 39-1002 Author vers.pdf.jpgJul-2018Insight into vitamin B6 -dependent epilepsy due to PLPBP (previously PROSC) missense mutationsTremino-Agulló, Lorena ; Forcada-Nadal, Alicia ; Rubio, Vicente  artículo
openAccessInsight.pdf.jpg18-Apr-2012Insight on an arginine synthesis metabolon from the tetrameric structure of yeast acetylglutamate kinaseCima, Sergio de; Gil-Ortiz, Fernando ; Crabeel, Marjolaine; Fita, Ignacio  ; Rubio, Vicente  artículo
openAccess2015 FEBS Open Bio 5-76.pdf.jpg28-Jan-2015Ligand binding specificity of RutR, a member of the TetR family of transcription regulators in Escherichia coliNguyen Le Minh, Phu; de Cima, Sergio; Bervoets, Indra; Maes, Dominique; Rubio, Vicente  ; Charlier, Danielartículo
closedAccessaccesoRestringido.pdf.jpg27-Aug-2014Looking at Metabolic Regulation and Inborn Errors from a Structural Viewpoint: a Urea Cycle ExampleCima, Sergio de; Polo, Luis Mariano ; Díez-Fernández, Carmen ; Cervera, Javier; Fita, Ignacio  ; Rubio, Vicente  comunicación de congreso
openAccessGil-Acta-D-1999-v55-n7-p1350.pdf.jpg1999N-acetyi-L-glutamate kinase from Escherichia coli: Cloning of the gene, purification and crystallization of the recombinant enzyme and preliminary X-ray analysis of the free and ligand-bound formsGil-Ortiz, Fernando ; Ramón-Maiques, Santiago ; Marina, Alberto  ; Fita, Ignacio  ; Rubio, Vicente  artículo
openAccessPLoS ONE 2012-7- e31528.pdf.jpg20-Feb-2012New Insight into the Transcarbamylase Family: The Structure of Putrescine Transcarbamylase, a Key Catalyst for Fermentative Utilization of AgmatinePolo, Luis Mariano ; Gil-Ortiz, Fernando ; Cantín, Angel; Rubio, Vicente  artículo
openAccess2017 Front Microbiol 08-01244.pdf.jpg11-Jul-2017PipY, a Member of the Conserved COG0325 Family of PLP-Binding Proteins, Expands the Cyanobacterial Nitrogen Regulatory Network.Labella, José I.; Cantos, Raquel; Espinosa, Javier; Forcada-Nadal, Alicia ; Rubio, Vicente  ; Contreras, Asunciónartículo